AU2015292889C1 - Molecules that selectively activate regulatory T cells for the treatment of autoimmune diseases - Google Patents

Molecules that selectively activate regulatory T cells for the treatment of autoimmune diseases Download PDF

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Publication number
AU2015292889C1
AU2015292889C1 AU2015292889A AU2015292889A AU2015292889C1 AU 2015292889 C1 AU2015292889 C1 AU 2015292889C1 AU 2015292889 A AU2015292889 A AU 2015292889A AU 2015292889 A AU2015292889 A AU 2015292889A AU 2015292889 C1 AU2015292889 C1 AU 2015292889C1
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protein
fusion protein
cells
seq
amino acid
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AU2015292889B2 (en
AU2015292889A1 (en
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Jeffrey Greve
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Delinia Inc
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Delinia Inc
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Priority to AU2020203480A priority Critical patent/AU2020203480A1/en
Priority to AU2022204946A priority patent/AU2022204946A1/en
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/55IL-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/2013IL-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2015292889A 2014-07-21 2015-07-20 Molecules that selectively activate regulatory T cells for the treatment of autoimmune diseases Withdrawn - After Issue AU2015292889C1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2020203480A AU2020203480A1 (en) 2014-07-21 2020-05-27 Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases
AU2022204946A AU2022204946A1 (en) 2014-07-21 2022-07-11 Molecules that selectively activate regulatory t cells for the treatment of autoimmune disease

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461999241P 2014-07-21 2014-07-21
US61/999,241 2014-07-21
PCT/US2015/041177 WO2016014428A2 (en) 2014-07-21 2015-07-20 Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases

Related Child Applications (1)

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AU2020203480A Division AU2020203480A1 (en) 2014-07-21 2020-05-27 Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases

Publications (3)

Publication Number Publication Date
AU2015292889A1 AU2015292889A1 (en) 2016-01-28
AU2015292889B2 AU2015292889B2 (en) 2020-02-27
AU2015292889C1 true AU2015292889C1 (en) 2023-01-19

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AU2015292889A Withdrawn - After Issue AU2015292889C1 (en) 2014-07-21 2015-07-20 Molecules that selectively activate regulatory T cells for the treatment of autoimmune diseases
AU2020203480A Abandoned AU2020203480A1 (en) 2014-07-21 2020-05-27 Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases
AU2022204946A Withdrawn AU2022204946A1 (en) 2014-07-21 2022-07-11 Molecules that selectively activate regulatory t cells for the treatment of autoimmune disease

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AU2020203480A Abandoned AU2020203480A1 (en) 2014-07-21 2020-05-27 Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases
AU2022204946A Withdrawn AU2022204946A1 (en) 2014-07-21 2022-07-11 Molecules that selectively activate regulatory t cells for the treatment of autoimmune disease

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US (6) US20170051029A1 (enExample)
EP (2) EP3172227B9 (enExample)
JP (2) JP6768633B2 (enExample)
KR (1) KR102493543B1 (enExample)
CN (2) CN114133456A (enExample)
AU (3) AU2015292889C1 (enExample)
CA (1) CA2954847A1 (enExample)
DK (1) DK3172227T3 (enExample)
EA (2) EA038361B1 (enExample)
ES (1) ES2763198T3 (enExample)
GB (1) GB2538666A (enExample)
HU (1) HUE046065T2 (enExample)
IL (3) IL289475B2 (enExample)
LT (1) LT3172227T (enExample)
MX (2) MX378790B (enExample)
PL (1) PL3172227T3 (enExample)
PT (1) PT3172227T (enExample)
RS (1) RS59789B1 (enExample)
SG (2) SG11201700514SA (enExample)
SI (1) SI3172227T1 (enExample)
WO (1) WO2016014428A2 (enExample)
ZA (1) ZA201700344B (enExample)

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