AU2015259294A1 - Quantitation of tamoxifen and metabolites thereof by mass spectrometry - Google Patents
Quantitation of tamoxifen and metabolites thereof by mass spectrometry Download PDFInfo
- Publication number
- AU2015259294A1 AU2015259294A1 AU2015259294A AU2015259294A AU2015259294A1 AU 2015259294 A1 AU2015259294 A1 AU 2015259294A1 AU 2015259294 A AU2015259294 A AU 2015259294A AU 2015259294 A AU2015259294 A AU 2015259294A AU 2015259294 A1 AU2015259294 A1 AU 2015259294A1
- Authority
- AU
- Australia
- Prior art keywords
- tamoxifen
- limit
- quantitation
- equal
- detection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/72—Mass spectrometers
- G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0027—Methods for using particle spectrometers
- H01J49/0031—Step by step routines describing the use of the apparatus
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
- H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/10—Ion sources; Ion guns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/17—Nitrogen containing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ecology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2018275011A AU2018275011A1 (en) | 2014-05-12 | 2018-12-07 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
| AU2020239700A AU2020239700B2 (en) | 2014-05-12 | 2020-09-23 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
| AU2022202628A AU2022202628B2 (en) | 2014-05-12 | 2022-04-20 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
| AU2023204389A AU2023204389B2 (en) | 2014-05-12 | 2023-07-07 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
| AU2024227191A AU2024227191B2 (en) | 2014-05-12 | 2024-10-09 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461992214P | 2014-05-12 | 2014-05-12 | |
| US61/992,214 | 2014-05-12 | ||
| PCT/US2015/030419 WO2015175561A1 (en) | 2014-05-12 | 2015-05-12 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2018275011A Division AU2018275011A1 (en) | 2014-05-12 | 2018-12-07 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2015259294A1 true AU2015259294A1 (en) | 2016-12-01 |
Family
ID=54367635
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2015259294A Abandoned AU2015259294A1 (en) | 2014-05-12 | 2015-05-12 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
| AU2018275011A Abandoned AU2018275011A1 (en) | 2014-05-12 | 2018-12-07 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
| AU2020239700A Active AU2020239700B2 (en) | 2014-05-12 | 2020-09-23 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
| AU2022202628A Active AU2022202628B2 (en) | 2014-05-12 | 2022-04-20 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
| AU2023204389A Active AU2023204389B2 (en) | 2014-05-12 | 2023-07-07 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
| AU2024227191A Active AU2024227191B2 (en) | 2014-05-12 | 2024-10-09 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2018275011A Abandoned AU2018275011A1 (en) | 2014-05-12 | 2018-12-07 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
| AU2020239700A Active AU2020239700B2 (en) | 2014-05-12 | 2020-09-23 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
| AU2022202628A Active AU2022202628B2 (en) | 2014-05-12 | 2022-04-20 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
| AU2023204389A Active AU2023204389B2 (en) | 2014-05-12 | 2023-07-07 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
| AU2024227191A Active AU2024227191B2 (en) | 2014-05-12 | 2024-10-09 | Quantitation of tamoxifen and metabolites thereof by mass spectrometry |
Country Status (9)
| Country | Link |
|---|---|
| US (7) | US9459267B2 (cg-RX-API-DMAC10.html) |
| EP (2) | EP3143392B1 (cg-RX-API-DMAC10.html) |
| JP (5) | JP6279104B2 (cg-RX-API-DMAC10.html) |
| CN (2) | CN110044998B (cg-RX-API-DMAC10.html) |
| AU (6) | AU2015259294A1 (cg-RX-API-DMAC10.html) |
| BR (1) | BR112016026459B1 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2948823C (cg-RX-API-DMAC10.html) |
| SA (1) | SA516380291B1 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2015175561A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4718073A3 (en) * | 2008-12-24 | 2026-07-29 | Quest Diagnostics Investments LLC | Mass spectrometry assay for congenital adrenal hyperplasia |
| CN110044998B (zh) * | 2014-05-12 | 2021-12-14 | 奎斯特诊断投资公司 | 通过质谱法定量他莫昔芬及其代谢物 |
| CN105159539B (zh) * | 2015-09-10 | 2018-06-01 | 京东方科技集团股份有限公司 | 可穿戴设备的触控响应方法、装置及可穿戴设备 |
| CA3153535A1 (en) | 2019-10-10 | 2021-04-15 | Rachel MULLEN | Liquid chromatography-mass spectrometry (lc-ms) methods for analyzing ampholyte lot variation |
| EP4097256A1 (en) | 2020-01-31 | 2022-12-07 | Regeneron Pharmaceuticals, Inc. | Use of liquid chromatography and mass spectrometry to characterize oligonucleotides |
| US12105102B2 (en) | 2022-03-30 | 2024-10-01 | University Of Utah Research Foundation | Methods for quantifying insulin-like growth factor-1 and insulin-like growth factor-2 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5119827A (en) * | 1990-09-05 | 1992-06-09 | Board Of Regents, The University Of Texas System | Mechanisms of antiestrogen resistance in breast cancer |
| US5605798A (en) | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
| PT700521E (pt) | 1993-05-28 | 2003-10-31 | Baylor College Medicine | Metodo e espectrometro de massa para dessorcao e ionizacao de analitos |
| IES950928A2 (en) * | 1995-12-08 | 1996-02-21 | Bunskellig Limited | "A process for analysing a fluid" |
| GB9717926D0 (en) | 1997-08-22 | 1997-10-29 | Micromass Ltd | Methods and apparatus for tandem mass spectrometry |
| JP2002502086A (ja) | 1998-01-23 | 2002-01-22 | アナリティカ オブ ブランフォード インコーポレーテッド | 表面からの質量分光測定 |
| CN1871517A (zh) * | 2002-02-19 | 2006-11-29 | 免疫公司 | 快速有效分离循环癌细胞的方法和试剂 |
| EP2050443B1 (en) * | 2002-12-18 | 2017-05-24 | Besins Healthcare Luxembourg SARL | Reduction of breast density with 4-hydroxy tamoxifen |
| CA2519980C (en) | 2003-04-01 | 2012-04-10 | Laboratoires Besins International | Prevention and treatment of breast cancer with 4-hydroxy tamoxifen |
| WO2005064344A1 (ja) * | 2003-12-26 | 2005-07-14 | Takeda Pharmaceutical Company Limited | 脂質代謝異常症の予測方法 |
| MY145634A (en) * | 2003-12-29 | 2012-03-15 | Bristol Myers Squibb Co | Pyrrolotriazine compounds as kinase inhibitors |
| US20060105045A1 (en) * | 2004-11-08 | 2006-05-18 | Buchanan Charles M | Cyclodextrin solubilizers for liquid and semi-solid formulations |
| US20090291134A1 (en) * | 2006-11-21 | 2009-11-26 | Jina Pharmaceuticals, Inc. | Endoxifen methods and compositions in the treatment of psychiatric and neurodegenerative diseases |
| US8017403B2 (en) * | 2007-06-14 | 2011-09-13 | Quest Diagnostics Investments Incorporated | Mass spectrometry method for measuring vitamin B6 in body fluid |
| US20090134325A1 (en) * | 2007-11-27 | 2009-05-28 | Goldman Mildred M | Methods for detecting estradiol by mass spectrometry |
| US8916385B2 (en) * | 2007-12-13 | 2014-12-23 | Quest Diagnostics Investments, Inc. | Methods for detecting estrone by mass spectrometry |
| US7834313B2 (en) | 2008-08-08 | 2010-11-16 | Quest Diagnostics Investments Incorporated | Mass spectrometry assay for plasma-renin |
| IL313131A (en) * | 2009-02-11 | 2024-07-01 | Caris Mpi Inc | Molecular characterization of tumors |
| US20110081675A1 (en) * | 2009-10-06 | 2011-04-07 | Wisconsin Alumni Research Foundation | Metabolic Biomarkers Of Drug-Induced Cardiotoxicity |
| WO2012119010A2 (en) * | 2011-03-01 | 2012-09-07 | Indiana University Research And Technology Corporation | Materials for inhibiting aromatase and method of using the same to diagnose, treat and monitor breast cancer |
| WO2012167126A1 (en) | 2011-06-03 | 2012-12-06 | Purdue Research Foundation | Ion generation using modified wetted porous materials |
| WO2013134230A1 (en) * | 2012-03-05 | 2013-09-12 | Xavier University | Boron-based 4-hydroxytamoxifen and endoxifen prodrugs as treatment for breast cancer |
| JP6216786B2 (ja) * | 2012-07-17 | 2017-10-18 | ソウル大学校産学協力団Ｓｎｕ Ｒ＆Ｄｂ Ｆｏｕｎｄａｔｉｏｎ | 質量スペクトルの再現性向上方法およびこれを用いた定量分析方法 |
| CN103494787B (zh) * | 2013-07-22 | 2014-10-29 | 南通广泰生化制品有限公司 | 枸橼酸他莫昔芬滴丸 |
| CN110044998B (zh) * | 2014-05-12 | 2021-12-14 | 奎斯特诊断投资公司 | 通过质谱法定量他莫昔芬及其代谢物 |
-
2015
- 2015-05-12 CN CN201910220665.6A patent/CN110044998B/zh active Active
- 2015-05-12 EP EP15793289.8A patent/EP3143392B1/en active Active
- 2015-05-12 EP EP23157017.7A patent/EP4220178A3/en active Pending
- 2015-05-12 AU AU2015259294A patent/AU2015259294A1/en not_active Abandoned
- 2015-05-12 US US14/710,311 patent/US9459267B2/en active Active
- 2015-05-12 CA CA2948823A patent/CA2948823C/en active Active
- 2015-05-12 WO PCT/US2015/030419 patent/WO2015175561A1/en not_active Ceased
- 2015-05-12 BR BR112016026459-2A patent/BR112016026459B1/pt active IP Right Grant
- 2015-05-12 CN CN201580037630.9A patent/CN106537139B/zh active Active
- 2015-05-12 JP JP2016567654A patent/JP6279104B2/ja active Active
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2016
- 2016-10-03 US US15/284,248 patent/US9835606B2/en active Active
- 2016-11-13 SA SA516380291A patent/SA516380291B1/ar unknown
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2017
- 2017-12-04 US US15/830,812 patent/US10830746B2/en active Active
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2018
- 2018-01-16 JP JP2018004851A patent/JP6821610B2/ja active Active
- 2018-12-07 AU AU2018275011A patent/AU2018275011A1/en not_active Abandoned
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2020
- 2020-09-23 AU AU2020239700A patent/AU2020239700B2/en active Active
- 2020-11-09 US US17/093,472 patent/US11428682B2/en active Active
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2021
- 2021-01-06 JP JP2021000689A patent/JP2021073450A/ja active Pending
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2022
- 2022-04-20 AU AU2022202628A patent/AU2022202628B2/en active Active
- 2022-08-23 US US17/893,950 patent/US11835505B2/en active Active
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2023
- 2023-05-16 JP JP2023080724A patent/JP2023109874A/ja active Pending
- 2023-07-07 AU AU2023204389A patent/AU2023204389B2/en active Active
- 2023-10-25 US US18/494,030 patent/US12270803B2/en active Active
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2024
- 2024-10-09 AU AU2024227191A patent/AU2024227191B2/en active Active
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2025
- 2025-02-07 JP JP2025018885A patent/JP7884626B2/ja active Active
- 2025-03-07 US US19/074,121 patent/US20260118337A1/en active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HB | Alteration of name in register |
Owner name: QUEST DIAGNOSTICS INVESTMENTS LLC Free format text: FORMER NAME(S): QUEST DIAGNOSTICS INVESTMENTS INCORPORATED |
|
| MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |