AU2015242495B2 - A therapeutic agent for use in the treatment of infections - Google Patents

A therapeutic agent for use in the treatment of infections Download PDF

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Publication number
AU2015242495B2
AU2015242495B2 AU2015242495A AU2015242495A AU2015242495B2 AU 2015242495 B2 AU2015242495 B2 AU 2015242495B2 AU 2015242495 A AU2015242495 A AU 2015242495A AU 2015242495 A AU2015242495 A AU 2015242495A AU 2015242495 B2 AU2015242495 B2 AU 2015242495B2
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AU
Australia
Prior art keywords
therapeutic agent
acetyl
nano
micro
donor
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AU2015242495A
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AU2015242495A1 (en
Inventor
Adrian Neville Fellows
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aga Nanotech Ltd
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Aga Nanotech Ltd
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Publication of AU2015242495A1 publication Critical patent/AU2015242495A1/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/132Amines having two or more amino groups, e.g. spermidine, putrescine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/327Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/40Peroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
AU2015242495A 2014-04-01 2015-03-24 A therapeutic agent for use in the treatment of infections Active AU2015242495B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1405874.7 2014-04-01
GBGB1405874.7A GB201405874D0 (en) 2014-04-01 2014-04-01 A therapeutic agent for use in the treatment of infections
GBGB1415063.5A GB201415063D0 (en) 2014-04-01 2014-08-26 A therapeutic agent for use in the treatment of infections
GB1415063.5 2014-08-26
PCT/GB2015/000100 WO2015150722A1 (en) 2014-04-01 2015-03-24 A therapeutic agent for use in the treatment of infections

Publications (2)

Publication Number Publication Date
AU2015242495A1 AU2015242495A1 (en) 2016-10-06
AU2015242495B2 true AU2015242495B2 (en) 2020-04-30

Family

ID=50737835

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2015242495A Active AU2015242495B2 (en) 2014-04-01 2015-03-24 A therapeutic agent for use in the treatment of infections

Country Status (16)

Country Link
US (2) US9913805B2 (enExample)
EP (2) EP3125874B1 (enExample)
JP (1) JP6573286B2 (enExample)
KR (2) KR102359855B1 (enExample)
CN (1) CN106456557B (enExample)
AU (1) AU2015242495B2 (enExample)
CA (1) CA2943431C (enExample)
DK (1) DK3125874T3 (enExample)
ES (2) ES2953755T3 (enExample)
GB (3) GB201405874D0 (enExample)
IL (1) IL247969B (enExample)
MX (1) MX2016012757A (enExample)
NZ (1) NZ724298A (enExample)
SG (2) SG11201608093WA (enExample)
WO (1) WO2015150722A1 (enExample)
ZA (1) ZA201606387B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201405874D0 (en) * 2014-04-01 2014-05-14 Aga Nanotech Ltd A therapeutic agent for use in the treatment of infections
CN107281220B (zh) * 2016-03-31 2020-02-14 中国科学院上海硅酸盐研究所 一种介孔氧化硅基活性氧(ros)放疗增敏剂及其制备方法
CN106860032B (zh) * 2016-10-25 2021-04-09 咏达生医材料股份有限公司 一种气态皮肤供氧美白产品及其应用
JP2019194162A (ja) * 2018-05-01 2019-11-07 ツァ ギャリー 肌の酸素供給による美白及び加熱機能を備えた通気性材料
JP7372706B2 (ja) 2019-10-10 2023-11-01 アルファ タウ メディカル リミテッド 放射線治療源の湿式調製
GB2592911B (en) * 2020-02-28 2023-06-28 Aga Nanotech Ltd A plasma-activatable wound dressing for treatment of infections
GB202005556D0 (en) 2020-04-16 2020-06-03 Aga Nanotech Ltd Covid face mask

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060088498A1 (en) * 2004-10-27 2006-04-27 Truox, Inc. Anti-microbial composition using in-situ generation of an oxidizing agent

Family Cites Families (18)

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Publication number Priority date Publication date Assignee Title
WO1997007777A1 (en) * 1995-08-15 1997-03-06 Robert Eric Montgomery Peroxidase-activating oral compositions
DE59912558D1 (de) * 1999-07-02 2005-10-20 Cognis Ip Man Gmbh Mikrokapseln - IV
AU4477001A (en) * 2000-04-18 2001-10-30 Peptron Inc. Injectable sustained release pharmaceutical composition and processes for preparing the same
KR100342746B1 (ko) * 2000-06-27 2002-07-03 김찬화 인슐린의 방출제어제제 및 그 방법
GB0411304D0 (en) * 2004-05-21 2004-06-23 Fellows Adrian N An antimicrobial composition
EP1919507A2 (en) * 2005-08-04 2008-05-14 Thomas William Rademacher Nanoparticles comprising antibacterial ligands
KR20070071225A (ko) * 2005-12-29 2007-07-04 애경산업(주) 치아 미백용 조성물
GB0711952D0 (en) 2007-06-20 2007-08-01 King S College London Microspheres
WO2009108407A1 (en) * 2008-02-25 2009-09-03 The University Of North Carolina At Charlotte Office Of Technology Transfer Biodegradable therapeutic nanoparticles containing an antimicrobial agent
CA2730995C (en) * 2008-07-17 2016-11-22 Micell Technologies, Inc. Drug delivery medical device
US8969282B2 (en) * 2009-02-05 2015-03-03 American Sterilizer Company Low odor, hard surface sporicide
KR101136028B1 (ko) * 2009-04-27 2012-04-18 한양대학교 산학협력단 다공성 마이크로스피어의 제조방법
US8889161B2 (en) * 2009-04-27 2014-11-18 Premier Dental Products Company Microencapsulated compositions and methods for tissue mineralization
NZ600269A (en) * 2009-05-20 2014-02-28 Dec Int Nz Ltd Delivery device for treatment of mastitis
US9187594B2 (en) * 2010-02-09 2015-11-17 The Regents Of The University Of Michigan Nano-fibrous microspheres and methods for making the same
HUE033386T2 (en) * 2010-07-09 2017-11-28 Innocore Tech B V Release of Biodegradable Phase Separated Segmented Multiblock Copolymers and Biologically Active Polypeptides
EP2611466B1 (en) * 2010-08-30 2019-06-12 President and Fellows of Harvard College Shear controlled release of thrombolytic therapies for stenotic lesions
GB201405874D0 (en) * 2014-04-01 2014-05-14 Aga Nanotech Ltd A therapeutic agent for use in the treatment of infections

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060088498A1 (en) * 2004-10-27 2006-04-27 Truox, Inc. Anti-microbial composition using in-situ generation of an oxidizing agent

Also Published As

Publication number Publication date
CN106456557B (zh) 2021-02-05
EP3848022B1 (en) 2023-06-07
EP3848022A1 (en) 2021-07-14
EP3848022C0 (en) 2023-06-07
EP3125874A1 (en) 2017-02-08
GB201617053D0 (en) 2016-11-23
CA2943431C (en) 2022-08-23
NZ724298A (en) 2022-07-01
KR102482597B1 (ko) 2022-12-29
SG11201608093WA (en) 2016-10-28
US20170079930A1 (en) 2017-03-23
GB201405874D0 (en) 2014-05-14
KR102359855B1 (ko) 2022-02-08
US20180207105A1 (en) 2018-07-26
CN106456557A (zh) 2017-02-22
US10933026B2 (en) 2021-03-02
GB2538923A (en) 2016-11-30
SG10201801524PA (en) 2018-04-27
WO2015150722A1 (en) 2015-10-08
GB2538923B (en) 2020-03-25
DK3125874T3 (da) 2021-03-22
ZA201606387B (en) 2017-11-29
AU2015242495A1 (en) 2016-10-06
ES2855985T3 (es) 2021-09-27
EP3125874B1 (en) 2020-12-30
KR20160144408A (ko) 2016-12-16
JP2017510648A (ja) 2017-04-13
US9913805B2 (en) 2018-03-13
JP6573286B2 (ja) 2019-09-11
GB201415063D0 (en) 2014-10-08
MX2016012757A (es) 2017-04-27
IL247969B (en) 2018-12-31
CA2943431A1 (en) 2015-10-08
KR20220021029A (ko) 2022-02-21
ES2953755T3 (es) 2023-11-15

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