AU2015242374B2 - New use of N,N-bis-2-mercaptoethyl isophthalamide - Google Patents

New use of N,N-bis-2-mercaptoethyl isophthalamide Download PDF

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Publication number
AU2015242374B2
AU2015242374B2 AU2015242374A AU2015242374A AU2015242374B2 AU 2015242374 B2 AU2015242374 B2 AU 2015242374B2 AU 2015242374 A AU2015242374 A AU 2015242374A AU 2015242374 A AU2015242374 A AU 2015242374A AU 2015242374 B2 AU2015242374 B2 AU 2015242374B2
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AU
Australia
Prior art keywords
nbmi
patient
treatment
symptom
ascorbate
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AU2015242374A
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AU2015242374A1 (en
Inventor
Boyd Eugene HALEY
Ragnar Axel Theodor KLINGBERG
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EmeraMed Ltd
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EmeraMed Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/10Expectorants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AU2015242374A 2014-04-04 2015-03-31 New use of N,N-bis-2-mercaptoethyl isophthalamide Active AU2015242374B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1406115.4A GB2524831A (en) 2014-04-04 2014-04-04 New pharmaceutical use
GB1406115.4 2014-04-04
PCT/GB2015/050999 WO2015150793A1 (en) 2014-04-04 2015-03-31 New use of n,n-bis-2-mercaptoethyl isophthalamide

Publications (2)

Publication Number Publication Date
AU2015242374A1 AU2015242374A1 (en) 2016-10-13
AU2015242374B2 true AU2015242374B2 (en) 2019-10-10

Family

ID=50776843

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2015242374A Active AU2015242374B2 (en) 2014-04-04 2015-03-31 New use of N,N-bis-2-mercaptoethyl isophthalamide

Country Status (36)

Country Link
US (1) US9782368B2 (enExample)
EP (1) EP3125876B8 (enExample)
JP (1) JP6474423B2 (enExample)
KR (1) KR102482699B1 (enExample)
CN (1) CN106132405B (enExample)
AU (1) AU2015242374B2 (enExample)
BR (1) BR112016022880B1 (enExample)
CA (1) CA2944113C (enExample)
CL (1) CL2016002499A1 (enExample)
CY (1) CY1121235T1 (enExample)
DK (1) DK3125876T3 (enExample)
EA (1) EA032116B1 (enExample)
EC (1) ECSP16078100A (enExample)
ES (1) ES2659174T3 (enExample)
GB (1) GB2524831A (enExample)
HR (1) HRP20180325T1 (enExample)
HU (1) HUE036206T2 (enExample)
IL (1) IL248027B (enExample)
LT (1) LT3125876T (enExample)
MA (1) MA39833B1 (enExample)
ME (1) ME03012B (enExample)
MX (1) MX2016012591A (enExample)
NO (1) NO3125876T3 (enExample)
NZ (1) NZ724678A (enExample)
PE (1) PE20170586A1 (enExample)
PH (1) PH12016501975A1 (enExample)
PL (1) PL3125876T3 (enExample)
PT (1) PT3125876T (enExample)
RS (1) RS56905B1 (enExample)
SA (1) SA516371966B1 (enExample)
SG (1) SG11201607478RA (enExample)
SI (1) SI3125876T1 (enExample)
SM (1) SMT201800116T1 (enExample)
UA (1) UA119558C2 (enExample)
WO (1) WO2015150793A1 (enExample)
ZA (1) ZA201606406B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202005057D0 (en) 2020-04-06 2020-05-20 Emeramed Ltd New Use
CN114778234B (zh) * 2022-03-18 2025-08-15 武汉新烽光电股份有限公司 一种用于微流控总磷测试的抗坏血酸溶液的保存方法及保存结构
WO2026037909A1 (en) * 2024-08-16 2026-02-19 Emeramed Limited N,n-bis-2-mercaptoethyl isophthalamide for use in the treatment of pain

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100227812A1 (en) * 2008-12-06 2010-09-09 Haley Boyd E Method of supplementing the diet and ameliorating oxidative stress

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586600B2 (en) 2000-12-06 2003-07-01 University Of Kentucky Research Foundation Multidentate sulfur-containing ligands
JP2011026204A (ja) * 2007-11-26 2011-02-10 Rei Furukawa タバコの煙を吸入することにより引き起こされる疾患の予防及び/又は治療用組成物
US8575218B2 (en) 2009-09-28 2013-11-05 The University Of Kentucky Research Foundation Thiol-containing compounds for the removal of elements from tissues and formulations therefor
CA2775397A1 (en) 2009-09-28 2011-03-31 University Of Kentucky Research Foundation Thiol-containing compounds for the removal of elements from contaminated milieu and methods of use
US20110237776A1 (en) 2010-03-25 2011-09-29 Haley Boyd E Aromatic compounds with sulfur containing ligands
US8426368B2 (en) * 2010-03-25 2013-04-23 The University Of Kentucky Research Foundation Method of ameliorating oxidative stress and supplementing the diet

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100227812A1 (en) * 2008-12-06 2010-09-09 Haley Boyd E Method of supplementing the diet and ameliorating oxidative stress

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATEL, R. B. et al. Toxicology Mechanisms and Methods (2012) vol. 22, no. 5, pages 383-396 *

Also Published As

Publication number Publication date
HUE036206T2 (hu) 2018-06-28
EA032116B1 (ru) 2019-04-30
US9782368B2 (en) 2017-10-10
GB201406115D0 (en) 2014-05-21
ME03012B (me) 2018-10-20
JP2017511307A (ja) 2017-04-20
PL3125876T3 (pl) 2018-05-30
NO3125876T3 (enExample) 2018-04-28
SG11201607478RA (en) 2016-10-28
PE20170586A1 (es) 2017-05-20
KR20160140929A (ko) 2016-12-07
CL2016002499A1 (es) 2017-01-27
CA2944113A1 (en) 2015-10-08
RS56905B1 (sr) 2018-05-31
UA119558C2 (uk) 2019-07-10
CA2944113C (en) 2022-06-21
GB2524831A (en) 2015-10-07
EA201692013A1 (ru) 2017-03-31
CN106132405A (zh) 2016-11-16
BR112016022880B1 (pt) 2022-09-13
EP3125876A1 (en) 2017-02-08
BR112016022880A2 (enExample) 2017-08-15
ES2659174T3 (es) 2018-03-14
KR102482699B1 (ko) 2022-12-28
SA516371966B1 (ar) 2019-04-14
SI3125876T1 (en) 2018-04-30
DK3125876T3 (en) 2018-01-15
JP6474423B2 (ja) 2019-02-27
LT3125876T (lt) 2018-02-12
IL248027B (en) 2019-03-31
PT3125876T (pt) 2018-02-22
SMT201800116T1 (it) 2018-03-08
MA39833A (fr) 2017-02-08
EP3125876B8 (en) 2018-01-24
US20170157072A1 (en) 2017-06-08
MA39833B1 (fr) 2018-04-30
CN106132405B (zh) 2019-06-18
MX2016012591A (es) 2017-04-06
ZA201606406B (en) 2018-04-25
CY1121235T1 (el) 2020-05-29
PH12016501975A1 (en) 2017-01-09
NZ724678A (en) 2022-12-23
AU2015242374A1 (en) 2016-10-13
HRP20180325T1 (hr) 2018-04-06
EP3125876B1 (en) 2017-11-29
ECSP16078100A (es) 2018-03-31
WO2015150793A1 (en) 2015-10-08

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