AU2014311358A1 - Treatment of pediatric otic disorders - Google Patents
Treatment of pediatric otic disorders Download PDFInfo
- Publication number
- AU2014311358A1 AU2014311358A1 AU2014311358A AU2014311358A AU2014311358A1 AU 2014311358 A1 AU2014311358 A1 AU 2014311358A1 AU 2014311358 A AU2014311358 A AU 2014311358A AU 2014311358 A AU2014311358 A AU 2014311358A AU 2014311358 A1 AU2014311358 A1 AU 2014311358A1
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- Prior art keywords
- composition
- ciprofloxacin
- middle ear
- treatment
- formulation
- Prior art date
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- 208000021510 thyroid gland disease Diseases 0.000 description 1
- 238000000954 titration curve Methods 0.000 description 1
- 229960000707 tobramycin Drugs 0.000 description 1
- NLVFBUXFDBBNBW-PBSUHMDJSA-N tobramycin Chemical compound N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N NLVFBUXFDBBNBW-PBSUHMDJSA-N 0.000 description 1
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- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0046—Ear
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
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- Dermatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| US201361870318P | 2013-08-27 | 2013-08-27 | |
| US61/870,318 | 2013-08-27 | ||
| US201361914904P | 2013-12-11 | 2013-12-11 | |
| US61/914,904 | 2013-12-11 | ||
| PCT/US2014/052754 WO2015031393A1 (en) | 2013-08-27 | 2014-08-26 | Treatment of pediatric otic disorders |
Publications (1)
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| AU2014311358A1 true AU2014311358A1 (en) | 2016-04-07 |
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| AU2014311358A Abandoned AU2014311358A1 (en) | 2013-08-27 | 2014-08-26 | Treatment of pediatric otic disorders |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9486405B2 (enExample) |
| EP (1) | EP3038707A4 (enExample) |
| JP (1) | JP2016534121A (enExample) |
| KR (1) | KR20160047490A (enExample) |
| CN (1) | CN105682742A (enExample) |
| AU (1) | AU2014311358A1 (enExample) |
| CA (1) | CA2921816A1 (enExample) |
| EA (1) | EA201690323A1 (enExample) |
| MX (1) | MX2016002408A (enExample) |
| WO (1) | WO2015031393A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US8318817B2 (en) | 2008-07-21 | 2012-11-27 | Otonomy, Inc. | Controlled release antimicrobial compositions and methods for the treatment of otic disorders |
| AU2015284048A1 (en) | 2014-07-03 | 2017-02-16 | Otonomy, Inc. | Sterilization of ciprofloxacin composition |
| EP3028721A1 (en) * | 2014-12-05 | 2016-06-08 | Exchange Imaging Technologies GmbH | Nanoparticle formulation having reverse-thermal gelation properties for injection |
| US11040004B2 (en) | 2016-09-16 | 2021-06-22 | Otonomy, Inc. | Otic gel formulations for treating otitis externa |
| EP3518929A4 (en) * | 2016-09-30 | 2020-05-06 | Otonomy, Inc. | OTIC GEL FORMULATIONS FOR THE TREATMENT OF OTITIS MEDIA |
| LT3737233T (lt) * | 2018-01-09 | 2025-11-25 | Augimo faktoriaus preparatai ausims | |
| US10561736B1 (en) | 2019-01-09 | 2020-02-18 | Spiral Therapeutics, Inc. | Apoptosis inhibitor formulations for prevention of hearing loss |
| WO2020223158A1 (en) * | 2019-04-30 | 2020-11-05 | The Medical College Of Wisconsin, Inc. | Trans-tympanic membrane delivery platform and uses thereof |
| TWI781536B (zh) | 2021-02-26 | 2022-10-21 | 國立臺灣科技大學 | 藥物釋放組合物、其製造方法及其用途 |
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-
2014
- 2014-08-26 US US14/469,408 patent/US9486405B2/en not_active Expired - Fee Related
- 2014-08-26 CN CN201480059041.6A patent/CN105682742A/zh active Pending
- 2014-08-26 WO PCT/US2014/052754 patent/WO2015031393A1/en not_active Ceased
- 2014-08-26 CA CA2921816A patent/CA2921816A1/en not_active Abandoned
- 2014-08-26 KR KR1020167006673A patent/KR20160047490A/ko not_active Withdrawn
- 2014-08-26 JP JP2016537779A patent/JP2016534121A/ja active Pending
- 2014-08-26 MX MX2016002408A patent/MX2016002408A/es unknown
- 2014-08-26 EP EP14840963.4A patent/EP3038707A4/en not_active Withdrawn
- 2014-08-26 AU AU2014311358A patent/AU2014311358A1/en not_active Abandoned
- 2014-08-26 EA EA201690323A patent/EA201690323A1/ru unknown
-
2016
- 2016-09-13 US US15/264,107 patent/US20170027930A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016534121A (ja) | 2016-11-04 |
| US9486405B2 (en) | 2016-11-08 |
| US20150290124A1 (en) | 2015-10-15 |
| US20170027930A1 (en) | 2017-02-02 |
| KR20160047490A (ko) | 2016-05-02 |
| MX2016002408A (es) | 2016-10-28 |
| EA201690323A1 (ru) | 2016-07-29 |
| WO2015031393A1 (en) | 2015-03-05 |
| CN105682742A (zh) | 2016-06-15 |
| EP3038707A4 (en) | 2017-03-01 |
| CA2921816A1 (en) | 2015-03-05 |
| EP3038707A1 (en) | 2016-07-06 |
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