AU2014225373B2 - Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis - Google Patents

Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis Download PDF

Info

Publication number
AU2014225373B2
AU2014225373B2 AU2014225373A AU2014225373A AU2014225373B2 AU 2014225373 B2 AU2014225373 B2 AU 2014225373B2 AU 2014225373 A AU2014225373 A AU 2014225373A AU 2014225373 A AU2014225373 A AU 2014225373A AU 2014225373 B2 AU2014225373 B2 AU 2014225373B2
Authority
AU
Australia
Prior art keywords
zoledronic acid
osteoarthritis
steroid
halogen
prednisolone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2014225373A
Other languages
English (en)
Other versions
AU2014225373A1 (en
Inventor
Ketan Desai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Levolta Pharmaceuticals Inc
Original Assignee
Levolta Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Levolta Pharmaceuticals Inc filed Critical Levolta Pharmaceuticals Inc
Publication of AU2014225373A1 publication Critical patent/AU2014225373A1/en
Application granted granted Critical
Publication of AU2014225373B2 publication Critical patent/AU2014225373B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2014225373A 2013-03-08 2014-03-07 Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis Active AU2014225373B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/791,685 US9012432B2 (en) 2013-03-08 2013-03-08 Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis
US13/791,685 2013-03-08
PCT/US2014/022169 WO2014138712A1 (en) 2013-03-08 2014-03-07 Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis

Publications (2)

Publication Number Publication Date
AU2014225373A1 AU2014225373A1 (en) 2015-10-22
AU2014225373B2 true AU2014225373B2 (en) 2018-07-05

Family

ID=51488530

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2014225373A Active AU2014225373B2 (en) 2013-03-08 2014-03-07 Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis

Country Status (12)

Country Link
US (1) US9012432B2 (https=)
EP (1) EP2964209B1 (https=)
JP (2) JP6839491B2 (https=)
KR (1) KR102253394B1 (https=)
CN (1) CN105324113B (https=)
AU (1) AU2014225373B2 (https=)
BR (1) BR112015021503B1 (https=)
CA (1) CA2941346C (https=)
EA (1) EA032067B1 (https=)
ES (1) ES2904365T3 (https=)
MX (1) MX377447B (https=)
WO (1) WO2014138712A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10913772B2 (en) 2016-03-09 2021-02-09 Kine Sciences Co., Ltd. Peptide for preventing or treating inflammatory diseases and use thereof
WO2017155234A1 (ko) 2016-03-09 2017-09-14 주식회사 바이오펩 염증성 질환의 예방 또는 치료용 펩타이드 및 이의 용도
US10913771B2 (en) 2016-03-09 2021-02-09 Kine Sciences Co., Ltd. Peptide for preventing or treating inflammatory diseases and use thereof
KR101897122B1 (ko) 2016-03-09 2018-09-10 주식회사 바이오펩 염증성 질환의 예방 또는 치료용 펩타이드 및 이의 용도
CN108431020B (zh) 2016-03-09 2022-03-29 凯恩塞恩斯株式会社 用于预防或治疗炎症性疾病的肽及其应用
JP7127616B2 (ja) 2019-06-04 2022-08-30 横河電機株式会社 情報処理装置、アラーム管理システム、及びアラーム管理方法
WO2021163432A1 (en) * 2020-02-12 2021-08-19 Levolta Pharmaceuticals, Inc. Co-administration of prednisolone/methyl prednisolone and zoledronic acid to treat and prevent osteoarthritis
CN114028571B (zh) * 2021-11-18 2023-04-28 中国医学科学院基础医学研究所 含氮双膦酸盐联合糖皮质激素在预防或治疗病毒性肺炎中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110263537A1 (en) * 2010-04-26 2011-10-27 Ketan Desai Co-administration of steroids and zoledronic acid to prevent and treat side effects from zoledronic acid infusion

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2038692T4 (es) 1986-11-21 2012-02-10 Novartis Ag Procedimiento para la obtencion de acidos alcanodifosfonicos substituidos.
US7018647B1 (en) * 1999-12-27 2006-03-28 Teikoku Seiyaku Co., Ltd Patches for external use
GB0029111D0 (en) * 2000-11-29 2001-01-10 Novartis Ag Organic compounds
EP1399162A2 (en) * 2001-06-08 2004-03-24 Ortho-McNeil Pharmaceutical, Inc. Treating neuropathic/inflammatory pain by targeting a composition (e.g. zd7288) to hcn pacemaker channels
AU2003226148A1 (en) * 2002-04-05 2003-10-27 Merck & Co., Inc. Method for inhibiting bone resorption with an alendronate and vitamin d formulation
CA2539359A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and a bisphosphonate
US20090035315A1 (en) * 2004-06-17 2009-02-05 Stephan Christgau Method of Improving Treatments in Rheumatic and Arthritic Diseases
JP5240925B2 (ja) * 2005-05-25 2013-07-17 カロシン ファーマ， インコーポレイテッド 変形性関節症を処置するための方法および組成物
US20070048372A1 (en) * 2005-08-18 2007-03-01 Srz Properties, Inc. Method for treating non-inflammatory osteoarthritic pain
UA96457C2 (ru) * 2006-08-03 2011-11-10 Нитек Фарма Аг Лечение ревматоидного артрита глюкокортикоидами с отсроченным высвобождением
US20100158905A1 (en) * 2008-12-19 2010-06-24 Nuon Therapeutics, Inc. Combination therapy of arthritis with tranilast
CN102427792A (zh) * 2009-05-04 2012-04-25 扎斯制药公司 治疗与神经瘤、神经卡压及其他病况相关联的疼痛的方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110263537A1 (en) * 2010-04-26 2011-10-27 Ketan Desai Co-administration of steroids and zoledronic acid to prevent and treat side effects from zoledronic acid infusion

Also Published As

Publication number Publication date
US20140256681A1 (en) 2014-09-11
CN105324113B (zh) 2018-07-03
MX2015011671A (es) 2016-05-12
JP2019104762A (ja) 2019-06-27
JP2016510765A (ja) 2016-04-11
AU2014225373A1 (en) 2015-10-22
EA201591638A1 (ru) 2016-02-29
WO2014138712A1 (en) 2014-09-12
EA032067B1 (ru) 2019-04-30
ES2904365T3 (es) 2022-04-04
MX377447B (es) 2025-03-10
BR112015021503B1 (pt) 2022-09-06
BR112015021503A2 (en) 2018-05-15
JP6839491B2 (ja) 2021-03-17
EP2964209A1 (en) 2016-01-13
US9012432B2 (en) 2015-04-21
KR20150125001A (ko) 2015-11-06
KR102253394B1 (ko) 2021-05-20
EP2964209A4 (en) 2016-08-03
CN105324113A (zh) 2016-02-10
CA2941346C (en) 2020-03-10
EP2964209B1 (en) 2021-10-27
CA2941346A1 (en) 2014-09-12

Similar Documents

Publication Publication Date Title
US9737553B2 (en) Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis
AU2014225373B2 (en) Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis
Yamazaki et al. Remarkable response of juvenile diffuse sclerosing osteomyelitis of mandible to pamidronate
MX2012014428A (es) Administracion de profarmacos activados por hipoxia y de agentes antiangiogenicos para el tratamiento de cancer.
Meulenbeld et al. Randomised phase II/III study of docetaxel with or without risedronate in patients with metastatic Castration Resistant Prostate Cancer (CRPC), the Netherlands Prostate Study (NePro)
US20110263537A1 (en) Co-administration of steroids and zoledronic acid to prevent and treat side effects from zoledronic acid infusion
Dickinson et al. Osteonecrosis of the jaw complicating bisphosphonate treatment for bone disease in multiple myeloma: an overview with recommendations for prevention and treatment
CN104203232A (zh) 用于抗肿瘤试剂施用的方法
EP3988175A1 (en) Method for treating malignant tumor
Body Treatment and prevention of bone metastases and myeloma bone disease
WO2021163432A1 (en) Co-administration of prednisolone/methyl prednisolone and zoledronic acid to treat and prevent osteoarthritis
US20200360544A1 (en) Radioactive antitumor agent
Li et al. Infusion of ibandronate once every 3 months effectively decreases bone resorption markers and increases bone mineral density in Chinese postmenopausal osteoporotic women: a 1-year study
IT202100009926A1 (it) Una combinazione comprendente un inibitore di hdac6 specifico e almeno un inibitore del checkpoint ctla4
Pitarokoili et al. Dimethyl fumarate for patients with neuromyelitis optica spectrum disorder.
US20250177352A1 (en) Combination treatment for cancer
HK1217918A1 (zh) 用於治疗何杰金氏淋巴瘤的4-氰基-n-(2-(4，4-二甲基环己-1-烯-1-基)-6-(2，2，6，6-四甲基四氢-2h-吡喃-4-基)吡啶-3-基)-1h-咪唑-2-酰胺
JP2022508692A (ja) 転移性前立腺がんを処置するための併用療法
AU2019204559B2 (en) Osteoclast inhibitors for pain
Hossain et al. Effect of single dose intravenous zoledronic acid on bone mineral density in post-menopausal osteoporosis of Bangladeshi women
Von Tresckow et al. A phase 1 study of JNJ-40346527, a colony stimulating factor-1 receptor (CSF-1R) inhibitor, in patients with relapsed or refractory Hodgkin lymphoma
KR20210038700A (ko) 통증용 파골 세포 억제제
Mark et al. Are Bone Targeted Agents Still Useful in Times of Immunotherapy? The Sakk 80/19 Bta Study
Farrell Benefits of denosumab in treating bone metastases.

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)