AU2013366464B2 - Test device for electrochemical analysis - Google Patents

Test device for electrochemical analysis Download PDF

Info

Publication number
AU2013366464B2
AU2013366464B2 AU2013366464A AU2013366464A AU2013366464B2 AU 2013366464 B2 AU2013366464 B2 AU 2013366464B2 AU 2013366464 A AU2013366464 A AU 2013366464A AU 2013366464 A AU2013366464 A AU 2013366464A AU 2013366464 B2 AU2013366464 B2 AU 2013366464B2
Authority
AU
Australia
Prior art keywords
conductive
oxidase
group
poly
conductive polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2013366464A
Other languages
English (en)
Other versions
AU2013366464A1 (en
Inventor
John Anthony Bolbot
Anthony BOYLAN
Manus Joseph Dennison
Jerome Mcaleer
Christopher John Slevin
David William Taylor
Murray John WHYTE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alere Switzerland GmbH
Original Assignee
Alere Switzerland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alere Switzerland GmbH filed Critical Alere Switzerland GmbH
Publication of AU2013366464A1 publication Critical patent/AU2013366464A1/en
Application granted granted Critical
Publication of AU2013366464B2 publication Critical patent/AU2013366464B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/38—[b, e]-condensed with two six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/36—[b, e]-condensed, at least one with a further condensed benzene ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G01N33/561—Immunoelectrophoresis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3273—Devices therefor, e.g. test element readers, circuitry
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E60/00—Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
    • Y02E60/30—Hydrogen technology
    • Y02E60/50—Fuel cells

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2013366464A 2012-12-21 2013-12-20 Test device for electrochemical analysis Ceased AU2013366464B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261745211P 2012-12-21 2012-12-21
GB1223166.8 2012-12-21
US61/745,211 2012-12-21
GBGB1223166.8A GB201223166D0 (en) 2012-12-21 2012-12-21 Test strip
US201361770233P 2013-02-27 2013-02-27
US61/770,233 2013-02-27
PCT/EP2013/077797 WO2014096407A1 (en) 2012-12-21 2013-12-20 Test device for electrochemical analysis

Publications (2)

Publication Number Publication Date
AU2013366464A1 AU2013366464A1 (en) 2015-08-06
AU2013366464B2 true AU2013366464B2 (en) 2017-05-25

Family

ID=47682396

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013366464A Ceased AU2013366464B2 (en) 2012-12-21 2013-12-20 Test device for electrochemical analysis

Country Status (9)

Country Link
US (1) US20150330935A1 (enExample)
EP (1) EP2938602A1 (enExample)
JP (1) JP2016500447A (enExample)
KR (1) KR20150097692A (enExample)
CN (2) CN107941865A (enExample)
AU (1) AU2013366464B2 (enExample)
GB (2) GB201223166D0 (enExample)
HK (2) HK1213568A1 (enExample)
WO (1) WO2014096407A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101740034B1 (ko) 2015-07-20 2017-06-08 주식회사 아이센스 베타-히드록시부틸레이트 검출을 위한 산화환원 시약 조성물, 및 상기시약 조성물을 포함하는 전기화학적 바이오센서
JP2017036951A (ja) * 2015-08-07 2017-02-16 ソニー株式会社 カートリッジ、検出装置及び検出方法
AU2016383525A1 (en) * 2015-12-28 2018-05-31 Lifescan Scotland Limited Electrochemical-based analytical test strip with electrode voltage sensing connections and hand-held test meter for use therewith
KR102290253B1 (ko) 2016-07-11 2021-08-20 삼성전자주식회사 바이오 센서 및 그의 제작 방법
CN106596693B (zh) * 2016-11-30 2019-03-29 中国科学院上海应用物理研究所 一种用于肌氨酸的电化学检测方法
CN107478707A (zh) * 2017-07-13 2017-12-15 大连大学 一种用于血糖测定的新型电极及其测定方法
EP3480595A1 (en) * 2017-11-02 2019-05-08 Elisha Systems Ltd. Biosensor manufacture
CN109781989A (zh) * 2017-11-10 2019-05-21 上海瀚联医疗技术股份有限公司 血糖测试的方法及生物传感器
CN109781821B (zh) * 2017-11-10 2023-10-24 上海瀚联医疗技术股份有限公司 一种血糖检测仪
CN109781804A (zh) * 2017-11-10 2019-05-21 上海瀚联医疗技术股份有限公司 一种血糖测试模块
US12144614B2 (en) 2018-01-18 2024-11-19 King Abdullah University Of Science And Technology N-type polymer based electrochemical device for direct enzymatic metabolite sensing and methods of making and using
WO2019224628A1 (en) * 2018-05-21 2019-11-28 King Abdullah University Of Science And Technology Inkjet-printed electrochemical metabolite sensors
CN109507250A (zh) * 2019-01-16 2019-03-22 威海纽普生物技术有限公司 检测d二聚体的电化学试剂盒及其制备方法
EP4007911A1 (en) 2019-08-03 2022-06-08 King Abdullah University Of Science And Technology Device for detecting analytes in a sample, and methods of use thereof
KR102248653B1 (ko) * 2020-02-24 2021-05-04 성균관대학교산학협력단 가변저항소자, 이의 제조 방법 및 이를 포함하는 수위센서
KR20210112137A (ko) * 2020-03-04 2021-09-14 동우 화인켐 주식회사 전기화학센서 및 이의 제조방법
KR20210116889A (ko) 2020-03-18 2021-09-28 동우 화인켐 주식회사 바이오센서
CN114632559B (zh) * 2022-01-26 2023-03-31 浙江大学 基于电阻抗检测的片上微槽阵列数字pcr芯片及制作方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0775699A1 (en) * 1995-11-22 1997-05-28 Bayer Corporation Method for the preparation of substituted 3-(phenylimino)-3H-phenothiazines and phenoxazines
WO2005040407A1 (en) * 2003-10-24 2005-05-06 Bayer Healthcare Llc Enzymatic electrochemical biosensor
WO2009076268A1 (en) * 2007-12-10 2009-06-18 Bayer Healthcare Llc Process of making 3-phenylimino-3h-phenothiazine or 3-phenylimino-3h-phenoxazine mediator

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4938860A (en) * 1985-06-28 1990-07-03 Miles Inc. Electrode for electrochemical sensors
ES2075955T3 (es) * 1989-12-15 1995-10-16 Boehringer Mannheim Corp Reactivo mediador redox y biosensor.
US6033866A (en) * 1997-12-08 2000-03-07 Biomedix, Inc. Highly sensitive amperometric bi-mediator-based glucose biosensor
EP2388587B1 (en) * 2000-11-30 2018-01-10 Panasonic Healthcare Holdings Co., Ltd. Method of quantifying substrate
JP4103030B2 (ja) * 2002-02-19 2008-06-18 日立化成工業株式会社 相分離型樹脂組成物、相分離型樹脂フィルム及び相分離型樹脂組成物付き回路基板の製造方法
JP2006058289A (ja) * 2004-07-23 2006-03-02 Canon Inc 酵素電極、センサ、燃料電池、電気化学反応装置
JP4972956B2 (ja) * 2006-02-27 2012-07-11 住友電気工業株式会社 バイオセンサシステム及びその測定器
JP5395665B2 (ja) * 2006-09-22 2014-01-22 バイエル・ヘルスケア・エルエルシー 改善された安定性およびヘマトクリット性能（ｐｅｒｆｏｒｍａｎｃｅ）を有するバイオセンサー系
CN101535476B (zh) * 2006-11-14 2012-10-24 东洋纺织株式会社 修饰型黄素腺嘌呤二核苷酸依赖性葡萄糖脱氢酶
JP5405916B2 (ja) * 2008-06-24 2014-02-05 パナソニック株式会社 バイオセンサ、その製造方法、及びそれを備える検出システム
US8696917B2 (en) * 2009-02-09 2014-04-15 Edwards Lifesciences Corporation Analyte sensor and fabrication methods
WO2011012754A2 (es) * 2009-07-30 2011-02-03 Fundacion Cidetec Sensor electroquímico para la detección de analitos en medios líquidos
WO2013086007A2 (en) * 2011-12-09 2013-06-13 Abbott Diabetes Care Inc. Electrodes with conductive polymer underlayer
EP2840144A1 (en) * 2013-08-20 2015-02-25 Roche Diagniostics GmbH A method for making a dry sensor element for an enzymatic determination of an analyte in a body fluid, a dry sensor element and article

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0775699A1 (en) * 1995-11-22 1997-05-28 Bayer Corporation Method for the preparation of substituted 3-(phenylimino)-3H-phenothiazines and phenoxazines
WO2005040407A1 (en) * 2003-10-24 2005-05-06 Bayer Healthcare Llc Enzymatic electrochemical biosensor
WO2009076268A1 (en) * 2007-12-10 2009-06-18 Bayer Healthcare Llc Process of making 3-phenylimino-3h-phenothiazine or 3-phenylimino-3h-phenoxazine mediator

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
J.A. VANALLAN ET AL: "POLYNUCLEAR HETEROCYCLES. I. 1H-BENZO SUBSTANCES 1a" JOURNAL OF ORGANIC CHEMISTRY, VOL 27, NO 5, 01 MAY 1962, PP1659-1664 *
JAMES A. VANALLAN ET AL: "REACTION OF 12H-BENZO PHENOTHIAZINE AND 12H-BENZO HETEROCYCLIC AZIDES" THE JOURNAL OF ORGANIC CHEMISTRY, VOL 34, NO 6, 01 JUNE 1969, PP 1691 - 1694 *

Also Published As

Publication number Publication date
US20150330935A1 (en) 2015-11-19
HK1214360A1 (zh) 2016-07-22
GB201410773D0 (en) 2014-07-30
AU2013366464A1 (en) 2015-08-06
JP2016500447A (ja) 2016-01-12
HK1213568A1 (zh) 2016-07-08
GB201223166D0 (en) 2013-02-06
KR20150097692A (ko) 2015-08-26
EP2938602A1 (en) 2015-11-04
CN104918925B (zh) 2017-11-14
CN104918925A (zh) 2015-09-16
WO2014096407A1 (en) 2014-06-26
CN107941865A (zh) 2018-04-20
GB2523419A (en) 2015-08-26

Similar Documents

Publication Publication Date Title
AU2013366464B2 (en) Test device for electrochemical analysis
US11162916B2 (en) Accurate analyte measurements for electrochemical test strip based on sensed physical characteristic(s) of the sample containing the analyte
JP5066108B2 (ja) サンプル中の検体を測定するシステムおよび方法
JP3553884B2 (ja) 非浸出性または拡散性の酸化還元媒介剤を用いた小体積生体外分析物センサー
US8007656B2 (en) Enzymatic electrochemical biosensor
US9835578B2 (en) Temperature compensation for an analyte measurement determined from a specified sampling time derived from a sensed physical characteristic of the sample containing the analyte
BRPI0717430A2 (pt) Sistema de biossensor tendo estabilidade e desempenho de hematócritos maiores
AU2007201378A1 (en) Methods and apparatus for analyzing a sample in the presence of interferents
CA2973124A1 (en) Concentration determination in a diffusion barrier layer
CA2713804A1 (en) Multi-analyte test strip with shared counter/reference electrode and inline electrode configuration
US20160069832A1 (en) Co-facial analytical test strip with stacked unidirectional contact pads
ES2555215T3 (es) Composiciones de reactivo de bajo contenido salino total y sistemas para biosensores
US20050089944A1 (en) High sensitivity amperometric biosensor with side-to-side hybrid configuration
EP2270495A2 (en) Analyte test strip with combination electrode contact and meter identification feature
KR20060048711A (ko) 산화환원 시약 시스템 효소를 특징으로 하는 방법 및조성물
AU2016202064B2 (en) Concentration determination in a diffusion barrier layer
HK1151857A (en) Analyte test strip with combination electrode contact and meter identification feature

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired