AU2013317842A1 - Multilayer biodegradable microparticles for sustained release of therapeutic agents - Google Patents

Multilayer biodegradable microparticles for sustained release of therapeutic agents Download PDF

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Publication number
AU2013317842A1
AU2013317842A1 AU2013317842A AU2013317842A AU2013317842A1 AU 2013317842 A1 AU2013317842 A1 AU 2013317842A1 AU 2013317842 A AU2013317842 A AU 2013317842A AU 2013317842 A AU2013317842 A AU 2013317842A AU 2013317842 A1 AU2013317842 A1 AU 2013317842A1
Authority
AU
Australia
Prior art keywords
composition
polymer
solvent
poly
layers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2013317842A
Other languages
English (en)
Inventor
Robert Jennings
Reddy LAXMA
Nikita MALAVIA
Betty NORMAN
Chris Rhodes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OHR Pharma LLC
Original Assignee
OHR Pharma LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by OHR Pharma LLC filed Critical OHR Pharma LLC
Publication of AU2013317842A1 publication Critical patent/AU2013317842A1/en
Priority to AU2018205060A priority Critical patent/AU2018205060A1/en
Priority to AU2020202040A priority patent/AU2020202040A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2013317842A 2012-09-20 2013-09-20 Multilayer biodegradable microparticles for sustained release of therapeutic agents Abandoned AU2013317842A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2018205060A AU2018205060A1 (en) 2012-09-20 2018-07-09 Multilayer Biodegradable Microparticles For Sustained Release of Therapeutic Agents
AU2020202040A AU2020202040A1 (en) 2012-09-20 2020-03-20 Multilayer Biodegradable Microparticles For Sustained Release of Therapeutic Agents

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261703743P 2012-09-20 2012-09-20
US61/703,743 2012-09-20
PCT/US2013/060987 WO2014047477A2 (en) 2012-09-20 2013-09-20 Multilayer biodegradable microparticles for sustained release of therapeutic agents

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2018205060A Division AU2018205060A1 (en) 2012-09-20 2018-07-09 Multilayer Biodegradable Microparticles For Sustained Release of Therapeutic Agents

Publications (1)

Publication Number Publication Date
AU2013317842A1 true AU2013317842A1 (en) 2015-04-30

Family

ID=50342085

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2013317842A Abandoned AU2013317842A1 (en) 2012-09-20 2013-09-20 Multilayer biodegradable microparticles for sustained release of therapeutic agents
AU2018205060A Abandoned AU2018205060A1 (en) 2012-09-20 2018-07-09 Multilayer Biodegradable Microparticles For Sustained Release of Therapeutic Agents
AU2020202040A Abandoned AU2020202040A1 (en) 2012-09-20 2020-03-20 Multilayer Biodegradable Microparticles For Sustained Release of Therapeutic Agents

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2018205060A Abandoned AU2018205060A1 (en) 2012-09-20 2018-07-09 Multilayer Biodegradable Microparticles For Sustained Release of Therapeutic Agents
AU2020202040A Abandoned AU2020202040A1 (en) 2012-09-20 2020-03-20 Multilayer Biodegradable Microparticles For Sustained Release of Therapeutic Agents

Country Status (9)

Country Link
US (2) US20140093552A1 (enExample)
EP (1) EP2897597B1 (enExample)
JP (2) JP2015529255A (enExample)
KR (1) KR20150083841A (enExample)
AU (3) AU2013317842A1 (enExample)
BR (1) BR112015006141A2 (enExample)
HK (1) HK1213178A1 (enExample)
MX (1) MX2015003658A (enExample)
WO (1) WO2014047477A2 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2974348A1 (en) * 2015-01-19 2016-07-28 The Regents Of The University Of Michigan Multiphasic particles fabricated by wettability engendered templated self-assembly (wets) methods
CN115920125B (zh) * 2022-11-30 2024-07-26 爱美客技术发展股份有限公司 一种复合凝胶及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5490962A (en) * 1993-10-18 1996-02-13 Massachusetts Institute Of Technology Preparation of medical devices by solid free-form fabrication methods
SE9803871D0 (sv) * 1998-11-11 1998-11-11 Pharmacia & Upjohn Ab Therapeutic method and formulation
WO2004096896A2 (en) * 2002-09-06 2004-11-11 Hansford Derek J Microfabrication of polymer microparticles
JP4547888B2 (ja) * 2003-10-10 2010-09-22 小野薬品工業株式会社 胃内浮遊性固形製剤
CA2700356C (en) * 2007-09-27 2013-07-09 Akina, Inc. Sol-gel phase-reversible hydrogel templates and uses thereof
JP2010001248A (ja) * 2008-06-20 2010-01-07 Bioserentack Co Ltd 酢酸リュープロレインの徐放性ミリ、マイクロカプセル
US20110256218A1 (en) * 2010-01-04 2011-10-20 Eurand, Inc. Controlled release compositions comprising meclizine or related piperazine derivatives
US8697117B2 (en) * 2010-08-02 2014-04-15 Ramot At Tel-Aviv University Ltd. Drug-eluting films

Also Published As

Publication number Publication date
JP2015529255A (ja) 2015-10-05
EP2897597A2 (en) 2015-07-29
US20140093552A1 (en) 2014-04-03
EP2897597B1 (en) 2020-07-08
AU2018205060A1 (en) 2018-07-26
BR112015006141A2 (pt) 2019-11-19
HK1213178A1 (zh) 2016-06-30
JP2019089824A (ja) 2019-06-13
MX2015003658A (es) 2015-09-25
WO2014047477A3 (en) 2014-06-19
KR20150083841A (ko) 2015-07-20
US20170354611A1 (en) 2017-12-14
EP2897597A4 (en) 2016-05-11
AU2020202040A1 (en) 2020-04-09
WO2014047477A2 (en) 2014-03-27

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted