HK1213178A1 - 用於治疗剂的缓释的多层生物可降解的微粒 - Google Patents

用於治疗剂的缓释的多层生物可降解的微粒 Download PDF

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Publication number
HK1213178A1
HK1213178A1 HK16101089.2A HK16101089A HK1213178A1 HK 1213178 A1 HK1213178 A1 HK 1213178A1 HK 16101089 A HK16101089 A HK 16101089A HK 1213178 A1 HK1213178 A1 HK 1213178A1
Authority
HK
Hong Kong
Prior art keywords
composition
solvent
polymer
therapeutic agents
sustained release
Prior art date
Application number
HK16101089.2A
Other languages
English (en)
Chinese (zh)
Inventor
Chris Rhodes
Nikita MALAVIA
Robert Jennings
Reddy LAXMA
Betty NORMAN
Original Assignee
Ohr Pharma, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ohr Pharma, Llc filed Critical Ohr Pharma, Llc
Publication of HK1213178A1 publication Critical patent/HK1213178A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK16101089.2A 2012-09-20 2013-09-20 用於治疗剂的缓释的多层生物可降解的微粒 HK1213178A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261703743P 2012-09-20 2012-09-20
US61/703,743 2012-09-20
PCT/US2013/060987 WO2014047477A2 (en) 2012-09-20 2013-09-20 Multilayer biodegradable microparticles for sustained release of therapeutic agents

Publications (1)

Publication Number Publication Date
HK1213178A1 true HK1213178A1 (zh) 2016-06-30

Family

ID=50342085

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16101089.2A HK1213178A1 (zh) 2012-09-20 2013-09-20 用於治疗剂的缓释的多层生物可降解的微粒

Country Status (9)

Country Link
US (2) US20140093552A1 (enExample)
EP (1) EP2897597B1 (enExample)
JP (2) JP2015529255A (enExample)
KR (1) KR20150083841A (enExample)
AU (3) AU2013317842A1 (enExample)
BR (1) BR112015006141A2 (enExample)
HK (1) HK1213178A1 (enExample)
MX (1) MX2015003658A (enExample)
WO (1) WO2014047477A2 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2974348A1 (en) * 2015-01-19 2016-07-28 The Regents Of The University Of Michigan Multiphasic particles fabricated by wettability engendered templated self-assembly (wets) methods
CN115920125B (zh) * 2022-11-30 2024-07-26 爱美客技术发展股份有限公司 一种复合凝胶及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5490962A (en) * 1993-10-18 1996-02-13 Massachusetts Institute Of Technology Preparation of medical devices by solid free-form fabrication methods
SE9803871D0 (sv) * 1998-11-11 1998-11-11 Pharmacia & Upjohn Ab Therapeutic method and formulation
US20040115279A1 (en) * 2002-09-06 2004-06-17 The Ohio State University Microfabrication of polymer microparticles
JP4547888B2 (ja) * 2003-10-10 2010-09-22 小野薬品工業株式会社 胃内浮遊性固形製剤
EP2198302B1 (en) * 2007-09-27 2017-09-27 Samyang Biopharmaceuticals Corporation Sol-gel phase-reversible hydrogel templates and uses thereof
JP2010001248A (ja) * 2008-06-20 2010-01-07 Bioserentack Co Ltd 酢酸リュープロレインの徐放性ミリ、マイクロカプセル
WO2011082426A1 (en) * 2010-01-04 2011-07-07 Eurand, Inc. Controlled release compositions comprising meclizine or related piperazine derivatives
US8697117B2 (en) * 2010-08-02 2014-04-15 Ramot At Tel-Aviv University Ltd. Drug-eluting films

Also Published As

Publication number Publication date
AU2018205060A1 (en) 2018-07-26
BR112015006141A2 (pt) 2019-11-19
US20170354611A1 (en) 2017-12-14
MX2015003658A (es) 2015-09-25
JP2019089824A (ja) 2019-06-13
EP2897597A4 (en) 2016-05-11
JP2015529255A (ja) 2015-10-05
WO2014047477A3 (en) 2014-06-19
EP2897597B1 (en) 2020-07-08
WO2014047477A2 (en) 2014-03-27
US20140093552A1 (en) 2014-04-03
EP2897597A2 (en) 2015-07-29
KR20150083841A (ko) 2015-07-20
AU2020202040A1 (en) 2020-04-09
AU2013317842A1 (en) 2015-04-30

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