AU2013245830A1 - Cartilage repair, preservation and growth by stimulation of bone-chondral interphase and delivery system and related methods therefor - Google Patents
Cartilage repair, preservation and growth by stimulation of bone-chondral interphase and delivery system and related methods therefor Download PDFInfo
- Publication number
- AU2013245830A1 AU2013245830A1 AU2013245830A AU2013245830A AU2013245830A1 AU 2013245830 A1 AU2013245830 A1 AU 2013245830A1 AU 2013245830 A AU2013245830 A AU 2013245830A AU 2013245830 A AU2013245830 A AU 2013245830A AU 2013245830 A1 AU2013245830 A1 AU 2013245830A1
- Authority
- AU
- Australia
- Prior art keywords
- delivery device
- exemplary
- bone
- cap
- prp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000034 method Methods 0.000 title claims abstract description 48
- 210000000845 cartilage Anatomy 0.000 title claims abstract description 36
- 230000008439 repair process Effects 0.000 title claims abstract description 24
- 238000004321 preservation Methods 0.000 title claims abstract description 6
- 230000016507 interphase Effects 0.000 title description 11
- 230000000638 stimulation Effects 0.000 title description 4
- 239000003814 drug Substances 0.000 claims abstract description 38
- 238000005520 cutting process Methods 0.000 claims abstract description 23
- 230000001225 therapeutic effect Effects 0.000 claims abstract description 16
- 210000000988 bone and bone Anatomy 0.000 claims description 51
- 210000003127 knee Anatomy 0.000 claims description 40
- 210000004623 platelet-rich plasma Anatomy 0.000 claims description 39
- 238000002347 injection Methods 0.000 claims description 26
- 239000007924 injection Substances 0.000 claims description 26
- 102100039619 Granulocyte colony-stimulating factor Human genes 0.000 claims description 15
- 101000746367 Homo sapiens Granulocyte colony-stimulating factor Proteins 0.000 claims description 15
- 210000001519 tissue Anatomy 0.000 claims description 11
- 238000005553 drilling Methods 0.000 claims description 10
- 230000001054 cortical effect Effects 0.000 claims description 8
- 238000002594 fluoroscopy Methods 0.000 claims description 6
- 230000002093 peripheral effect Effects 0.000 claims description 6
- 206010053567 Coagulopathies Diseases 0.000 claims description 5
- 210000004369 blood Anatomy 0.000 claims description 5
- 239000008280 blood Substances 0.000 claims description 5
- 230000035602 clotting Effects 0.000 claims description 5
- 238000010079 rubber tapping Methods 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 238000003384 imaging method Methods 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 3
- 238000002604 ultrasonography Methods 0.000 claims description 3
- 230000004936 stimulating effect Effects 0.000 claims description 2
- 108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 claims 2
- 102000004269 Granulocyte Colony-Stimulating Factor Human genes 0.000 claims 2
- 238000009987 spinning Methods 0.000 claims 1
- 238000011282 treatment Methods 0.000 abstract description 19
- 208000014674 injury Diseases 0.000 abstract description 9
- 238000002560 therapeutic procedure Methods 0.000 abstract description 8
- 210000003484 anatomy Anatomy 0.000 abstract description 7
- 230000008733 trauma Effects 0.000 abstract description 7
- 210000000629 knee joint Anatomy 0.000 description 14
- 210000001185 bone marrow Anatomy 0.000 description 12
- 210000004027 cell Anatomy 0.000 description 10
- 210000001503 joint Anatomy 0.000 description 10
- 210000000130 stem cell Anatomy 0.000 description 10
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 9
- 229940079593 drug Drugs 0.000 description 9
- 210000004394 hip joint Anatomy 0.000 description 7
- 229910001220 stainless steel Inorganic materials 0.000 description 7
- 239000010935 stainless steel Substances 0.000 description 7
- 238000013459 approach Methods 0.000 description 6
- 229910001628 calcium chloride Inorganic materials 0.000 description 6
- 239000001110 calcium chloride Substances 0.000 description 6
- 210000001624 hip Anatomy 0.000 description 6
- 229910052751 metal Inorganic materials 0.000 description 6
- 239000002184 metal Substances 0.000 description 6
- 229940124597 therapeutic agent Drugs 0.000 description 6
- 208000013201 Stress fracture Diseases 0.000 description 5
- 108090000190 Thrombin Proteins 0.000 description 5
- 230000007547 defect Effects 0.000 description 5
- 208000015181 infectious disease Diseases 0.000 description 5
- 230000002980 postoperative effect Effects 0.000 description 5
- 229960004072 thrombin Drugs 0.000 description 5
- 210000000689 upper leg Anatomy 0.000 description 5
- 239000003570 air Substances 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 230000006378 damage Effects 0.000 description 4
- 230000003412 degenerative effect Effects 0.000 description 4
- 208000028867 ischemia Diseases 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 3
- 102000055008 Matrilin Proteins Human genes 0.000 description 3
- 108010072582 Matrilin Proteins Proteins 0.000 description 3
- 239000012080 ambient air Substances 0.000 description 3
- 210000004271 bone marrow stromal cell Anatomy 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 229920002674 hyaluronan Polymers 0.000 description 3
- 229960003160 hyaluronic acid Drugs 0.000 description 3
- 210000002901 mesenchymal stem cell Anatomy 0.000 description 3
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 description 3
- 201000008482 osteoarthritis Diseases 0.000 description 3
- 238000002203 pretreatment Methods 0.000 description 3
- 210000005065 subchondral bone plate Anatomy 0.000 description 3
- 210000002303 tibia Anatomy 0.000 description 3
- 108010071942 Colony-Stimulating Factors Proteins 0.000 description 2
- 102000007644 Colony-Stimulating Factors Human genes 0.000 description 2
- 208000002193 Pain Diseases 0.000 description 2
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 210000000588 acetabulum Anatomy 0.000 description 2
- 210000000577 adipose tissue Anatomy 0.000 description 2
- 230000004075 alteration Effects 0.000 description 2
- 206010003246 arthritis Diseases 0.000 description 2
- 210000001188 articular cartilage Anatomy 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 210000001612 chondrocyte Anatomy 0.000 description 2
- 229940047120 colony stimulating factors Drugs 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 210000001671 embryonic stem cell Anatomy 0.000 description 2
- 210000000968 fibrocartilage Anatomy 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 210000003714 granulocyte Anatomy 0.000 description 2
- 210000003035 hyaline cartilage Anatomy 0.000 description 2
- 239000007943 implant Substances 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 238000013150 knee replacement Methods 0.000 description 2
- 230000000670 limiting effect Effects 0.000 description 2
- 238000002483 medication Methods 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 230000036961 partial effect Effects 0.000 description 2
- 230000037361 pathway Effects 0.000 description 2
- 210000003314 quadriceps muscle Anatomy 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 230000002829 reductive effect Effects 0.000 description 2
- 230000008929 regeneration Effects 0.000 description 2
- 238000011069 regeneration method Methods 0.000 description 2
- 230000002441 reversible effect Effects 0.000 description 2
- 210000004872 soft tissue Anatomy 0.000 description 2
- 210000000707 wrist Anatomy 0.000 description 2
- 208000006820 Arthralgia Diseases 0.000 description 1
- 208000030016 Avascular necrosis Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 108010029961 Filgrastim Proteins 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010061246 Intervertebral disc degeneration Diseases 0.000 description 1
- 208000003947 Knee Osteoarthritis Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010031264 Osteonecrosis Diseases 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 208000008469 Peptic Ulcer Diseases 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 241000219061 Rheum Species 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- NRTOMJZYCJJWKI-UHFFFAOYSA-N Titanium nitride Chemical compound [Ti]#N NRTOMJZYCJJWKI-UHFFFAOYSA-N 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229960000074 biopharmaceutical Drugs 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 208000015100 cartilage disease Diseases 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 238000011443 conventional therapy Methods 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 229940111134 coxibs Drugs 0.000 description 1
- 239000003255 cyclooxygenase 2 inhibitor Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 208000018180 degenerative disc disease Diseases 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 210000004700 fetal blood Anatomy 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 210000000527 greater trochanter Anatomy 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 210000003090 iliac artery Anatomy 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 208000021600 intervertebral disc degenerative disease Diseases 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000003754 machining Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229940029345 neupogen Drugs 0.000 description 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000003349 osteoarthritic effect Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 208000011906 peptic ulcer disease Diseases 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
- 208000037804 stenosis Diseases 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/34—Trocars; Puncturing needles
- A61B17/3472—Trocars; Puncturing needles for bones, e.g. intraosseus injections
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261686835P | 2012-04-11 | 2012-04-11 | |
| US61/686,835 | 2012-04-11 | ||
| US201361800574P | 2013-03-15 | 2013-03-15 | |
| US61/800,574 | 2013-03-15 | ||
| PCT/US2013/036259 WO2013155359A1 (en) | 2012-04-11 | 2013-04-11 | Cartilage repair, preservation and growth by stimulation of bone-chondral interphase and delivery system and related methods therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2013245830A1 true AU2013245830A1 (en) | 2014-11-27 |
Family
ID=49328178
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2013245830A Abandoned AU2013245830A1 (en) | 2012-04-11 | 2013-04-11 | Cartilage repair, preservation and growth by stimulation of bone-chondral interphase and delivery system and related methods therefor |
Country Status (15)
| Country | Link |
|---|---|
| US (5) | US9827010B2 (https=) |
| EP (1) | EP2836147B1 (https=) |
| JP (2) | JP2015519100A (https=) |
| KR (1) | KR20150037738A (https=) |
| CN (1) | CN104661606B (https=) |
| AU (1) | AU2013245830A1 (https=) |
| CA (1) | CA2870203A1 (https=) |
| ES (1) | ES2772031T3 (https=) |
| HK (1) | HK1207552A1 (https=) |
| IL (1) | IL235156A0 (https=) |
| IN (1) | IN2014DN09449A (https=) |
| MX (1) | MX2014012205A (https=) |
| NZ (1) | NZ701804A (https=) |
| RU (1) | RU2014145346A (https=) |
| WO (1) | WO2013155359A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150037738A (ko) | 2012-04-11 | 2015-04-08 | 비자이 바드 | 골-연골 간기의 자극에 의한 연골 치유, 보존 및 성장, 및 이를 위한 전달 시스템 및 관련 방법 |
| EP3487416A4 (en) * | 2016-07-19 | 2020-07-29 | Avitus Orthopaedics Inc. | DEVICE FOR GENERATING A PILOT HOLE FOR ACCESS TO A SPONGIOSA |
| US10765453B2 (en) | 2017-04-18 | 2020-09-08 | Texas Scottish Rite Hospital For Children | Device and method for treating osteonecrosis |
| US10758253B2 (en) | 2017-04-18 | 2020-09-01 | Texas Scottish Rite Hospital For Children | Device and method for treating osteonecrosis |
| US20210007779A1 (en) | 2018-02-09 | 2021-01-14 | Stemmatters, Biotecnologia e Medicina Regenerativa, S.A. | Medical device for the delivery of therapeutic formulations and methods of use thereof |
| US12465370B2 (en) | 2022-11-22 | 2025-11-11 | Metal Industries Research & Development Centre | Surgical instrument |
| JP7510481B2 (ja) * | 2022-11-28 | 2024-07-03 | 財團法人金屬工業研究發展中心 | 手術器具 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5484442A (en) | 1988-10-24 | 1996-01-16 | Cook Incorporated | Intraosseous needle |
| US5601559A (en) * | 1988-10-24 | 1997-02-11 | Cook Incorporated | Intraosseous needle |
| US4969870A (en) | 1989-06-07 | 1990-11-13 | The Regents Of The University Of California | Method and apparatus for intraosseous infusions |
| ES2085441T3 (es) * | 1990-12-13 | 1996-06-01 | Cook Inc | Aguja intraosea. |
| DE4311715C2 (de) * | 1993-04-08 | 1996-02-01 | Fresenius Ag | Portkanüle |
| US6241734B1 (en) * | 1998-08-14 | 2001-06-05 | Kyphon, Inc. | Systems and methods for placing materials into bone |
| US5919196A (en) * | 1995-02-16 | 1999-07-06 | Arthrex, Inc. | Method and apparatus for osteochondral autograft transplantation |
| US6592588B1 (en) * | 1995-02-16 | 2003-07-15 | Arthrex, Inc. | Apparatus for osteochondral autograft transplantation |
| ATE339917T1 (de) | 1996-10-23 | 2006-10-15 | Oratec Interventions Inc | Vorrichtung zur behandlung von zwischenwirbelscheiben |
| US6468279B1 (en) | 1998-01-27 | 2002-10-22 | Kyphon Inc. | Slip-fit handle for hand-held instruments that access interior body regions |
| ES2228165T3 (es) | 1998-12-09 | 2005-04-01 | Cook Incorporated | Aguja hueca, curvada, superelastica, para uso medico. |
| US6210376B1 (en) * | 1999-04-08 | 2001-04-03 | New York University | Cannulated delivery pin |
| US6575919B1 (en) | 1999-10-19 | 2003-06-10 | Kyphon Inc. | Hand-held instruments that access interior body regions |
| US7081122B1 (en) * | 1999-10-19 | 2006-07-25 | Kyphon Inc. | Hand-held instruments that access interior body regions |
| KR100717224B1 (ko) * | 2000-04-05 | 2007-05-11 | 키폰 인크. | 골절되거나 병든 뼈를 치료하는 방법 및 장치 |
| JP4058614B2 (ja) * | 2001-08-09 | 2008-03-12 | 株式会社Ｊｉｍｒｏ | 骨髄針 |
| CN2527232Y (zh) * | 2002-01-04 | 2002-12-25 | 中国人民解放军第一七四医院 | 颅内血肿粉碎穿刺针 |
| CN2540161Y (zh) * | 2002-03-13 | 2003-03-19 | 徐利浩 | 体腔穿刺针及留置导管 |
| US8808284B2 (en) | 2008-09-26 | 2014-08-19 | Relievant Medsystems, Inc. | Systems for navigating an instrument through bone |
| US7699852B2 (en) * | 2003-11-19 | 2010-04-20 | Zimmer Spine, Inc. | Fenestrated bone tap and method |
| US7634823B2 (en) | 2004-03-26 | 2009-12-22 | Masco Corporation | Interface structure for a shower surround |
| US8657881B2 (en) | 2004-04-20 | 2014-02-25 | Depuy Mitek, Llc | Meniscal repair scaffold |
| WO2006076729A2 (en) * | 2005-01-14 | 2006-07-20 | Xtremi-T, Llc | Method and system for intraoperatively measuring and trimming the length of fracture fixation devices |
| EP1903961B1 (en) * | 2005-07-07 | 2012-05-16 | Crosstrees Medical, Inc. | Device for delivery of bone void filling materials |
| JP2007222472A (ja) | 2006-02-24 | 2007-09-06 | Nipro Corp | 薬剤微量投与具セット |
| CN201088612Y (zh) * | 2007-11-01 | 2008-07-23 | 杨子伟 | 多功能微创穿刺针 |
| WO2009086024A1 (en) * | 2007-12-19 | 2009-07-09 | Bassem Georgy | Device and method for orthopedic fracture fixation |
| EP2140823B1 (en) * | 2008-06-23 | 2015-08-26 | National Cancer Center | Pin assembly for operation |
| US8114112B2 (en) * | 2008-12-30 | 2012-02-14 | Cook Medical Technologies Llc | Stylet locking mechanism for medical delivery devices |
| AU2010224135A1 (en) * | 2009-03-13 | 2011-08-11 | Wyeth Llc | Bone cement delivery systems and related kits and methods |
| EP2421453A2 (en) * | 2009-04-20 | 2012-02-29 | Osteo Innovations Llc | System and method for self filling bone screws |
| CN201426765Y (zh) * | 2009-07-07 | 2010-03-24 | 张远成 | 骨端穿刺器 |
| US8574273B2 (en) * | 2009-09-09 | 2013-11-05 | Innovision, Inc. | Bone screws and methods of use thereof |
| US20110112436A1 (en) * | 2009-11-06 | 2011-05-12 | SpineSmith Partners, LP | Distraction pins for fluid aspiration |
| US8608802B2 (en) * | 2009-11-20 | 2013-12-17 | Zimmer Knee Creations, Inc. | Implantable devices for subchondral treatment of joint pain |
| CN102781370B (zh) * | 2010-03-10 | 2016-03-02 | 史密夫和内修有限公司 | 复合界面螺钉和驱动器 |
| US8758402B2 (en) * | 2010-12-17 | 2014-06-24 | Boston Scientific Scimed, Inc. | Tissue puncture closure device |
| US20120171179A1 (en) * | 2010-12-31 | 2012-07-05 | Jaewoo Pak | Apparatus, system, and method for compositions and methods for treating, preventing, or alleviating bone or cartilage diseases |
| CN103841927A (zh) * | 2011-06-09 | 2014-06-04 | 齐默尔膝部创造物公司 | 用于软骨下关节修复的器械和装置 |
| EP2765938A1 (en) * | 2011-10-13 | 2014-08-20 | KCI Licensing, Inc. | Stimulation of cartilage repair using reduced pressure treatment |
| KR20150037738A (ko) * | 2012-04-11 | 2015-04-08 | 비자이 바드 | 골-연골 간기의 자극에 의한 연골 치유, 보존 및 성장, 및 이를 위한 전달 시스템 및 관련 방법 |
-
2013
- 2013-04-11 KR KR1020147031691A patent/KR20150037738A/ko not_active Withdrawn
- 2013-04-11 AU AU2013245830A patent/AU2013245830A1/en not_active Abandoned
- 2013-04-11 HK HK15108338.7A patent/HK1207552A1/xx unknown
- 2013-04-11 CA CA2870203A patent/CA2870203A1/en not_active Abandoned
- 2013-04-11 ES ES13775734T patent/ES2772031T3/es active Active
- 2013-04-11 CN CN201380030697.0A patent/CN104661606B/zh not_active Expired - Fee Related
- 2013-04-11 WO PCT/US2013/036259 patent/WO2013155359A1/en not_active Ceased
- 2013-04-11 MX MX2014012205A patent/MX2014012205A/es unknown
- 2013-04-11 RU RU2014145346A patent/RU2014145346A/ru not_active Application Discontinuation
- 2013-04-11 US US13/861,360 patent/US9827010B2/en not_active Expired - Fee Related
- 2013-04-11 NZ NZ701804A patent/NZ701804A/en not_active IP Right Cessation
- 2013-04-11 EP EP13775734.0A patent/EP2836147B1/en active Active
- 2013-04-11 JP JP2015505925A patent/JP2015519100A/ja active Pending
-
2014
- 2014-10-19 IL IL235156A patent/IL235156A0/en unknown
- 2014-11-11 IN IN9449DEN2014 patent/IN2014DN09449A/en unknown
-
2017
- 2017-09-27 JP JP2017186176A patent/JP2018020153A/ja active Pending
- 2017-11-21 US US15/819,751 patent/US20180317962A1/en not_active Abandoned
-
2020
- 2020-04-29 US US16/862,448 patent/US11389196B2/en active Active
-
2022
- 2022-02-26 US US17/681,768 patent/US11759236B2/en active Active
-
2023
- 2023-09-18 US US18/369,325 patent/US20240000482A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20150037738A (ko) | 2015-04-08 |
| EP2836147A1 (en) | 2015-02-18 |
| US20200253637A1 (en) | 2020-08-13 |
| US20240000482A1 (en) | 2024-01-04 |
| US9827010B2 (en) | 2017-11-28 |
| RU2014145346A (ru) | 2016-06-10 |
| US20180317962A1 (en) | 2018-11-08 |
| HK1207552A1 (zh) | 2016-02-05 |
| ES2772031T3 (es) | 2020-07-07 |
| JP2015519100A (ja) | 2015-07-09 |
| US20140088551A1 (en) | 2014-03-27 |
| CN104661606B (zh) | 2018-04-06 |
| US20220280191A1 (en) | 2022-09-08 |
| EP2836147A4 (en) | 2016-04-27 |
| CA2870203A1 (en) | 2013-11-17 |
| US11389196B2 (en) | 2022-07-19 |
| EP2836147B1 (en) | 2019-12-25 |
| IN2014DN09449A (https=) | 2015-07-17 |
| MX2014012205A (es) | 2015-07-17 |
| WO2013155359A1 (en) | 2013-10-17 |
| CN104661606A (zh) | 2015-05-27 |
| JP2018020153A (ja) | 2018-02-08 |
| US11759236B2 (en) | 2023-09-19 |
| NZ701804A (en) | 2018-01-26 |
| IL235156A0 (en) | 2014-12-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11759236B2 (en) | Cartilage repair, preservation and growth by stimulation of bone-chondral interface and delivery system and methods therefor | |
| AU775688B2 (en) | Apparatus and method for fixation of osteoporotic bone | |
| US9351835B2 (en) | Method for treating joint pain and associated instruments | |
| US9339294B2 (en) | Instruments for controlled delivery of injectable materials into bone | |
| US20110125157A1 (en) | Subchondral treatment of joint pain | |
| WO2011063231A1 (en) | Subchondral treatment of joint pain | |
| US20120059380A1 (en) | Bone Cement Delivery Systems and Related Kits and Methods | |
| US9433436B2 (en) | Therapeutic material delivery system for tissue voids and cannulated implants | |
| US20130261597A1 (en) | Therapeutic Material Delivery System for Tissue Voids and Cannulated Implants | |
| JP2015519100A5 (https=) | ||
| Cunningham et al. | Arthroscopic treatment of osteochondral lesions of the talus with microfracture and platelet-rich plasma-infused micronized cartilage allograft | |
| US20150018754A1 (en) | Devices, compositions and methods for treating acute and chronic tissue damage | |
| Buskhrikidze et al. | The Hydraulic Sinus Lift Technique: Opportunities and Limitations |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |