AU2013204140B2 - Common light chain mouse - Google Patents
Common light chain mouse Download PDFInfo
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- AU2013204140B2 AU2013204140B2 AU2013204140A AU2013204140A AU2013204140B2 AU 2013204140 B2 AU2013204140 B2 AU 2013204140B2 AU 2013204140 A AU2013204140 A AU 2013204140A AU 2013204140 A AU2013204140 A AU 2013204140A AU 2013204140 B2 AU2013204140 B2 AU 2013204140B2
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| SMT201900372T1 (it) | 2010-02-08 | 2019-09-09 | Regeneron Pharma | Topo con catena leggera comune |
| US9796788B2 (en) | 2010-02-08 | 2017-10-24 | Regeneron Pharmaceuticals, Inc. | Mice expressing a limited immunoglobulin light chain repertoire |
| US20130045492A1 (en) | 2010-02-08 | 2013-02-21 | Regeneron Pharmaceuticals, Inc. | Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain |
| EP2757875B2 (en) | 2011-09-19 | 2023-03-22 | Kymab Limited | Manipulation of immunoglobulin gene diversity and multi-antibody therapeutics |
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| US9253965B2 (en) | 2012-03-28 | 2016-02-09 | Kymab Limited | Animal models and therapeutic molecules |
| KR102213535B1 (ko) | 2012-03-16 | 2021-02-08 | 리제너론 파마슈티칼스 인코포레이티드 | pH-민감성 면역글로불린 서열을 발현하는 비-사람 동물 |
| US20140013456A1 (en) | 2012-03-16 | 2014-01-09 | Regeneron Pharmaceuticals, Inc. | Histidine Engineered Light Chain Antibodies and Genetically Modified Non-Human Animals for Generating the Same |
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| US10251377B2 (en) | 2012-03-28 | 2019-04-09 | Kymab Limited | Transgenic non-human vertebrate for the expression of class-switched, fully human, antibodies |
| ES2743399T3 (es) | 2012-04-20 | 2020-02-19 | Merus Nv | Métodos y medios para la producción de moléculas heterodiméricas similares a Ig |
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| RU2016141307A (ru) | 2014-03-21 | 2018-04-24 | Регенерон Фармасьютикалз, Инк. | Отличные от человека животные, которые вырабатывают однодоменные связывающие белки |
| US11111314B2 (en) | 2015-03-19 | 2021-09-07 | Regeneron Pharmaceuticals, Inc. | Non-human animals that select for light chain variable regions that bind antigen |
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| AU2013204140A1 (en) | 2013-09-26 |
| MX353278B (es) | 2018-01-05 |
| AU2016202488C1 (en) | 2018-10-18 |
| IN2014DN08163A (enExample) | 2015-05-01 |
| CN104244709B (zh) | 2017-03-08 |
| JP2015509380A (ja) | 2015-03-30 |
| IL234207A0 (en) | 2017-04-30 |
| CN104244709A (zh) | 2014-12-24 |
| SG11201405088QA (en) | 2014-11-27 |
| EP2822379A1 (en) | 2015-01-14 |
| HK1205873A1 (en) | 2015-12-31 |
| NZ630637A (en) | 2016-09-30 |
| AU2016202488B2 (en) | 2018-04-05 |
| CN107090471A (zh) | 2017-08-25 |
| RU2683514C2 (ru) | 2019-03-28 |
| EP3165086A1 (en) | 2017-05-10 |
| MX2014010794A (es) | 2014-10-14 |
| WO2013134263A1 (en) | 2013-09-12 |
| KR20140136462A (ko) | 2014-11-28 |
| RU2014140239A (ru) | 2016-04-20 |
| CA2865029A1 (en) | 2013-09-12 |
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