AU2013202587B2 - Cell suspension and use thereof - Google Patents

Cell suspension and use thereof Download PDF

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Publication number
AU2013202587B2
AU2013202587B2 AU2013202587A AU2013202587A AU2013202587B2 AU 2013202587 B2 AU2013202587 B2 AU 2013202587B2 AU 2013202587 A AU2013202587 A AU 2013202587A AU 2013202587 A AU2013202587 A AU 2013202587A AU 2013202587 B2 AU2013202587 B2 AU 2013202587B2
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AU
Australia
Prior art keywords
cells
skin
tissue sample
epithelium
population
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AU2013202587A
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AU2013202587A1 (en
Inventor
William DOLPHIN
Andrew Quick
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Avita Medical Americas LLC
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Avita Medical Americas LLC
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Assigned to QUICK, ANDREW, DOLPHIN, William, AVITA MEDICAL PTY LTD reassignment QUICK, ANDREW Request to Amend Deed and Register Assignors: AVITA MEDICAL LTD., DOLPHIN, William, QUICK, ANDREW
Assigned to AVITA MEDICAL PTY LTD reassignment AVITA MEDICAL PTY LTD Request for Assignment Assignors: AVITA MEDICAL PTY LTD, DOLPHIN, William, QUICK, ANDREW
Assigned to AVITA Medical Americas, LLC reassignment AVITA Medical Americas, LLC Request for Assignment Assignors: AVITA MEDICAL PTY LTD
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/36—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing microorganisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3869—Epithelial tissues other than skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/73—Hydrolases (EC 3.)
    • C12N2501/734—Proteases (EC 3.4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2521/00—Culture process characterised by the use of hydrostatic pressure, flow or shear forces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2523/00—Culture process characterised by temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2527/00—Culture process characterised by the use of mechanical forces, e.g. strain, vibration

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cosmetics (AREA)
  • Prostheses (AREA)
AU2013202587A 2012-03-22 2013-03-14 Cell suspension and use thereof Active AU2013202587B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261614115P 2012-03-22 2012-03-22
US201261614112P 2012-03-22 2012-03-22
US61/614,112 2012-03-22
US61/614,115 2012-03-22
PCT/US2013/031316 WO2013142254A1 (en) 2012-03-22 2013-03-14 Cell suspension and use thereof

Publications (2)

Publication Number Publication Date
AU2013202587A1 AU2013202587A1 (en) 2013-10-10
AU2013202587B2 true AU2013202587B2 (en) 2015-08-13

Family

ID=49223227

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013202587A Active AU2013202587B2 (en) 2012-03-22 2013-03-14 Cell suspension and use thereof

Country Status (9)

Country Link
US (4) US20150079153A1 (https=)
EP (3) EP4699624A3 (https=)
CN (1) CN104685049A (https=)
AU (1) AU2013202587B2 (https=)
BR (1) BR112014023272B1 (https=)
CA (1) CA2874091C (https=)
ES (2) ES3060533T3 (https=)
HK (1) HK1207662A1 (https=)
WO (1) WO2013142254A1 (https=)

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AUPR298901A0 (en) 2001-02-07 2001-03-08 McComb Foundation, Inc., The Cell suspension preparation technique and device
DE102007040252A1 (de) 2006-09-11 2008-06-12 Gerlach, Jörg, Prof. Dr. Sprühapparat für Zellen und Methode zur Anwendung gesprühter Zellen
DE102011100450B8 (de) 2011-04-27 2013-10-17 Jörg Gerlach Apparat zum Sprühen von Zellen, Herstellung des Apparates, Methode zum Sprühen mit dem Apparat und eine Zellsuspension gesprüht mit dem Apparat
AU2013205148B2 (en) 2013-03-14 2014-10-30 AVITA Medical Americas, LLC Systems and methods for tissue processing and preparation of cell suspension therefrom
CN105250994A (zh) * 2015-10-29 2016-01-20 广州赛莱拉干细胞科技股份有限公司 一种促进皮肤伤口愈合的制剂及其制备方法和应用
JP2019517566A (ja) * 2016-06-10 2019-06-24 ライデン、ブロック 創傷パッキングを用いて創傷を治療するためのシステム及び方法
EP3468722B1 (en) 2016-06-14 2022-02-09 RenovaCare Sciences Corp. Modular device for cell spraying
CN107929817A (zh) * 2017-12-01 2018-04-20 蒋文明 一种可降解血管支架材料的制备方法
GB201913264D0 (en) * 2019-09-13 2019-10-30 Vertiacell Method and apparatus for cell isolation
EP4061923A4 (en) 2019-11-22 2024-01-03 Cutiss AG Methods and systems for producing skin grafts
US11987787B2 (en) 2020-07-22 2024-05-21 AVITA Medical Americas, LLC Devices, methods, and kits for preparing a cell suspension
CN112961820A (zh) * 2021-02-04 2021-06-15 王忠坤 一种皮肤组织采集、提取并制备细胞悬液的方法和装置
JP2024515805A (ja) * 2021-04-27 2024-04-10 アヴィータ・メディカル・インコーポレイテッド 新たに脱凝集された組織に由来する再生生物活性懸濁液および臨床治療における使用方法
JP2024517174A (ja) * 2021-04-30 2024-04-19 アヴィータ・メディカル・インコーポレイテッド 治療可能性を有する細胞懸濁液を特定するための方法およびシステムならびに関連する組成物
CN115998847B (zh) * 2022-04-15 2026-01-30 江苏瑞培生命科技有限公司 一种用于自体治疗皮肤创面的皮肤细胞分散液
US12570949B2 (en) 2022-12-27 2026-03-10 AVITA Medical Americas, LLC Systems and devices for wound therapy and related methods of use
DE202023002794U1 (de) 2022-12-27 2024-07-15 AVITA Medical Americas, LLC Kassette zur Herstellung einer regenerativen epidermalen Suspension
USD1112812S1 (en) 2023-12-22 2026-02-10 AVITA Medical Americas, LLC Tissue processing cartridge

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US20100035815A1 (en) * 2007-01-08 2010-02-11 University Of Southern California Skin wound healing compositions and methods of use thereof
US20100255052A1 (en) * 2006-06-07 2010-10-07 Manuel Eduardo Young Anze Integrated implant system (iis) biocompatible, biodegradable and bioactive, comprising a biocompatible sterile porous polymeric matrix and a gel, integrating in situ the tridimensional matrix structure

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US6660853B2 (en) 2000-12-15 2003-12-09 Al Prescott Method for purifying high molecular weight hyaluronic acid
AUPR298901A0 (en) * 2001-02-07 2001-03-08 McComb Foundation, Inc., The Cell suspension preparation technique and device
ATE510548T1 (de) 2001-02-07 2011-06-15 Mccomb Foundation Inc Zellsuspensionsherstellungstechnik und verwendung
US6649072B2 (en) * 2001-11-16 2003-11-18 Robert Brandt Method for producing autologous platelet-rich plasma
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CL2011001904A1 (es) * 2011-08-08 2012-03-09 Univ Pontificia Catolica Chile Formulacion farmaceutica que comprende celulas madres mesenquimales vivas suspendidas en un vehiculo farmaceuticamente aceptable, sistema de aplicacion topica en aerosol que las comprende; y su uso para tratar heridas.
AU2013205148B2 (en) * 2013-03-14 2014-10-30 AVITA Medical Americas, LLC Systems and methods for tissue processing and preparation of cell suspension therefrom

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US20100255052A1 (en) * 2006-06-07 2010-10-07 Manuel Eduardo Young Anze Integrated implant system (iis) biocompatible, biodegradable and bioactive, comprising a biocompatible sterile porous polymeric matrix and a gel, integrating in situ the tridimensional matrix structure
US20100035815A1 (en) * 2007-01-08 2010-02-11 University Of Southern California Skin wound healing compositions and methods of use thereof

Also Published As

Publication number Publication date
BR112014023272B1 (pt) 2022-06-07
ES2864772T3 (es) 2021-10-14
EP3896152B1 (en) 2025-12-31
CA2874091A1 (en) 2013-09-26
EP3896152A1 (en) 2021-10-20
AU2013202587A1 (en) 2013-10-10
BR112014023272A2 (https=) 2017-10-03
ES3060533T3 (en) 2026-03-26
EP2828378A1 (en) 2015-01-28
EP2828378B1 (en) 2021-02-17
EP4699624A2 (en) 2026-02-25
US20200093952A1 (en) 2020-03-26
US20220193301A1 (en) 2022-06-23
CA2874091C (en) 2023-09-26
EP4699624A3 (en) 2026-05-06
WO2013142254A1 (en) 2013-09-26
EP2828378A4 (en) 2015-11-04
US20150079153A1 (en) 2015-03-19
EP3896152C0 (en) 2025-12-31
US20200093951A1 (en) 2020-03-26
HK1207662A1 (en) 2016-02-05
CN104685049A (zh) 2015-06-03

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FGA Letters patent sealed or granted (standard patent)
HB Alteration of name in register

Owner name: DOLPHIN, W.

Free format text: FORMER NAME(S): AVITA MEDICAL LTD. ; QUICK, ANDREW; DOLPHIN, WILLIAM

Owner name: QUICK, A.

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