AU2012339616B2 - Cover member, method and treatment module for treating a biological sample on a substrate - Google Patents

Cover member, method and treatment module for treating a biological sample on a substrate Download PDF

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Publication number
AU2012339616B2
AU2012339616B2 AU2012339616A AU2012339616A AU2012339616B2 AU 2012339616 B2 AU2012339616 B2 AU 2012339616B2 AU 2012339616 A AU2012339616 A AU 2012339616A AU 2012339616 A AU2012339616 A AU 2012339616A AU 2012339616 B2 AU2012339616 B2 AU 2012339616B2
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AU
Australia
Prior art keywords
cover member
substrate
fluid
chamber
void
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2012339616A
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English (en)
Other versions
AU2012339616A1 (en
Inventor
Stephen John BAGNATO
Mark Brian Dockrill
Anthony FAVALORO
Martin LIMON
Kenneth Heng-Chong Ng
Peter Toogood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leica Biosystems Melbourne Pty Ltd
Original Assignee
Leica Biosystems Melbourne Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leica Biosystems Melbourne Pty Ltd filed Critical Leica Biosystems Melbourne Pty Ltd
Publication of AU2012339616A1 publication Critical patent/AU2012339616A1/en
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Publication of AU2012339616B2 publication Critical patent/AU2012339616B2/en
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0851—Bottom walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1861—Means for temperature control using radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1861—Means for temperature control using radiation
    • B01L2300/1866—Microwaves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/527—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU2012339616A 2011-11-16 2012-11-15 Cover member, method and treatment module for treating a biological sample on a substrate Active AU2012339616B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161560543P 2011-11-16 2011-11-16
US61/560,543 2011-11-16
PCT/AU2012/001407 WO2013071352A1 (en) 2011-11-16 2012-11-15 Cover member, method and treatment module for treating a biological sample on a substrate

Publications (2)

Publication Number Publication Date
AU2012339616A1 AU2012339616A1 (en) 2014-06-12
AU2012339616B2 true AU2012339616B2 (en) 2016-04-28

Family

ID=48428835

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2012339616A Active AU2012339616B2 (en) 2011-11-16 2012-11-15 Cover member, method and treatment module for treating a biological sample on a substrate

Country Status (9)

Country Link
US (3) US10549271B2 (enExample)
EP (1) EP2780721B1 (enExample)
JP (2) JP2014533823A (enExample)
CN (1) CN104094122B (enExample)
AU (1) AU2012339616B2 (enExample)
BR (1) BR112014011935B1 (enExample)
CA (1) CA2855511C (enExample)
IN (1) IN2014CN04294A (enExample)
WO (1) WO2013071352A1 (enExample)

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WO2011053631A1 (en) 2009-10-28 2011-05-05 Alentic Microscience Inc. Microscopy imaging
CN110243653A (zh) * 2012-11-01 2019-09-17 莱卡生物系统墨尔本私人有限公司 流体输送系统
EP2914949B1 (en) * 2012-11-01 2022-12-21 Leica Biosystems Melbourne Pty Ltd Slide staining assembly and cover member
US9518920B2 (en) 2013-06-26 2016-12-13 Alentic Microscience Inc. Sample processing improvements for microscopy
US10502666B2 (en) 2013-02-06 2019-12-10 Alentic Microscience Inc. Sample processing improvements for quantitative microscopy
ES2885681T3 (es) * 2013-10-04 2021-12-15 Biogenex Laboratories Inc Conjunto para formar una microcámara para un sustrato invertido
US10137450B2 (en) * 2014-07-18 2018-11-27 Tecan Trading Ag Microfluidics cartridge with pipetting guide
CN107615039A (zh) * 2015-05-26 2018-01-19 奥林巴斯株式会社 检查体染色装置和检查体染色方法
US9958362B1 (en) * 2015-10-02 2018-05-01 The Florida State University Research Foundation, Inc. Microscope sample preparation device
EP3427035B1 (en) * 2016-07-26 2023-08-30 Hewlett-Packard Development Company, L.P. Microfluidic apparatuses
GB2562081B (en) 2017-05-04 2020-07-15 Imrali Ahmet Slide cleaner
EP3441143B1 (en) * 2017-08-08 2022-04-13 Roche Diagnostics GmbH Laboratory instrument base plate
CN108152109B (zh) * 2017-12-14 2021-02-09 深圳达盟生物科技有限公司 载玻片盖体及其用于组织切片清洗的方法
CN108387428A (zh) * 2018-02-26 2018-08-10 深圳安诺康生物医疗有限公司 一种病理切片的染色方法
AU2019302550B2 (en) 2018-07-10 2024-05-23 Nanocytomics, LLC Automated sample deposition and staining systems and associated methods
KR102246609B1 (ko) * 2018-08-01 2021-04-30 주식회사 미코바이오메드 복수의 열 블록을 구비한 핵산 증폭 장치
AU2019404614B2 (en) * 2018-12-20 2024-08-01 Leica Biosystems Melbourne Pty Ltd Bulk fluid wash module
KR102833793B1 (ko) * 2018-12-20 2025-07-16 라이카 바이오시스템즈 멜버른 피티와이 엘티디 슬라이드 출력 모듈
US12220699B2 (en) * 2019-01-21 2025-02-11 Forward Biotech, Inc. Liquid evaluation
CN109900542A (zh) * 2019-03-15 2019-06-18 深圳市金准生物医学工程有限公司 测试卡温育的自动封闭的腔体装置
EP4542195A3 (en) * 2019-05-14 2025-07-09 Ventana Medical Systems, Inc. Assembly and system including a biological sample treatment chamber
EP3825004A1 (en) * 2019-11-22 2021-05-26 Koninklijke Philips N.V. New multi-functional fluidic device for clamping biopsies
WO2021215755A1 (ko) * 2020-04-24 2021-10-28 (주)바이오니아 추적이 가능한 멀티웰플레이트용 정밀시료주입장치
US12699106B2 (en) 2021-03-31 2026-08-04 Asp Health Inc. Benchtop instrument and consumables for sample deposition and staining
CN115773920B (zh) * 2021-09-06 2024-04-19 南京泰立瑞信息科技有限公司 一种低损耗、自动化的切片样本染色方法和系统
US12692469B2 (en) 2021-10-07 2026-07-28 Coopersurgical, Inc. Modular incubators for configurable workstations
EP4453532A4 (en) * 2021-12-23 2025-12-17 Leica Biosystems Melbourne Pty SAMPLE PROCESSING INSTRUCTIONS FOR TREATMENT OF A SAMPLE ON A SUBSTRATE
HU231596B1 (hu) * 2022-02-04 2025-03-28 3Dhistech Kft. Tárgylemez takaró eszköz, valamint inkubációs kamra, amely ilyen tárgylemez takaró eszközt tartalmaz
US20240167921A1 (en) * 2022-11-18 2024-05-23 Zomedica Inc. Methods and systems for slide treatment processing
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CN118874564B (zh) * 2024-07-10 2025-07-15 杭州跃真生物科技有限公司 一种样本反应容置装置及方法

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Also Published As

Publication number Publication date
US20230077728A1 (en) 2023-03-16
JP2018021932A (ja) 2018-02-08
IN2014CN04294A (enExample) 2015-09-04
WO2013071352A1 (en) 2013-05-23
JP6633586B2 (ja) 2020-01-22
BR112014011935B1 (pt) 2020-11-03
US12157118B2 (en) 2024-12-03
EP2780721A4 (en) 2015-07-01
CA2855511C (en) 2021-03-09
US11420200B2 (en) 2022-08-23
EP2780721A1 (en) 2014-09-24
AU2012339616A1 (en) 2014-06-12
EP2780721B1 (en) 2017-08-16
BR112014011935A2 (pt) 2017-05-30
JP2014533823A (ja) 2014-12-15
US20140315256A1 (en) 2014-10-23
US10549271B2 (en) 2020-02-04
CN104094122B (zh) 2017-03-22
CA2855511A1 (en) 2013-05-23
US20200188904A1 (en) 2020-06-18
CN104094122A (zh) 2014-10-08

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