AU2012334066A1 - Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an N-containing group as vanilloid receptor ligands - Google Patents

Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an N-containing group as vanilloid receptor ligands Download PDF

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Publication number
AU2012334066A1
AU2012334066A1 AU2012334066A AU2012334066A AU2012334066A1 AU 2012334066 A1 AU2012334066 A1 AU 2012334066A1 AU 2012334066 A AU2012334066 A AU 2012334066A AU 2012334066 A AU2012334066 A AU 2012334066A AU 2012334066 A1 AU2012334066 A1 AU 2012334066A1
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AU
Australia
Prior art keywords
methyl
phenyl
pyrazol
butyl
tert
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2012334066A
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English (en)
Inventor
Gregor Bahrenberg
Thomas Christoph
Nils Damann
Robert Frank-Foltyn
Myeong-Seop Kim
Yong-Soo Kim
Jeewoo Lee
Bernhard Lesch
Derek John Saunders
Hannelore Stockhausen
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Gruenenthal GmbH
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Gruenenthal GmbH
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Filing date
Publication date
Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH
Publication of AU2012334066A1 publication Critical patent/AU2012334066A1/en
Abandoned legal-status Critical Current

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/04—Anorexiants; Antiobesity agents
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61P9/00—Drugs for disorders of the cardiovascular system
AU2012334066A 2011-11-09 2012-11-08 Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an N-containing group as vanilloid receptor ligands Abandoned AU2012334066A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11008913 2011-11-09
EP11008913.3 2011-11-09
PCT/EP2012/072141 WO2013068462A1 (en) 2011-11-09 2012-11-08 Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an n-containing group as vanilloid receptor ligands

Publications (1)

Publication Number Publication Date
AU2012334066A1 true AU2012334066A1 (en) 2014-05-22

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ID=47143123

Family Applications (1)

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AU2012334066A Abandoned AU2012334066A1 (en) 2011-11-09 2012-11-08 Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an N-containing group as vanilloid receptor ligands

Country Status (13)

Country Link
EP (1) EP2776399A1 (ja)
JP (1) JP2014532742A (ja)
KR (1) KR20140096351A (ja)
CN (1) CN103906736A (ja)
AR (1) AR088701A1 (ja)
AU (1) AU2012334066A1 (ja)
BR (1) BR112014010957A2 (ja)
CA (1) CA2854935A1 (ja)
HK (1) HK1202116A1 (ja)
IN (1) IN2014KN00847A (ja)
MX (1) MX2014005611A (ja)
TW (1) TW201326134A (ja)
WO (1) WO2013068462A1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101909092B1 (ko) 2014-11-24 2018-10-17 (주) 메디프론디비티 바닐로이드 수용체 리간드 ii로서의 치환된 옥사졸계 및 싸이아졸계 카복스아미드 및 우레아 유도체
CN114920697A (zh) * 2022-05-16 2022-08-19 河南应用技术职业学院 杂环基取代的茚满丙酰胺类化合物及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1020447A4 (en) * 1997-09-11 2000-11-15 Nissan Chemical Ind Ltd PYRAZOLE-BASED COMPOUNDS AND PLANT DISEASE CONTROL AGENT
AU2006303437B2 (en) * 2005-10-19 2012-06-28 Grunenthal Gmbh Novel vanilloid receptor ligands and their use for producing medicaments
CN101679297B (zh) * 2006-12-08 2012-01-11 埃克塞利希斯股份有限公司 Lxr和fxr调节剂
BRPI0810035A2 (pt) * 2007-04-16 2016-07-26 Gruenenthal Gmbh ligantes de receptor de vaniloide e seu uso para produção de medicamento
DE102007018151A1 (de) * 2007-04-16 2008-10-23 Günenthal GmbH Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln
SI2427436T1 (sl) * 2009-05-07 2013-04-30 Grunenthal Gmbh Substituirani aromatski karboksamidni in sečninski derivati kot ligandi vaniloidnega receptorja
AR076752A1 (es) 2009-05-07 2011-07-06 Gruenenthal Chemie Fenilureas y fenilamidas sustituidas como ligandos del receptor de vanilloides.
WO2013068463A1 (en) * 2011-11-09 2013-05-16 Grünenthal GmbH Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an n-cyclic group as vanilloid receptor ligands

Also Published As

Publication number Publication date
TW201326134A (zh) 2013-07-01
AR088701A1 (es) 2014-06-25
CN103906736A (zh) 2014-07-02
KR20140096351A (ko) 2014-08-05
IN2014KN00847A (ja) 2015-10-02
WO2013068462A1 (en) 2013-05-16
HK1202116A1 (en) 2015-09-18
JP2014532742A (ja) 2014-12-08
EP2776399A1 (en) 2014-09-17
MX2014005611A (es) 2014-07-30
BR112014010957A2 (pt) 2017-06-06
CA2854935A1 (en) 2013-05-16

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MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted