AU2012225548B2 - Methods and compositions for treating depression using cyclobenzaprine - Google Patents

Methods and compositions for treating depression using cyclobenzaprine Download PDF

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Publication number
AU2012225548B2
AU2012225548B2 AU2012225548A AU2012225548A AU2012225548B2 AU 2012225548 B2 AU2012225548 B2 AU 2012225548B2 AU 2012225548 A AU2012225548 A AU 2012225548A AU 2012225548 A AU2012225548 A AU 2012225548A AU 2012225548 B2 AU2012225548 B2 AU 2012225548B2
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cyclobenzaprine
day
dose
depression
administered
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AU2012225548A1 (en
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Seth Lederman
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Tonix Pharma Holdings Ltd
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Tonix Pharma Holdings Ltd
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Publication of AU2012225548A1 publication Critical patent/AU2012225548A1/en
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Priority to AU2016222412A priority Critical patent/AU2016222412B2/en
Priority to AU2018204633A priority patent/AU2018204633C1/en
Assigned to TONIX PHARMA HOLDINGS LIMITED reassignment TONIX PHARMA HOLDINGS LIMITED Request for Assignment Assignors: Tonix Pharmaceuticals, Inc.
Priority to AU2020203874A priority patent/AU2020203874B2/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2012225548A 2011-03-07 2012-03-06 Methods and compositions for treating depression using cyclobenzaprine Active AU2012225548B2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2016222412A AU2016222412B2 (en) 2011-03-07 2016-08-31 Methods and Compositions for Treating Depression Using Cyclobenzaprine
AU2018204633A AU2018204633C1 (en) 2011-03-07 2018-06-26 Methods and Compositions for Treating Depression Using Cyclobenzaprine
AU2020203874A AU2020203874B2 (en) 2011-03-07 2020-06-11 Methods and compositions for treating depression using cyclobenzaprine

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161449838P 2011-03-07 2011-03-07
US61/449,838 2011-03-07
PCT/US2012/027926 WO2012122193A1 (en) 2011-03-07 2012-03-06 Methods and compositions for treating depression using cyclobenzaprine

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2016222412A Division AU2016222412B2 (en) 2011-03-07 2016-08-31 Methods and Compositions for Treating Depression Using Cyclobenzaprine

Publications (2)

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AU2012225548A1 AU2012225548A1 (en) 2013-09-19
AU2012225548B2 true AU2012225548B2 (en) 2016-06-02

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ID=46796107

Family Applications (4)

Application Number Title Priority Date Filing Date
AU2012225548A Active AU2012225548B2 (en) 2011-03-07 2012-03-06 Methods and compositions for treating depression using cyclobenzaprine
AU2016222412A Active AU2016222412B2 (en) 2011-03-07 2016-08-31 Methods and Compositions for Treating Depression Using Cyclobenzaprine
AU2018204633A Active AU2018204633C1 (en) 2011-03-07 2018-06-26 Methods and Compositions for Treating Depression Using Cyclobenzaprine
AU2020203874A Active AU2020203874B2 (en) 2011-03-07 2020-06-11 Methods and compositions for treating depression using cyclobenzaprine

Family Applications After (3)

Application Number Title Priority Date Filing Date
AU2016222412A Active AU2016222412B2 (en) 2011-03-07 2016-08-31 Methods and Compositions for Treating Depression Using Cyclobenzaprine
AU2018204633A Active AU2018204633C1 (en) 2011-03-07 2018-06-26 Methods and Compositions for Treating Depression Using Cyclobenzaprine
AU2020203874A Active AU2020203874B2 (en) 2011-03-07 2020-06-11 Methods and compositions for treating depression using cyclobenzaprine

Country Status (18)

Country Link
US (1) US11998516B2 (cg-RX-API-DMAC7.html)
EP (2) EP3682885A1 (cg-RX-API-DMAC7.html)
JP (2) JP2014507475A (cg-RX-API-DMAC7.html)
AU (4) AU2012225548B2 (cg-RX-API-DMAC7.html)
CA (1) CA2829200C (cg-RX-API-DMAC7.html)
CY (1) CY1122998T1 (cg-RX-API-DMAC7.html)
DK (1) DK2683245T4 (cg-RX-API-DMAC7.html)
ES (1) ES2773834T5 (cg-RX-API-DMAC7.html)
FI (1) FI2683245T4 (cg-RX-API-DMAC7.html)
HR (1) HRP20200142T4 (cg-RX-API-DMAC7.html)
HU (1) HUE048596T2 (cg-RX-API-DMAC7.html)
LT (1) LT2683245T (cg-RX-API-DMAC7.html)
PL (1) PL2683245T5 (cg-RX-API-DMAC7.html)
PT (1) PT2683245T (cg-RX-API-DMAC7.html)
RS (1) RS60240B2 (cg-RX-API-DMAC7.html)
SI (1) SI2683245T2 (cg-RX-API-DMAC7.html)
SM (1) SMT202000083T1 (cg-RX-API-DMAC7.html)
WO (1) WO2012122193A1 (cg-RX-API-DMAC7.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SMT201700578T1 (it) * 2009-11-20 2018-01-11 Tonix Pharma Holdings Ltd Metodo e composizioni per trattare i sintomi associati al disturbo da stress post-traumatico usando ciclobenzaprina
US20110319389A1 (en) 2010-06-24 2011-12-29 Tonix Pharmaceuticals, Inc. Methods and compositions for treating fatigue associated with disordered sleep using very low dose cyclobenzaprine
US11998516B2 (en) 2011-03-07 2024-06-04 Tonix Pharma Holdings Limited Methods and compositions for treating depression using cyclobenzaprine
SG10201707528WA (en) 2013-03-15 2017-10-30 Tonix Pharmaceuticals Inc Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride
WO2015150948A1 (en) * 2014-03-29 2015-10-08 Wockhardt Limited Modified release solid oral pharmaceutical compositions of cyclobenzaprine or a salt thereof
MY186047A (en) 2014-09-18 2021-06-17 Tonix Pharma Holdings Ltd Eutectic formulations of cyclobenzaprine hydrochloride
CN106890129A (zh) * 2015-12-18 2017-06-27 健乔信元医药生技股份有限公司 环苄普林之延释剂型
SG11202004799TA (en) * 2017-12-11 2020-06-29 Tonix Pharma Holdings Ltd Cyclobenzaprine treatment for agitation, psychosis and cognitive decline in dementia and neurodegenerative conditions

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Also Published As

Publication number Publication date
PT2683245T (pt) 2020-02-21
SMT202000083T1 (it) 2020-05-08
LT2683245T (lt) 2020-03-25
EP2683245A1 (en) 2014-01-15
RS60240B2 (sr) 2023-05-31
JP2016053095A (ja) 2016-04-14
US20120232159A1 (en) 2012-09-13
RS60240B1 (sr) 2020-06-30
AU2016222412B2 (en) 2018-03-29
EP2683245B2 (en) 2022-12-07
DK2683245T4 (da) 2023-01-09
AU2020203874A1 (en) 2020-07-02
SI2683245T1 (sl) 2020-07-31
EP3682885A1 (en) 2020-07-22
US11998516B2 (en) 2024-06-04
AU2018204633B2 (en) 2020-03-12
AU2018204633A1 (en) 2018-07-12
AU2016222412A1 (en) 2016-09-22
HRP20200142T4 (hr) 2023-02-17
PL2683245T5 (pl) 2023-03-20
WO2012122193A1 (en) 2012-09-13
NZ614725A (en) 2016-07-29
FI2683245T4 (fi) 2023-01-13
DK2683245T3 (da) 2020-02-24
ES2773834T3 (es) 2020-07-15
HUE048596T2 (hu) 2020-08-28
AU2012225548A1 (en) 2013-09-19
PL2683245T3 (pl) 2020-10-05
AU2018204633C1 (en) 2020-09-10
AU2020203874B2 (en) 2021-09-09
CA2829200C (en) 2022-05-03
ES2773834T5 (es) 2023-03-16
EP2683245B1 (en) 2019-12-25
CA2829200A1 (en) 2012-09-13
CY1122998T1 (el) 2021-10-29
JP2014507475A (ja) 2014-03-27
NZ714294A (en) 2017-06-30
EP2683245A4 (en) 2014-08-27
SI2683245T2 (sl) 2023-04-28
HRP20200142T1 (hr) 2020-06-26

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