AU2011333427A1 - 4- (5-cyano-pyrazol-1-yl) -piperidine derivatives as GPR 119 modulators - Google Patents
4- (5-cyano-pyrazol-1-yl) -piperidine derivatives as GPR 119 modulators Download PDFInfo
- Publication number
- AU2011333427A1 AU2011333427A1 AU2011333427A AU2011333427A AU2011333427A1 AU 2011333427 A1 AU2011333427 A1 AU 2011333427A1 AU 2011333427 A AU2011333427 A AU 2011333427A AU 2011333427 A AU2011333427 A AU 2011333427A AU 2011333427 A1 AU2011333427 A1 AU 2011333427A1
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- Australia
- Prior art keywords
- methyl
- carboxylate
- cyano
- pyrazol
- piperidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- DNUTZBZXLPWRJG-UHFFFAOYSA-M piperidine-1-carboxylate Chemical compound [O-]C(=O)N1CCCCC1 DNUTZBZXLPWRJG-UHFFFAOYSA-M 0.000 claims description 94
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Classifications
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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Landscapes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US41644110P | 2010-11-23 | 2010-11-23 | |
| US61/416,441 | 2010-11-23 | ||
| PCT/IB2011/054996 WO2012069948A1 (en) | 2010-11-23 | 2011-11-09 | 4- (5-cyano-pyrazol-1-yl) -piperidine derivatives as gpr 119 modulators |
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| AU2011333427A1 true AU2011333427A1 (en) | 2013-04-11 |
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| JP (1) | JP2013543885A (es) |
| KR (1) | KR20130083915A (es) |
| CN (1) | CN103298801A (es) |
| AP (1) | AP2013006809A0 (es) |
| AR (1) | AR088121A1 (es) |
| AU (1) | AU2011333427A1 (es) |
| BR (1) | BR112013011865A2 (es) |
| CA (1) | CA2814231A1 (es) |
| CL (1) | CL2013001054A1 (es) |
| CO (1) | CO6801716A2 (es) |
| CR (1) | CR20130139A (es) |
| CU (1) | CU20130059A7 (es) |
| DO (1) | DOP2013000102A (es) |
| EA (1) | EA201370118A1 (es) |
| EC (1) | ECSP13012630A (es) |
| GT (1) | GT201300135A (es) |
| MA (1) | MA34805B1 (es) |
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| UY (1) | UY33742A (es) |
| WO (1) | WO2012069948A1 (es) |
| ZA (1) | ZA201302362B (es) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014011926A1 (en) | 2012-07-11 | 2014-01-16 | Elcelyx Therapeutics, Inc. | Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk |
| WO2012170867A1 (en) | 2011-06-09 | 2012-12-13 | Rhizen Pharmaceuticals Sa | Novel compounds as modulators of gpr-119 |
| JP2017119628A (ja) * | 2014-05-09 | 2017-07-06 | 日産化学工業株式会社 | 置換アゾール化合物及び糖尿病治療薬 |
| CN104892517A (zh) * | 2015-02-13 | 2015-09-09 | 佛山市赛维斯医药科技有限公司 | 酰肼类化合物、其制备方法及用途 |
| CN104592120A (zh) * | 2015-02-13 | 2015-05-06 | 佛山市赛维斯医药科技有限公司 | 一种环丙基酰肼和甲氧苯类gpr119激动剂、制备方法及其用途 |
| CN104610151A (zh) * | 2015-02-13 | 2015-05-13 | 佛山市赛维斯医药科技有限公司 | 含酰肼和烷氧苯类结构的化合物、其制备方法及用途 |
| EP3416959B1 (en) | 2016-02-18 | 2021-05-12 | Syngenta Participations AG | Pesticidally active pyrazole derivatives |
| CN106631992B (zh) * | 2017-01-05 | 2019-01-18 | 桑迪亚医药技术（上海）有限责任公司 | 一种4-氧-3,4-二氢-2h-吡啶-1-甲酸叔丁酯的合成方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2009014910A2 (en) * | 2007-07-19 | 2009-01-29 | Metabolex, Inc. | N-azacyclic substituted pyrrole, pyrazole, imidazole, triazole and tetrazole derivatives as agonists of the rup3 or gpr119 receptor for the treatment of diabetes and metabolic disorders |
| EP2280704B1 (en) * | 2008-03-31 | 2015-05-13 | Cymabay Therapeutics, Inc. | Oxymethylene aryl compounds and uses thereof |
| BRPI1014636A2 (pt) * | 2009-06-05 | 2016-04-05 | Pfizer | moduladores de gpr 119 |
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2011
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- 2011-11-09 JP JP2013540458A patent/JP2013543885A/ja active Pending
- 2011-11-09 KR KR1020137013064A patent/KR20130083915A/ko not_active Application Discontinuation
- 2011-11-09 AU AU2011333427A patent/AU2011333427A1/en not_active Abandoned
- 2011-11-09 MA MA35928A patent/MA34805B1/fr unknown
- 2011-11-09 CN CN2011800550665A patent/CN103298801A/zh active Pending
- 2011-11-09 SG SG2013023189A patent/SG189830A1/en unknown
- 2011-11-09 PE PE2013001058A patent/PE20140409A1/es not_active Application Discontinuation
- 2011-11-09 WO PCT/IB2011/054996 patent/WO2012069948A1/en active Application Filing
- 2011-11-09 CA CA2814231A patent/CA2814231A1/en not_active Abandoned
- 2011-11-09 BR BR112013011865A patent/BR112013011865A2/pt not_active IP Right Cessation
- 2011-11-09 EA EA201370118A patent/EA201370118A1/ru unknown
- 2011-11-09 MX MX2013004083A patent/MX2013004083A/es unknown
- 2011-11-09 AP AP2013006809A patent/AP2013006809A0/xx unknown
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- 2011-11-22 AR ARP110104351A patent/AR088121A1/es not_active Application Discontinuation
- 2011-11-22 TW TW100142804A patent/TWI433843B/zh not_active IP Right Cessation
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2013
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- 2013-04-16 CL CL2013001054A patent/CL2013001054A1/es unknown
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- 2013-05-13 NI NI201300044A patent/NI201300044A/es unknown
- 2013-05-20 EC ECSP13012630 patent/ECSP13012630A/es unknown
- 2013-05-21 GT GT201300135A patent/GT201300135A/es unknown
- 2013-05-23 CO CO13127143A patent/CO6801716A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201302362B (en) | 2014-06-25 |
| KR20130083915A (ko) | 2013-07-23 |
| UY33742A (es) | 2012-06-29 |
| TW201300373A (zh) | 2013-01-01 |
| TWI433843B (zh) | 2014-04-11 |
| CA2814231A1 (en) | 2012-05-31 |
| CU20130059A7 (es) | 2013-06-28 |
| MA34805B1 (fr) | 2014-01-02 |
| DOP2013000102A (es) | 2013-07-15 |
| AR088121A1 (es) | 2014-05-14 |
| ECSP13012630A (es) | 2013-07-31 |
| WO2012069948A1 (en) | 2012-05-31 |
| CO6801716A2 (es) | 2013-11-29 |
| AP2013006809A0 (en) | 2013-04-30 |
| CN103298801A (zh) | 2013-09-11 |
| BR112013011865A2 (pt) | 2016-08-23 |
| CR20130139A (es) | 2013-06-28 |
| PE20140409A1 (es) | 2014-03-23 |
| NI201300044A (es) | 2013-08-01 |
| EP2643310A1 (en) | 2013-10-02 |
| MX2013004083A (es) | 2013-06-13 |
| JP2013543885A (ja) | 2013-12-09 |
| CL2013001054A1 (es) | 2013-09-27 |
| EA201370118A1 (ru) | 2013-12-30 |
| SG189830A1 (en) | 2013-06-28 |
| GT201300135A (es) | 2015-02-19 |
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| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |