AU2010286511B2 - SDF-1 delivery for treating ischemic tissue - Google Patents
SDF-1 delivery for treating ischemic tissue Download PDFInfo
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- AU2010286511B2 AU2010286511B2 AU2010286511A AU2010286511A AU2010286511B2 AU 2010286511 B2 AU2010286511 B2 AU 2010286511B2 AU 2010286511 A AU2010286511 A AU 2010286511A AU 2010286511 A AU2010286511 A AU 2010286511A AU 2010286511 B2 AU2010286511 B2 AU 2010286511B2
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
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- Veterinary Medicine (AREA)
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- Engineering & Computer Science (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| US23777509P | 2009-08-28 | 2009-08-28 | |
| US61/237,775 | 2009-08-28 | ||
| US33421610P | 2010-05-13 | 2010-05-13 | |
| US61/334,216 | 2010-05-13 | ||
| PCT/US2010/047175 WO2011026041A2 (en) | 2009-08-28 | 2010-08-30 | Sdf-1 delivery for treating ischemic tissue |
Publications (2)
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| AU2010286511A1 AU2010286511A1 (en) | 2012-04-12 |
| AU2010286511B2 true AU2010286511B2 (en) | 2016-05-26 |
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| AU2010286511A Ceased AU2010286511B2 (en) | 2009-08-28 | 2010-08-30 | SDF-1 delivery for treating ischemic tissue |
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| CN (1) | CN102740894B (https=) |
| AU (1) | AU2010286511B2 (https=) |
| BR (1) | BR112012004395B8 (https=) |
| CA (1) | CA2772610C (https=) |
| MX (1) | MX357779B (https=) |
| WO (1) | WO2011026041A2 (https=) |
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| US20050271639A1 (en) * | 2002-08-22 | 2005-12-08 | Penn Marc S | Genetically engineered cells for therapeutic applications |
| WO2008121719A1 (en) | 2007-03-30 | 2008-10-09 | The Cleveland Clinic Foundation | Method of treating ischemic disorders |
| CA2709398C (en) | 2007-12-14 | 2017-11-07 | The Cleveland Clinic Foundation | Use of stromal cell-derived factor 1 for promoting wound healing |
| WO2011026041A2 (en) | 2009-08-28 | 2011-03-03 | The Cleveland Clinic Foundation | Sdf-1 delivery for treating ischemic tissue |
| WO2011106234A1 (en) | 2010-02-25 | 2011-09-01 | Provasculon, Inc. | Protease-resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
| WO2012051515A2 (en) * | 2010-10-14 | 2012-04-19 | University Of Central Florida Research Foundation, Inc. | Cardiac induced pluripotent stem cells and methods of use in repair and regeneration of myocardium |
| US20130136729A1 (en) * | 2011-11-11 | 2013-05-30 | University of Virginia Patent Foundation, d/b/a University of Virginia Licensing & Ventures Group | Compositions and methods for targeting and treating diseases and injuries using adeno-associated virus vectors |
| EA031883B1 (ru) * | 2013-03-15 | 2019-03-29 | Джувентас Терапьютикс, Инк. | Способ ингибирования и/или снижения образования рубцовой ткани |
| KR20160005021A (ko) * | 2013-03-15 | 2016-01-13 | 더 클리브랜드 클리닉 파운데이션 | 허혈 조직 처리를 위한 sdf-1의 전달 |
| EP2968608A4 (en) * | 2013-03-15 | 2016-10-26 | Cleveland Clinic Foundation | RETROGRADE ADMINISTRATION OF SDF-1 FOR THE TREATMENT OF MYOCARDIAL INFARCTION |
| US10166044B1 (en) | 2013-05-31 | 2019-01-01 | Freshwater Bay Industries, Llc | Apparatus for repositioning the vagina, cervix, uterus and pelvic floor and method to secure same |
| US20160278810A1 (en) | 2013-05-31 | 2016-09-29 | Mark Edmund Richey | Vaginal surgical apparatus |
| WO2015168145A1 (en) * | 2014-04-28 | 2015-11-05 | Penn Marc S | Sdf-1 delivery for treating advanced ischemic cardiomyopathy |
| US10420818B2 (en) | 2014-05-08 | 2019-09-24 | Wake Forest University Health Sciences | Methods of treating incontinence and other sphincter deficiency disorders |
| US10696974B2 (en) | 2014-12-23 | 2020-06-30 | Ilya Pharma Ab | Methods for wound healing |
| SG11201803934YA (en) | 2015-11-11 | 2018-06-28 | Intrexon Corp | Compositions and methods for expression of multiple biologically active polypeptides from a single vector for treatment of cardiac conditions and other pathologies |
| WO2018183625A1 (en) * | 2017-03-30 | 2018-10-04 | Wake Forest University Health Sciences | Methods of treatment for kidney disease |
| US11583571B2 (en) | 2017-05-13 | 2023-02-21 | The Johns Hopkins University | Stromal derived factor 1 and its use in the prevention and treatment of erectile dysfunction |
| US11654181B2 (en) | 2017-08-11 | 2023-05-23 | Wake Forest University Health Sciences | Use of CXCL12 for therapy after prostate surgery |
| EP3781182A4 (en) * | 2018-04-18 | 2021-11-17 | Summa Health | COMPOSITIONS AND METHODS OF TREATMENT OF ISCHEMIA AND CARDIOMYOPATHIA |
| GB2631601A (en) * | 2022-02-04 | 2025-01-08 | Elixirgen Llc | Cell therapy protocol systems and methods |
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- 2010-08-30 CA CA2772610A patent/CA2772610C/en not_active Expired - Fee Related
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- 2010-08-30 JP JP2012527071A patent/JP5856059B2/ja active Active
- 2010-08-30 CN CN201080043895.7A patent/CN102740894B/zh active Active
- 2010-08-30 EP EP10812718.4A patent/EP2473196B1/en not_active Not-in-force
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Also Published As
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| US9844581B2 (en) | 2017-12-19 |
| US20130303597A1 (en) | 2013-11-14 |
| CA2772610C (en) | 2018-01-23 |
| JP5856059B2 (ja) | 2016-02-09 |
| BR112012004395A2 (pt) | 2016-11-16 |
| US8513213B2 (en) | 2013-08-20 |
| EP2473196A4 (en) | 2015-01-07 |
| WO2011026041A9 (en) | 2011-07-21 |
| MX357779B (es) | 2018-07-24 |
| CA2772610A1 (en) | 2011-03-03 |
| MX2012002610A (es) | 2012-08-23 |
| US8883756B2 (en) | 2014-11-11 |
| CN102740894A (zh) | 2012-10-17 |
| CN102740894B (zh) | 2015-07-15 |
| US8513007B2 (en) | 2013-08-20 |
| EP2473196B1 (en) | 2017-05-31 |
| JP2013503202A (ja) | 2013-01-31 |
| US20120283315A1 (en) | 2012-11-08 |
| US20140135383A1 (en) | 2014-05-15 |
| BR112012004395B8 (pt) | 2021-05-25 |
| US20120289586A1 (en) | 2012-11-15 |
| EP2473196A2 (en) | 2012-07-11 |
| WO2011026041A2 (en) | 2011-03-03 |
| US20120289585A1 (en) | 2012-11-15 |
| AU2010286511A1 (en) | 2012-04-12 |
| BR112012004395B1 (pt) | 2021-01-12 |
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