AU2010258716B2 - Compositions and methods for dehydrated storage of on-board reagents in microfluidic devices - Google Patents
Compositions and methods for dehydrated storage of on-board reagents in microfluidic devices Download PDFInfo
- Publication number
- AU2010258716B2 AU2010258716B2 AU2010258716A AU2010258716A AU2010258716B2 AU 2010258716 B2 AU2010258716 B2 AU 2010258716B2 AU 2010258716 A AU2010258716 A AU 2010258716A AU 2010258716 A AU2010258716 A AU 2010258716A AU 2010258716 B2 AU2010258716 B2 AU 2010258716B2
- Authority
- AU
- Australia
- Prior art keywords
- spot
- microfluidic
- reagent
- gel
- microfluidic cartridge
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Manufacture Of Macromolecular Shaped Articles (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18644209P | 2009-06-12 | 2009-06-12 | |
| US61/186,442 | 2009-06-12 | ||
| PCT/US2010/038141 WO2010144683A2 (en) | 2009-06-12 | 2010-06-10 | Compositions and methods for dehydrated storage of on-board reagents in microfluidic devices |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2010258716A1 AU2010258716A1 (en) | 2012-01-12 |
| AU2010258716B2 true AU2010258716B2 (en) | 2015-11-12 |
Family
ID=42734808
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2010258716A Active AU2010258716B2 (en) | 2009-06-12 | 2010-06-10 | Compositions and methods for dehydrated storage of on-board reagents in microfluidic devices |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8921085B2 (https=) |
| EP (1) | EP2440672B1 (https=) |
| JP (2) | JP5953229B2 (https=) |
| CN (1) | CN102803507B (https=) |
| AU (1) | AU2010258716B2 (https=) |
| WO (1) | WO2010144683A2 (https=) |
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| JP5953229B2 (ja) | 2009-06-12 | 2016-07-20 | マイクロニクス, インコーポレイテッド | マイクロ流体デバイス内でオンボード試薬を脱水保存する組成物および方法 |
| EP2528687B1 (en) | 2010-01-29 | 2018-08-22 | Micronics, Inc. | System comprising a host instrument and a microfluidic cartridge for assays |
| EP2548022B1 (en) * | 2010-03-18 | 2016-03-16 | The Regents Of The University Of Michigan | Multiphase microarrays and uses thereof |
| EP2582850B1 (en) * | 2010-06-21 | 2016-11-09 | Life Technologies Corporation | Compositions, kits, and methods for synthesis and/or detection of nucleic acids |
| US9731297B2 (en) * | 2011-01-06 | 2017-08-15 | Meso Scale Technologies, Llc. | Assay cartridges and methods of using the same |
| US9081001B2 (en) * | 2012-05-15 | 2015-07-14 | Wellstat Diagnostics, Llc | Diagnostic systems and instruments |
| US20140322706A1 (en) | 2012-10-24 | 2014-10-30 | Jon Faiz Kayyem | Integrated multipelx target analysis |
| JP1628115S (https=) | 2012-10-24 | 2019-04-01 | ||
| EP2932268A4 (en) * | 2012-12-17 | 2016-10-19 | Leukodx Ltd | SYSTEMS AND METHOD FOR RECOGNIZING A BIOLOGICAL CONDITION |
| CN104919035B (zh) | 2012-12-21 | 2017-08-11 | 精密公司 | 便携式荧光检测系统和微测定盒 |
| EP3549674B1 (en) | 2012-12-21 | 2020-08-12 | PerkinElmer Health Sciences, Inc. | Low elasticity films for microfluidic use |
| WO2014100732A1 (en) | 2012-12-21 | 2014-06-26 | Micronics, Inc. | Fluidic circuits and related manufacturing methods |
| US10441951B2 (en) | 2013-03-14 | 2019-10-15 | Siemens Healthcare Diagnostics Inc. | Microfluidic chip with sealed on-board reagent |
| CN107866286A (zh) | 2013-03-15 | 2018-04-03 | 金马克诊断股份有限公司 | 用于操纵可变形流体容器的系统、方法和设备 |
| JP6484222B2 (ja) | 2013-05-07 | 2019-03-13 | マイクロニクス, インコーポレイテッド | 核酸の調製および分析のためのデバイス |
| EP2994750B1 (en) | 2013-05-07 | 2020-08-12 | PerkinElmer Health Sciences, Inc. | Microfluidic devices and methods for performing serum separation and blood cross-matching |
| JP6472788B2 (ja) | 2013-05-07 | 2019-02-20 | マイクロニクス, インコーポレイテッド | 粘土鉱物およびアルカリ性溶液を使用して核酸含有試料を調製するための方法 |
| GB2516669B (en) * | 2013-07-29 | 2015-09-09 | Atlas Genetics Ltd | A method for processing a liquid sample in a fluidic cartridge |
| US9498778B2 (en) | 2014-11-11 | 2016-11-22 | Genmark Diagnostics, Inc. | Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system |
| USD881409S1 (en) | 2013-10-24 | 2020-04-14 | Genmark Diagnostics, Inc. | Biochip cartridge |
| US9937239B2 (en) * | 2014-05-21 | 2018-04-10 | The Johns Hopkins University | Preservation and reconstitution of cell-free protein expression systems |
| DK3152291T3 (da) * | 2014-06-09 | 2021-10-18 | Somnio Global Holdings Llc | Fremgangsmåder og indretninger til kapillar-understøttet vitrificering |
| EP3154693B1 (en) | 2014-06-11 | 2021-11-03 | PerkinElmer Health Sciences, Inc. | Method for performing a sample assay with a microfluidic cartridges with integrated assay controls |
| EP3015553A1 (de) * | 2014-10-30 | 2016-05-04 | Biotecon Diagnostics GmbH | Stabilisierte Reaktionsmischung |
| US9598722B2 (en) | 2014-11-11 | 2017-03-21 | Genmark Diagnostics, Inc. | Cartridge for performing assays in a closed sample preparation and reaction system |
| US10005080B2 (en) | 2014-11-11 | 2018-06-26 | Genmark Diagnostics, Inc. | Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation |
| WO2016168490A1 (en) * | 2015-04-15 | 2016-10-20 | University Of Washington | Isotachophoresis enhanced isothermal nucleic acid amplification |
| EP3288459B1 (en) | 2015-04-29 | 2023-09-20 | Revvity Health Sciences, Inc. | Specimen collection and delivery apparatus |
| US10124340B2 (en) | 2015-12-08 | 2018-11-13 | Electronics And Telecommunications Research Institute | Reagent storage device and bio-reaction apparatus including the same |
| JP6631420B2 (ja) | 2016-06-28 | 2020-01-15 | 株式会社デンソー | 光センサ |
| SG10202103252VA (en) | 2016-09-30 | 2021-05-28 | Tel Array Diagnostics Inc | Microfluidic device |
| GB201704760D0 (en) | 2017-01-05 | 2017-05-10 | Illumina Inc | Reagent nozzle sipper mixing system and method |
| CN112041659A (zh) * | 2018-02-06 | 2020-12-04 | 瓦罗贝克两合公司 | 微流体装置、系统、基础设施、其用途以及使用其用于基因工程改造的方法 |
| CN109673515A (zh) * | 2019-02-13 | 2019-04-26 | 广西壮族自治区药用植物园 | 羊齿天门冬超低温培养方法 |
| CN109792954A (zh) * | 2019-02-13 | 2019-05-24 | 广西壮族自治区药用植物园 | 石刁柏超低温保存培养方法 |
| CN109644874A (zh) * | 2019-02-13 | 2019-04-19 | 广西壮族自治区药用植物园 | 绣线菊超低温保存培养方法 |
| EP3953044A4 (en) * | 2019-04-08 | 2022-06-01 | Technion Research & Development Foundation Limited | MULTIPLEXED NETWORK OF NANOLITER DROPLET NETWORK DEVICES |
| US11856947B2 (en) | 2020-02-17 | 2024-01-02 | Cook Medical Technologies Llc | System for automated permeation of a biological material and method of using same |
| JP2022060807A (ja) * | 2020-10-05 | 2022-04-15 | キヤノンメディカルシステムズ株式会社 | 乾燥試薬、試薬キット、乾燥試薬の製造方法、分析方法及び核酸増幅方法 |
| WO2023113787A1 (en) * | 2021-12-15 | 2023-06-22 | Hewlett-Packard Development Company, L.P. | Microfluidic devices with dehydrated reagents |
| WO2025137109A1 (en) * | 2023-12-20 | 2025-06-26 | Abbott Point Of Care Inc. | Whole blood cmp in a dmf device without dilution |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007106579A2 (en) * | 2006-03-15 | 2007-09-20 | Micronics, Inc. | Integrated nucleic acid assays |
| WO2008147382A1 (en) * | 2006-09-27 | 2008-12-04 | Micronics, Inc. | Integrated microfluidic assay devices and methods |
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| DE2748132A1 (de) | 1977-10-27 | 1979-05-03 | Behringwerke Ag | Stabilisator fuer polysaccharid |
| US4457916A (en) | 1982-08-31 | 1984-07-03 | Asahi Kasei Kogyo Kabushiki Kaisha | Method for stabilizing Tumor Necrosis Factor and a stable aqueous solution or powder containing the same |
| ATE68524T1 (de) | 1985-07-09 | 1991-11-15 | Quadrant Bioresources Ltd | Beschuetzung von proteinen und aehnlichem. |
| US4762857A (en) | 1986-05-30 | 1988-08-09 | E. I. Du Pont De Nemours And Company | Trehalose as stabilizer and tableting excipient |
| US6127155A (en) | 1986-08-22 | 2000-10-03 | Roche Molecular Systems, Inc. | Stabilized thermostable nucleic acid polymerase compositions containing non-ionic polymeric detergents |
| GB8903593D0 (en) | 1989-02-16 | 1989-04-05 | Pafra Ltd | Storage of materials |
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| GB9010742D0 (en) * | 1990-05-14 | 1990-07-04 | Quadrant Bioresources Ltd | Stabilization of biological macromolecular substances |
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| JP5953229B2 (ja) | 2009-06-12 | 2016-07-20 | マイクロニクス, インコーポレイテッド | マイクロ流体デバイス内でオンボード試薬を脱水保存する組成物および方法 |
| WO2010144682A1 (en) | 2009-06-12 | 2010-12-16 | Micronics, Inc. | Rehydratable matrices for dry storage of taq polymerase in a microfluidic device |
-
2010
- 2010-06-10 JP JP2012515132A patent/JP5953229B2/ja active Active
- 2010-06-10 AU AU2010258716A patent/AU2010258716B2/en active Active
- 2010-06-10 EP EP10724663.9A patent/EP2440672B1/en active Active
- 2010-06-10 CN CN201080029480.4A patent/CN102803507B/zh active Active
- 2010-06-10 WO PCT/US2010/038141 patent/WO2010144683A2/en not_active Ceased
-
2011
- 2011-12-12 US US13/323,684 patent/US8921085B2/en active Active
-
2014
- 2014-11-26 US US14/554,720 patent/US9938571B2/en active Active
-
2016
- 2016-04-12 JP JP2016079321A patent/JP6097862B2/ja active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007106579A2 (en) * | 2006-03-15 | 2007-09-20 | Micronics, Inc. | Integrated nucleic acid assays |
| WO2008147382A1 (en) * | 2006-09-27 | 2008-12-04 | Micronics, Inc. | Integrated microfluidic assay devices and methods |
Non-Patent Citations (1)
| Title |
|---|
| Ramachandran S et al, Proceedings of the 1st Distributed Diagnosis and Home Healthcare (D2H2) Conference, 2006, pages 16 to 19 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012529888A (ja) | 2012-11-29 |
| CN102803507A (zh) | 2012-11-28 |
| US8921085B2 (en) | 2014-12-30 |
| CN102803507B (zh) | 2016-05-25 |
| EP2440672A2 (en) | 2012-04-18 |
| JP6097862B2 (ja) | 2017-03-15 |
| JP5953229B2 (ja) | 2016-07-20 |
| EP2440672B1 (en) | 2016-03-30 |
| WO2010144683A3 (en) | 2011-02-03 |
| AU2010258716A1 (en) | 2012-01-12 |
| US20120156750A1 (en) | 2012-06-21 |
| JP2016127869A (ja) | 2016-07-14 |
| US20150152481A1 (en) | 2015-06-04 |
| WO2010144683A2 (en) | 2010-12-16 |
| US9938571B2 (en) | 2018-04-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| PC | Assignment registered |
Owner name: PERKINELMER HEALTH SCIENCES, INC. Free format text: FORMER OWNER(S): MICRONICS, INC. |
|
| HB | Alteration of name in register |
Owner name: REVVITY HEALTH SCIENCES, INC. Free format text: FORMER NAME(S): PERKINELMER HEALTH SCIENCES, INC. |