AU2010242910B2 - Pyrido [4,3-b] indoles and methods of use - Google Patents

Pyrido [4,3-b] indoles and methods of use Download PDF

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Publication number
AU2010242910B2
AU2010242910B2 AU2010242910A AU2010242910A AU2010242910B2 AU 2010242910 B2 AU2010242910 B2 AU 2010242910B2 AU 2010242910 A AU2010242910 A AU 2010242910A AU 2010242910 A AU2010242910 A AU 2010242910A AU 2010242910 B2 AU2010242910 B2 AU 2010242910B2
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compound
unsubstituted
salt
substituted
solvate
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AU2010242910A1 (en
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Sarvajit Chakravarty
Rajendra Parasmal Jain
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Medivation Technologies LLC
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Medivation Technologies LLC
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU2010242910A 2009-04-29 2010-04-29 Pyrido [4,3-b] indoles and methods of use Ceased AU2010242910B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2013203575A AU2013203575A1 (en) 2009-04-29 2013-04-10 Pyrido [4,3-b] indoles and methods of use

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN1136/MUM/2009 2009-04-29
IN1136MU2009 2009-04-29
US18126209P 2009-05-26 2009-05-26
US61/181,262 2009-05-26
PCT/US2010/033053 WO2010127177A1 (en) 2009-04-29 2010-04-29 Pyrido [4,3-b] indoles and methods of use

Related Child Applications (1)

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AU2013203575A Division AU2013203575A1 (en) 2009-04-29 2013-04-10 Pyrido [4,3-b] indoles and methods of use

Publications (2)

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AU2010242910A1 AU2010242910A1 (en) 2011-11-17
AU2010242910B2 true AU2010242910B2 (en) 2015-11-12

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AU2010242910A Ceased AU2010242910B2 (en) 2009-04-29 2010-04-29 Pyrido [4,3-b] indoles and methods of use

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US (2) US9255094B2 (enExample)
EP (1) EP2424364A4 (enExample)
JP (1) JP5711725B2 (enExample)
CN (1) CN102480955B (enExample)
AU (1) AU2010242910B2 (enExample)
BR (1) BRPI1006602A2 (enExample)
CA (1) CA2760541A1 (enExample)
WO (1) WO2010127177A1 (enExample)

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CA2829045A1 (en) 2011-02-18 2012-08-23 Medivation Technologies, Inc. Compounds and methods for treatment of hypertension
US20140155384A1 (en) 2011-02-18 2014-06-05 Medivation Technologies, Inc. Compounds and methods of treating diabetes
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RU2490268C2 (ru) * 2011-11-10 2013-08-20 Федеральное Государственное Бюджетное Учреждение Науки Институт Физиологически Активных Веществ Российской Академии Наук (Ифав Ран) ХЛОРГИДРАТЫ ФТОРСОДЕРЖАЩИХ ЗАМЕЩЕННЫХ 5-[2-(ПИРИД-3-ИЛ)-ЭТИЛ]-2,3,4,5-ТЕТРАГИДРО-1Н-ПИРИДО[4,3-b]ИНДОЛОВ, В КАЧЕСТВЕ СРЕДСТВ СНИЖЕНИЯ НЕКОНТРОЛИРУЕМОЙ АГРЕГАЦИИ БЕЛКОВ В НЕРВНОЙ СИСТЕМЕ, ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ИХ ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ
EP2785720B1 (en) * 2011-11-29 2017-08-09 Nanjing Allgen Pharma Co. Ltd. Heterocyclic amides compounds which are hdac6 inhibitors and used as anti-tumoral agents
WO2014031167A1 (en) * 2012-08-22 2014-02-27 Medivation Technologies, Inc. Compounds and methods for treatment of hypertension
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US9907786B2 (en) 2014-10-21 2018-03-06 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof
US10092550B2 (en) 2014-10-21 2018-10-09 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing curcumin, harmine, and isovanillin components, and methods of use thereof
US12129265B2 (en) 2020-07-21 2024-10-29 Ankh Life Sciences Limited Therapeutic agents and uses thereof
KR20230171634A (ko) * 2022-06-14 2023-12-21 주식회사 레고켐 바이오사이언스 엑토뉴클레오티드 피로포스파타아제 포스포디에스터라아제-1 저해 화합물 및 이를 함유하는 약제학적 조성물

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JP5711725B2 (ja) 2015-05-07
US9255094B2 (en) 2016-02-09
JP2012525430A (ja) 2012-10-22
AU2010242910A1 (en) 2011-11-17
CN102480955A (zh) 2012-05-30
US20130190328A1 (en) 2013-07-25
EP2424364A1 (en) 2012-03-07
BRPI1006602A2 (pt) 2019-01-15
HK1170380A1 (en) 2013-03-01
CA2760541A1 (en) 2010-11-04
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