AU2009333815B2 - Stroke-generated angiogenesis enhancers and uses thereof - Google Patents

Stroke-generated angiogenesis enhancers and uses thereof Download PDF

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Publication number
AU2009333815B2
AU2009333815B2 AU2009333815A AU2009333815A AU2009333815B2 AU 2009333815 B2 AU2009333815 B2 AU 2009333815B2 AU 2009333815 A AU2009333815 A AU 2009333815A AU 2009333815 A AU2009333815 A AU 2009333815A AU 2009333815 B2 AU2009333815 B2 AU 2009333815B2
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brain
stroke
angiogenesis
integrin
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AU2009333815A
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AU2009333815A1 (en
Inventor
Gregory J. Bix
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Texas A&M University System
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Texas A&M University System
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4725Proteoglycans, e.g. aggreccan
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546Integrin superfamily
    • C07K14/7055Integrin beta1-subunit-containing molecules, e.g. CD29, CD49
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2009333815A 2008-12-31 2009-12-31 Stroke-generated angiogenesis enhancers and uses thereof Active AU2009333815B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20406408P 2008-12-31 2008-12-31
US61/204,064 2008-12-31
PCT/US2009/006758 WO2010077364A2 (en) 2008-12-31 2009-12-31 Stroke-generated angiogenesis enhancers and uses thereof

Publications (2)

Publication Number Publication Date
AU2009333815A1 AU2009333815A1 (en) 2011-08-11
AU2009333815B2 true AU2009333815B2 (en) 2016-02-18

Family

ID=42174116

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009333815A Active AU2009333815B2 (en) 2008-12-31 2009-12-31 Stroke-generated angiogenesis enhancers and uses thereof

Country Status (12)

Country Link
US (1) US8466105B2 (ja)
EP (1) EP2373328B1 (ja)
JP (1) JP5591825B2 (ja)
KR (1) KR101746749B1 (ja)
CN (2) CN104208659A (ja)
AU (1) AU2009333815B2 (ja)
BR (1) BRPI0924061B8 (ja)
CA (1) CA2748811C (ja)
ES (1) ES2524366T3 (ja)
MX (1) MX2011007108A (ja)
RU (1) RU2011131772A (ja)
WO (1) WO2010077364A2 (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011085136A2 (en) 2010-01-06 2011-07-14 Elan Pharmaceuticals, Inc. Use of perlecan domain v in treating amyloidogenic disease
EP2588122B1 (en) 2010-07-01 2016-03-23 The Texas A&M University System Perlecan domain v protects, repairs and restores ischemic brain stroke injury and motor function
WO2019118689A1 (en) * 2017-12-13 2019-06-20 University Of Kentucky Research Foundation Compositions and methods for enhancing neuro-repair
CN108715833B (zh) * 2018-06-01 2021-09-14 天晴干细胞股份有限公司 一种负载血小板裂解液的微球制备方法
IL300114A (en) * 2020-07-24 2023-03-01 Stream Biomedical Inc Use of PERLECAN and its fractions to reduce the risk of death in stroke patients

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6821947B2 (en) * 2001-12-04 2004-11-23 Thomas Jefferson University Endorepellin: methods and compositions for inhibiting angiogenesis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Clarke D. et al, ENDOREPELLIN AND ENDOSTATIN AFFECT THE NEUROVASCULAR UNIT IN VITRO, Journal of Neurochemistry, 2008 first published online January 31, Vol. 104, supplement s1, pg. 77, abstract OP02-04 *

Also Published As

Publication number Publication date
MX2011007108A (es) 2011-09-28
ES2524366T3 (es) 2014-12-05
WO2010077364A3 (en) 2010-10-21
EP2373328A2 (en) 2011-10-12
JP5591825B2 (ja) 2014-09-17
BRPI0924061A2 (pt) 2015-07-07
WO2010077364A2 (en) 2010-07-08
CA2748811A1 (en) 2010-07-08
JP2012514036A (ja) 2012-06-21
CN102355905A (zh) 2012-02-15
CA2748811C (en) 2019-07-16
KR20110127131A (ko) 2011-11-24
AU2009333815A1 (en) 2011-08-11
CN104208659A (zh) 2014-12-17
BRPI0924061B1 (pt) 2020-11-24
RU2011131772A (ru) 2013-02-10
US8466105B2 (en) 2013-06-18
KR101746749B1 (ko) 2017-06-13
BRPI0924061B8 (pt) 2021-05-25
US20100168025A1 (en) 2010-07-01
EP2373328B1 (en) 2014-08-20

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