AU2009324534B2 - GNAQ targeted dsRNA compositions and methods for inhibiting expression - Google Patents

GNAQ targeted dsRNA compositions and methods for inhibiting expression Download PDF

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AU2009324534B2
AU2009324534B2 AU2009324534A AU2009324534A AU2009324534B2 AU 2009324534 B2 AU2009324534 B2 AU 2009324534B2 AU 2009324534 A AU2009324534 A AU 2009324534A AU 2009324534 A AU2009324534 A AU 2009324534A AU 2009324534 B2 AU2009324534 B2 AU 2009324534B2
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seq
sense
antis
antisense strand
sense strand
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AU2009324534A1 (en
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David Bumcrot
Jared Gollob
Gregory Hinkle
Ivanka Toudjarska
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Alnylam Pharmaceuticals Inc
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N2320/00—Applications; Uses
    • C12N2320/50—Methods for regulating/modulating their activity
    • C12N2320/51—Methods for regulating/modulating their activity modulating the chemical stability, e.g. nuclease-resistance

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2009324534A 2008-12-10 2009-12-10 GNAQ targeted dsRNA compositions and methods for inhibiting expression Active AU2009324534B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2015204362A AU2015204362A1 (en) 2008-12-10 2015-07-16 GNAQ targeted dsRNA compositions and methods for inhibiting expression

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US12125308P 2008-12-10 2008-12-10
US61/121,253 2008-12-10
US18554309P 2009-06-09 2009-06-09
US61/185,543 2009-06-09
US24478009P 2009-09-22 2009-09-22
US61/244,780 2009-09-22
PCT/US2009/067581 WO2010068816A1 (en) 2008-12-10 2009-12-10 Gnaq targeted dsrna compositions and methods for inhibiting expression

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AU2009324534A1 AU2009324534A1 (en) 2011-07-14
AU2009324534B2 true AU2009324534B2 (en) 2015-07-30

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US (6) US8324368B2 (enExample)
EP (2) EP2373382B1 (enExample)
JP (2) JP5855462B2 (enExample)
AU (1) AU2009324534B2 (enExample)
CA (1) CA2746514C (enExample)
NZ (1) NZ593618A (enExample)
WO (1) WO2010068816A1 (enExample)

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US20130012570A1 (en) 2013-01-10
JP2012511332A (ja) 2012-05-24
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