AU2009316710B2 - Dimeric 1-arylpyrazole derivatives - Google Patents

Dimeric 1-arylpyrazole derivatives Download PDF

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Publication number
AU2009316710B2
AU2009316710B2 AU2009316710A AU2009316710A AU2009316710B2 AU 2009316710 B2 AU2009316710 B2 AU 2009316710B2 AU 2009316710 A AU2009316710 A AU 2009316710A AU 2009316710 A AU2009316710 A AU 2009316710A AU 2009316710 B2 AU2009316710 B2 AU 2009316710B2
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Australia
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haloalkyl
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AU2009316710A
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AU2009316710A1 (en
Inventor
Charles Q. Meng
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Boehringer Ingelheim Animal Health USA Inc
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Boehringer Ingelheim Animal Health USA Inc
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Application filed by Boehringer Ingelheim Animal Health USA Inc filed Critical Boehringer Ingelheim Animal Health USA Inc
Publication of AU2009316710A1 publication Critical patent/AU2009316710A1/en
Assigned to MERIAL, INC. reassignment MERIAL, INC. Request for Assignment Assignors: MERIAL LIMITED
Application granted granted Critical
Publication of AU2009316710B2 publication Critical patent/AU2009316710B2/en
Assigned to Boehringer Ingelheim Animal Health USA Inc. reassignment Boehringer Ingelheim Animal Health USA Inc. Request for Assignment Assignors: MERIAL, INC.
Active legal-status Critical Current
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pest Control & Pesticides (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Agronomy & Crop Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2009316710A 2008-11-19 2009-11-18 Dimeric 1-arylpyrazole derivatives Active AU2009316710B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11602108P 2008-11-19 2008-11-19
US61/116,021 2008-11-19
PCT/US2009/064981 WO2010059719A2 (en) 2008-11-19 2009-11-18 Dimeric 1-arylpyrazole derivatives

Publications (2)

Publication Number Publication Date
AU2009316710A1 AU2009316710A1 (en) 2010-05-27
AU2009316710B2 true AU2009316710B2 (en) 2015-08-06

Family

ID=42034586

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009316710A Active AU2009316710B2 (en) 2008-11-19 2009-11-18 Dimeric 1-arylpyrazole derivatives

Country Status (12)

Country Link
US (1) US8642636B2 (cg-RX-API-DMAC7.html)
EP (1) EP2364300B1 (cg-RX-API-DMAC7.html)
JP (1) JP2012509338A (cg-RX-API-DMAC7.html)
CN (1) CN102264706A (cg-RX-API-DMAC7.html)
AU (1) AU2009316710B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0922042B1 (cg-RX-API-DMAC7.html)
CA (2) CA2952443C (cg-RX-API-DMAC7.html)
EA (1) EA020923B1 (cg-RX-API-DMAC7.html)
ES (1) ES2605811T3 (cg-RX-API-DMAC7.html)
MX (1) MX2011005214A (cg-RX-API-DMAC7.html)
NZ (1) NZ592985A (cg-RX-API-DMAC7.html)
WO (1) WO2010059719A2 (cg-RX-API-DMAC7.html)

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BR112013029201B1 (pt) 2011-05-13 2022-08-09 Array Biopharma Inc Compostos de pirrolidinil ureia e pirrolidinil tioureia, seu processo de preparação, seu uso e composições farmacêuticas
CA2891334C (en) 2012-11-13 2021-10-19 Array Biopharma Inc. Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain
WO2014078328A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. N-bicyclic aryl,n'-pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
RU2677667C2 (ru) 2012-11-13 2019-01-18 Эррэй Биофарма Инк. Соединения n-пирролидинилмочевины, n'-пиразолилмочевины, тиомочевины, гуанидина и цианогуанидина как ингибиторы киназы trka
WO2014078322A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. Thiazolyl and oxazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
US9790210B2 (en) 2012-11-13 2017-10-17 Array Biopharma Inc. N-(monocyclic aryl),N'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
WO2014078331A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. N-(arylalkyl)-n'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
WO2014078417A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. Pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
WO2014078408A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. Bicyclic heteroaryl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
US9790178B2 (en) 2012-11-13 2017-10-17 Array Biopharma Inc. Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
WO2014078378A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
JP2016164125A (ja) * 2013-07-02 2016-09-08 国立大学法人帯広畜産大学 バベシア症の治療剤及び予防剤
RU2719489C2 (ru) 2014-05-15 2020-04-17 Эррэй Биофарма Инк. 1-((3S,4R)-4-(3-ФТОРФЕНИЛ)-1-(2-МЕТОКСИЭТИЛ)ПИРРОЛИДИН-3-ИЛ)-3-(4-МЕТИЛ-3-(2-МЕТИЛПИРИМИДИН-5-ИЛ)-1-ФЕНИЛ-1Н-ПИРАЗОЛ-5-ИЛ)МОЧЕВИНА В КАЧЕСТВЕ ИНГИБИТОРА TrkA КИНАЗЫ
WO2017195173A1 (en) 2016-05-12 2017-11-16 Verdesian Life Sciences, U.S., Llc Compositions for controlling enzyme-induced urea decomposition
MY201375A (en) 2017-03-28 2024-02-20 Verdesian Life Sciences Us Llc Triarylmethane compounds for controlling enzyme-induced urea decomposition
JP7504882B2 (ja) 2018-11-06 2024-06-24 コルテバ アグリサイエンス エルエルシー ピリジンカルボン酸エステル除草剤とクロキントセットとを含む薬害が軽減された組成物
ES3013124T3 (en) * 2018-11-06 2025-04-11 Corteva Agriscience Llc Compositions comprising pyridine carboxylate herbicides and azole carboxylate safeners
WO2020096936A1 (en) 2018-11-07 2020-05-14 Dow Agrosciences Llc Compositions comprising pyridine carboxylate herbicides and 4-hydroxyphenyl-pyruvate dioxygenase (hppd) inhibitor herbicides
PL3876733T3 (pl) 2018-11-07 2025-11-03 Corteva Agriscience Llc Kompozycje zawierające herbicydy pirydynokarboksylanowe z herbicydami jako inhibitorami fotosystemu ii i opcjonalnie herbicydami jako inhibitorami hppd
ES3037961T3 (en) 2018-11-07 2025-10-08 Corteva Agriscience Llc Compositions comprising pyridine carboxylate herbicides with acetolactate synthase (als) inhibitor herbicides
CA3118677A1 (en) 2018-11-07 2020-05-14 Corteva Agriscience Llc Compositions comprising a pyridine carboxylate herbicide and protoporphyrinogen oxidase (protox) inhibitor herbicides
AU2019387370A1 (en) 2018-11-30 2021-06-10 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
EP4185585A1 (en) 2020-07-24 2023-05-31 Elanco Us Inc. Process for making an isoxazoline compound and intermediate thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966900A (en) * 1969-03-12 1976-06-29 Airwick Industries, Inc. Evaporator system comprising a stabilized pesticidal phosphoric acid ester and method for stabilizing such ester enclosed in an evaporator
US20070275976A1 (en) * 2004-06-26 2007-11-29 Stefan Schnatterer N-phenylpyrazole derivatives as pesticides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU784798B2 (en) * 1999-12-02 2006-06-22 Boehringer Ingelheim Animal Health USA Inc. Control of arthropods in animals
US7262214B2 (en) * 2003-02-26 2007-08-28 Merial Limited 1-N-arylpyrazole derivatives in prevention of arthropod-borne and mosquito-borne diseases

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966900A (en) * 1969-03-12 1976-06-29 Airwick Industries, Inc. Evaporator system comprising a stabilized pesticidal phosphoric acid ester and method for stabilizing such ester enclosed in an evaporator
US20070275976A1 (en) * 2004-06-26 2007-11-29 Stefan Schnatterer N-phenylpyrazole derivatives as pesticides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Ahluwalia, V. K., et al, Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1997, 36B, 1059-1061 *
Finar, I. L., et al, Journal of the Chemical Society, 1959, 1819-21 *
Nivorozhkin, A. L., et al, Journal of the Chemical Society, Dalton Transactions, 1996, 1215-1221 *

Also Published As

Publication number Publication date
BRPI0922042A2 (pt) 2016-11-01
CA2743553A1 (en) 2010-05-27
CN102264706A (zh) 2011-11-30
EP2364300A2 (en) 2011-09-14
WO2010059719A3 (en) 2010-11-18
CA2952443C (en) 2019-04-02
HK1160852A1 (en) 2012-08-17
EA020923B1 (ru) 2015-02-27
CA2743553C (en) 2017-03-14
EP2364300B1 (en) 2016-10-19
ES2605811T3 (es) 2017-03-16
US20110245157A1 (en) 2011-10-06
BRPI0922042B1 (pt) 2020-01-28
WO2010059719A2 (en) 2010-05-27
AU2009316710A1 (en) 2010-05-27
EA201100800A1 (ru) 2011-12-30
JP2012509338A (ja) 2012-04-19
CA2952443A1 (en) 2010-05-27
US8642636B2 (en) 2014-02-04
NZ592985A (en) 2013-04-26
MX2011005214A (es) 2011-06-01

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Legal Events

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PC1 Assignment before grant (sect. 113)

Owner name: MERIAL, INC.

Free format text: FORMER APPLICANT(S): MERIAL LIMITED

FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.

Free format text: FORMER OWNER(S): MERIAL, INC.