AU2009284692B2 - Monoclonal antibody STRO-4 - Google Patents

Monoclonal antibody STRO-4 Download PDF

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Publication number
AU2009284692B2
AU2009284692B2 AU2009284692A AU2009284692A AU2009284692B2 AU 2009284692 B2 AU2009284692 B2 AU 2009284692B2 AU 2009284692 A AU2009284692 A AU 2009284692A AU 2009284692 A AU2009284692 A AU 2009284692A AU 2009284692 B2 AU2009284692 B2 AU 2009284692B2
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AU
Australia
Prior art keywords
cells
hsp
90beta
stro
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2009284692A
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English (en)
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AU2009284692A1 (en
Inventor
Stan Gronthos
Andrew Christopher William Zannettino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mesoblast Inc
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Mesoblast Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mesoblast Inc filed Critical Mesoblast Inc
Publication of AU2009284692A1 publication Critical patent/AU2009284692A1/en
Assigned to MESOBLAST, INC. reassignment MESOBLAST, INC. Amend patent request/document other than specification (104) Assignors: ANGIOBLAST SYSTEMS, INC.
Application granted granted Critical
Publication of AU2009284692B2 publication Critical patent/AU2009284692B2/en
Priority to AU2016203436A priority Critical patent/AU2016203436A1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4703—Regulators; Modulating activity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AU2009284692A 2008-08-18 2009-08-18 Monoclonal antibody STRO-4 Active AU2009284692B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2016203436A AU2016203436A1 (en) 2008-08-18 2016-05-25 Monoclonal antibody STRO-4

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18934908P 2008-08-18 2008-08-18
US61/189,349 2008-08-18
PCT/AU2009/001060 WO2010019997A1 (en) 2008-08-18 2009-08-18 Monoclonal antibody stro-4

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2016203436A Division AU2016203436A1 (en) 2008-08-18 2016-05-25 Monoclonal antibody STRO-4

Publications (2)

Publication Number Publication Date
AU2009284692A1 AU2009284692A1 (en) 2010-02-25
AU2009284692B2 true AU2009284692B2 (en) 2016-02-25

Family

ID=41706760

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2009284692A Active AU2009284692B2 (en) 2008-08-18 2009-08-18 Monoclonal antibody STRO-4
AU2016203436A Abandoned AU2016203436A1 (en) 2008-08-18 2016-05-25 Monoclonal antibody STRO-4

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2016203436A Abandoned AU2016203436A1 (en) 2008-08-18 2016-05-25 Monoclonal antibody STRO-4

Country Status (11)

Country Link
US (2) US9090678B2 (https=)
EP (2) EP2324359B1 (https=)
JP (1) JP5826629B2 (https=)
KR (1) KR101713343B1 (https=)
CN (3) CN102257388B (https=)
AU (2) AU2009284692B2 (https=)
CA (1) CA2734210C (https=)
ES (1) ES2707274T3 (https=)
SG (1) SG10201601279SA (https=)
TR (1) TR201900975T4 (https=)
WO (1) WO2010019997A1 (https=)

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JP7034949B2 (ja) 2016-05-25 2022-03-14 テルモ ビーシーティー、インコーポレーテッド 細胞の増殖
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
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US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
CN117247899A (zh) 2017-03-31 2023-12-19 泰尔茂比司特公司 细胞扩增
CN110684105B (zh) * 2019-09-11 2021-01-29 江苏莱森生物科技研究院有限公司 一种抗hsp90单克隆抗体及试剂盒
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Also Published As

Publication number Publication date
JP5826629B2 (ja) 2015-12-02
CA2734210A1 (en) 2010-02-25
ES2707274T3 (es) 2019-04-03
KR20110055605A (ko) 2011-05-25
CA2734210C (en) 2018-03-27
JP2012500010A (ja) 2012-01-05
TR201900975T4 (tr) 2019-02-21
CN106995797A (zh) 2017-08-01
EP3121597A1 (en) 2017-01-25
EP2324359A1 (en) 2011-05-25
KR101713343B1 (ko) 2017-03-22
CN104678106B (zh) 2016-12-07
US20110189696A1 (en) 2011-08-04
EP2324359A4 (en) 2013-04-17
AU2009284692A1 (en) 2010-02-25
CN106995797B (zh) 2021-04-30
EP2324359B1 (en) 2018-10-31
AU2016203436A1 (en) 2016-06-16
CN104678106A (zh) 2015-06-03
SG10201601279SA (en) 2016-03-30
US9090678B2 (en) 2015-07-28
US20150307608A1 (en) 2015-10-29
US9815896B2 (en) 2017-11-14
CN102257388A (zh) 2011-11-23
WO2010019997A1 (en) 2010-02-25
CN102257388B (zh) 2015-03-18

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