AU2009273130B2 - Novel compositions and methods - Google Patents

Novel compositions and methods Download PDF

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Publication number
AU2009273130B2
AU2009273130B2 AU2009273130A AU2009273130A AU2009273130B2 AU 2009273130 B2 AU2009273130 B2 AU 2009273130B2 AU 2009273130 A AU2009273130 A AU 2009273130A AU 2009273130 A AU2009273130 A AU 2009273130A AU 2009273130 B2 AU2009273130 B2 AU 2009273130B2
Authority
AU
Australia
Prior art keywords
seq
polypeptide
sequence
tuberculosis
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2009273130A
Other languages
English (en)
Other versions
AU2009273130A1 (en
Inventor
James Brown
Pascal Mettens
Dennis Murphy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Glaxo Group Ltd
Original Assignee
GlaxoSmithKline Biologicals SA
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GlaxoSmithKline Biologicals SA, Glaxo Group Ltd filed Critical GlaxoSmithKline Biologicals SA
Publication of AU2009273130A1 publication Critical patent/AU2009273130A1/en
Application granted granted Critical
Publication of AU2009273130B2 publication Critical patent/AU2009273130B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
AU2009273130A 2008-07-25 2009-07-24 Novel compositions and methods Ceased AU2009273130B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8372008P 2008-07-25 2008-07-25
US61/083,720 2008-07-25
PCT/EP2009/059580 WO2010010177A1 (en) 2008-07-25 2009-07-24 Novel compositions and methods

Publications (2)

Publication Number Publication Date
AU2009273130A1 AU2009273130A1 (en) 2010-01-28
AU2009273130B2 true AU2009273130B2 (en) 2014-10-16

Family

ID=41217660

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009273130A Ceased AU2009273130B2 (en) 2008-07-25 2009-07-24 Novel compositions and methods

Country Status (24)

Country Link
US (2) US20110117119A1 (pt)
EP (1) EP2315773B1 (pt)
JP (1) JP5873332B2 (pt)
KR (1) KR20110044883A (pt)
CN (1) CN102164952B (pt)
AU (1) AU2009273130B2 (pt)
BR (1) BRPI0916703A2 (pt)
CA (1) CA2731499C (pt)
CO (1) CO6341637A2 (pt)
CY (1) CY1118200T1 (pt)
DK (1) DK2315773T3 (pt)
EA (1) EA024826B1 (pt)
ES (1) ES2602430T3 (pt)
HR (1) HRP20161458T1 (pt)
HU (1) HUE031044T2 (pt)
IL (1) IL210559A0 (pt)
LT (1) LT2315773T (pt)
MX (1) MX2011000983A (pt)
PL (1) PL2315773T3 (pt)
PT (1) PT2315773T (pt)
SG (1) SG192456A1 (pt)
SI (1) SI2315773T1 (pt)
UA (1) UA107330C2 (pt)
WO (1) WO2010010177A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1350546A (zh) * 1998-11-04 2002-05-22 Isis创新有限公司 结核诊断测验
KR20110060891A (ko) 2008-07-25 2011-06-08 글락소스미스클라인 바이오로지칼즈 에스.에이. 신규한 조성물 및 방법
CN106866801A (zh) 2008-07-25 2017-06-20 葛兰素史密丝克莱恩生物有限公司 结核病rv2386c蛋白、组合物及其用途
EP2156945A1 (en) 2008-08-13 2010-02-24 Novelis Inc. Clad automotive sheet product
TR201903223T4 (tr) 2009-04-24 2019-03-21 Statens Seruminstitut Reaktivasyonu önlemek üzere bir tüberküloz TB aşısı.
UA110103C2 (uk) 2010-01-27 2015-11-25 Ґлаксосмітклайн Байолоджікалз С.А. Модифікований туберкульозний антиген
EP3049973B1 (en) 2013-09-27 2018-08-08 Codexis, Inc. Automated screening of enzyme variants
EP3049979B1 (en) 2013-09-27 2020-01-01 Codexis, Inc. Structure based predictive modeling
GB201405921D0 (en) * 2014-04-02 2014-05-14 Glaxosmithkline Biolog Sa Novel methods for inducing an immune response
CN106546737A (zh) * 2016-10-24 2017-03-29 广州迪澳医疗科技有限公司 一种体外检测活动性结核的方法
GB201621686D0 (en) 2016-12-20 2017-02-01 Glaxosmithkline Biologicals Sa Novel methods for inducing an immune response
GB201707700D0 (en) 2017-05-12 2017-06-28 Glaxosmithkline Biologicals Sa Dried composition
GB2600653B (en) 2017-05-30 2022-11-02 Glaxosmithkline Biologicals Sa Novel methods
EP3717001A1 (en) 2017-12-01 2020-10-07 GlaxoSmithKline Biologicals S.A. Saponin purification
BR112021024363A2 (pt) 2019-06-05 2022-03-22 Glaxosmithkline Biologicals Sa Purificação de saponina

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998053075A2 (en) * 1997-05-20 1998-11-26 Corixa Corporation Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
WO2001062893A2 (en) * 2000-02-25 2001-08-30 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
US20040086523A1 (en) * 2000-06-20 2004-05-06 Yasir Skeiky Fusion proteins of mycobacterium tuberculosis
US20040197896A1 (en) * 2001-02-22 2004-10-07 Stewart Cole Comparative mycobacterial geneomics as a tool for identifying targets for the diagnosis, prophylaxis or treatment of mycobacterioses
WO2008007942A1 (en) * 2006-07-10 2008-01-17 Het Nederlands Kanker Instituut Means and methods for manipulating sequential phagolysomal-cytosolic translocation of mycobacteria, and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ507378A (en) * 1998-04-07 2002-12-20 Corixa Corp Fusion proteins of mycobacterium tuberculosis antigens and their uses
JP3840596B2 (ja) * 2001-01-08 2006-11-01 アイシス・イノベーション・リミテッド ミコバクテリア感染のための治療の効力を決定するためのアッセイ法
US20030236393A1 (en) * 2002-03-22 2003-12-25 United States Of America Dept Of Vetrans Affairs Virulence genes of M. marinum and M. tuberculosis
WO2006009838A2 (en) * 2004-06-17 2006-01-26 Beckman Coulter, Inc. Mycobacterium tuberculosis epitopes and methods of use thereof
KR20150036658A (ko) 2005-04-29 2015-04-07 글락소스미스클라인 바이오로지칼즈 에스.에이. 결핵균 감염을 예방 또는 치료하기 위한 신규한 방법
EP2380590A3 (en) * 2005-06-23 2012-08-22 Statens Serum Institut Improved tuberculosis vaccines
WO2008140478A2 (en) * 2006-11-01 2008-11-20 Immport Therapeutics, Inc. Compositions and methods for immunodominant antigens
TR201903223T4 (tr) * 2009-04-24 2019-03-21 Statens Seruminstitut Reaktivasyonu önlemek üzere bir tüberküloz TB aşısı.
UA110103C2 (uk) 2010-01-27 2015-11-25 Ґлаксосмітклайн Байолоджікалз С.А. Модифікований туберкульозний антиген

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998053075A2 (en) * 1997-05-20 1998-11-26 Corixa Corporation Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
WO2001062893A2 (en) * 2000-02-25 2001-08-30 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
US20040086523A1 (en) * 2000-06-20 2004-05-06 Yasir Skeiky Fusion proteins of mycobacterium tuberculosis
US20040197896A1 (en) * 2001-02-22 2004-10-07 Stewart Cole Comparative mycobacterial geneomics as a tool for identifying targets for the diagnosis, prophylaxis or treatment of mycobacterioses
WO2008007942A1 (en) * 2006-07-10 2008-01-17 Het Nederlands Kanker Instituut Means and methods for manipulating sequential phagolysomal-cytosolic translocation of mycobacteria, and uses thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
FORTUNE S M ET AL (2005) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 102, pages 10676-10681 *
MCLAUGHLIN BRYANT ET AL (2007) PLOS PATHOGENS, vol. 3, pages 1051-1061 *
MUSTAFA A S ET AL (2006) INFECTION AND IMMUNITY, vol. 74, pages 4566-4572 *
REED S ET AL (2005) MICROBES AND INFECTION, vol. 7, pages 922-931 *

Also Published As

Publication number Publication date
PT2315773T (pt) 2016-11-23
HRP20161458T1 (hr) 2016-12-16
BRPI0916703A2 (pt) 2019-12-24
EA024826B1 (ru) 2016-10-31
CN102164952B (zh) 2016-05-25
CY1118200T1 (el) 2017-06-28
MX2011000983A (es) 2011-03-02
ES2602430T3 (es) 2017-02-21
US20110117119A1 (en) 2011-05-19
JP2011528895A (ja) 2011-12-01
US20140178423A1 (en) 2014-06-26
SI2315773T1 (sl) 2016-12-30
CN102164952A (zh) 2011-08-24
CO6341637A2 (es) 2011-11-21
WO2010010177A1 (en) 2010-01-28
EA201100072A1 (ru) 2011-10-31
IL210559A0 (en) 2011-03-31
PL2315773T3 (pl) 2017-07-31
JP5873332B2 (ja) 2016-03-01
CA2731499C (en) 2017-01-10
SG192456A1 (en) 2013-08-30
UA107330C2 (uk) 2014-12-25
KR20110044883A (ko) 2011-05-02
US9795663B2 (en) 2017-10-24
EP2315773A1 (en) 2011-05-04
AU2009273130A1 (en) 2010-01-28
LT2315773T (lt) 2016-11-10
HUE031044T2 (en) 2017-06-28
EP2315773B1 (en) 2016-08-24
DK2315773T3 (en) 2016-12-12
CA2731499A1 (en) 2010-01-28

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired