AU2009226153B2 - Novel tyrosine kinase inhibitors - Google Patents
Novel tyrosine kinase inhibitors Download PDFInfo
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- AU2009226153B2 AU2009226153B2 AU2009226153A AU2009226153A AU2009226153B2 AU 2009226153 B2 AU2009226153 B2 AU 2009226153B2 AU 2009226153 A AU2009226153 A AU 2009226153A AU 2009226153 A AU2009226153 A AU 2009226153A AU 2009226153 B2 AU2009226153 B2 AU 2009226153B2
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Classifications
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- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
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- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Medicinal Chemistry (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3803208P | 2008-03-19 | 2008-03-19 | |
| US61/038,032 | 2008-03-19 | ||
| PCT/US2009/001691 WO2009117097A1 (en) | 2008-03-19 | 2009-03-18 | Novel tyrosine kinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2009226153A1 AU2009226153A1 (en) | 2009-09-24 |
| AU2009226153B2 true AU2009226153B2 (en) | 2014-02-20 |
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Family Applications (1)
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| AU2009226153A Ceased AU2009226153B2 (en) | 2008-03-19 | 2009-03-18 | Novel tyrosine kinase inhibitors |
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| Country | Link |
|---|---|
| US (1) | US8815906B2 (enExample) |
| EP (2) | EP2262807B1 (enExample) |
| JP (2) | JP5628145B2 (enExample) |
| CN (1) | CN102036990B (enExample) |
| AU (1) | AU2009226153B2 (enExample) |
| CA (1) | CA2718872C (enExample) |
| DK (1) | DK2262807T3 (enExample) |
| MX (1) | MX2010010272A (enExample) |
| WO (1) | WO2009117097A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9249147B2 (en) | 2008-03-19 | 2016-02-02 | Chembridge Corporation | Tyrosine kinase inhibitors |
| US9273055B2 (en) | 2008-03-19 | 2016-03-01 | Chembridge Corporation | Tyrosine kinase inhibitors |
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| BR112014011465A2 (pt) * | 2011-11-14 | 2017-05-09 | Tesaro Inc | modulação de determinadas quinases de tirosina |
| EP2842946B1 (en) * | 2012-04-24 | 2016-09-28 | Chugai Seiyaku Kabushiki Kaisha | Quinazolinedione derivative |
| WO2013161851A1 (ja) | 2012-04-24 | 2013-10-31 | 中外製薬株式会社 | ベンズアミド誘導体 |
| MX357043B (es) | 2012-07-04 | 2018-06-25 | Rhizen Pharmaceuticals Sa | Inhibidores selectivos de pi3k delta. |
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| HRP20200662T1 (hr) * | 2014-02-04 | 2020-10-02 | Astellas Pharma Inc. | Ljekoviti pripravak koji sadrži spoj diamino heterocikličkog karboksamida kao aktivni sastojak |
| AU2015247489B2 (en) * | 2014-04-17 | 2019-04-18 | Amgen Inc. | Polymorphic forms and co-crystals of a c-Met inhibitor |
| JP2017517552A (ja) | 2014-06-13 | 2017-06-29 | ジェネンテック， インコーポレイテッド | 抗癌剤耐性の治療及び防止方法 |
| BR112017019305A2 (pt) * | 2015-03-10 | 2018-05-08 | Aurigene Discovery Technologies Limited | compostos cíclicos terapêuticos como imunomoduladores |
| EP3312184A4 (en) | 2015-06-16 | 2019-02-27 | Jiangsu Hengrui Medicine Co., Ltd. | PIPERIDINE DERIVATIVE AND ITS PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF |
| EP3322706B1 (en) | 2015-07-16 | 2020-11-11 | Array Biopharma, Inc. | Substituted pyrazolo[1,5-a]pyridine compounds as ret kinase inhibitors |
| JP2018536682A (ja) | 2015-12-11 | 2018-12-13 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | Ｅｇｆｒ及び／またはｅｒｂｂ３遮断に耐性のある腫瘍の成長を低減または防止するための方法 |
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| JOP20190077A1 (ar) | 2016-10-10 | 2019-04-09 | Array Biopharma Inc | مركبات بيرازولو [1، 5-a]بيريدين بها استبدال كمثبطات كيناز ret |
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| TWI791053B (zh) | 2017-10-10 | 2023-02-01 | 美商亞雷生物製藥股份有限公司 | 6-(2-羥基-2-甲基丙氧基)-4-(6-(6-((6-甲氧基吡啶-3-基)甲基)-3,6-二氮雜雙環[3.1.1]庚-3-基)吡啶-3-基)吡唑并[1,5-a]吡啶-3-甲腈之結晶形式及其醫藥組合物 |
| TW201938169A (zh) | 2018-01-18 | 2019-10-01 | 美商亞雷生物製藥股份有限公司 | 作為RET激酶抑制劑之經取代吡唑并[3,4-d]嘧啶化合物 |
| WO2019143994A1 (en) | 2018-01-18 | 2019-07-25 | Array Biopharma Inc. | Substituted pyrazolyl[4,3-c]pyridinecompounds as ret kinase inhibitors |
| CN111971286B (zh) | 2018-01-18 | 2023-04-14 | 阿雷生物药品公司 | 作为RET激酶抑制剂的取代的吡咯并[2,3-d]嘧啶化合物 |
| EP3830093A1 (en) | 2018-07-27 | 2021-06-09 | Biotheryx, Inc. | Bifunctional compounds as cdk modulators |
| ES2922314T3 (es) | 2018-09-10 | 2022-09-13 | Array Biopharma Inc | Compuestos heterocíclicos condensados como inhibidores de cinasa RET |
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| WO2021222150A2 (en) | 2020-04-28 | 2021-11-04 | Anwita Biosciences, Inc. | Interleukin-2 polypeptides and fusion proteins thereof, and their pharmaceutical compositions and therapeutic applications |
| CA3182412A1 (en) | 2020-07-06 | 2022-01-13 | Mathew BAGGOTT | Advantageous benzothiophene compositions for mental disorders or enhancement |
| CA3187217A1 (en) | 2020-08-06 | 2022-02-10 | Matthew BAGGOTT | 2-aminoindane compounds for mental disorders or enhancement |
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| WO2008021369A2 (en) * | 2006-08-14 | 2008-02-21 | Chembridge Research Laboratories, Inc. | Tricyclic compounds and its use as tyrosine kinase modulators |
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2009
- 2009-03-18 MX MX2010010272A patent/MX2010010272A/es active IP Right Grant
- 2009-03-18 CN CN200980118256.XA patent/CN102036990B/zh not_active Expired - Fee Related
- 2009-03-18 EP EP09721981.0A patent/EP2262807B1/en not_active Not-in-force
- 2009-03-18 JP JP2011500801A patent/JP5628145B2/ja not_active Expired - Fee Related
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2008021369A2 (en) * | 2006-08-14 | 2008-02-21 | Chembridge Research Laboratories, Inc. | Tricyclic compounds and its use as tyrosine kinase modulators |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9249147B2 (en) | 2008-03-19 | 2016-02-02 | Chembridge Corporation | Tyrosine kinase inhibitors |
| US9273055B2 (en) | 2008-03-19 | 2016-03-01 | Chembridge Corporation | Tyrosine kinase inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102036990B (zh) | 2015-09-30 |
| JP5628145B2 (ja) | 2014-11-19 |
| DK2262807T3 (en) | 2015-11-30 |
| CA2718872C (en) | 2016-09-13 |
| US8815906B2 (en) | 2014-08-26 |
| CA2718872A1 (en) | 2009-09-24 |
| JP2013082744A (ja) | 2013-05-09 |
| MX2010010272A (es) | 2011-05-25 |
| EP2966076A1 (en) | 2016-01-13 |
| WO2009117097A1 (en) | 2009-09-24 |
| EP2262807B1 (en) | 2015-08-12 |
| EP2262807A1 (en) | 2010-12-22 |
| JP2011515397A (ja) | 2011-05-19 |
| CN102036990A (zh) | 2011-04-27 |
| AU2009226153A1 (en) | 2009-09-24 |
| US20130053376A1 (en) | 2013-02-28 |
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| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |