AU2009216672A1 - Copper organocomplexes, use thereof as antitumor means and for protecting healthy tissue from ionizing radiation - Google Patents
Copper organocomplexes, use thereof as antitumor means and for protecting healthy tissue from ionizing radiation Download PDFInfo
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- AU2009216672A1 AU2009216672A1 AU2009216672A AU2009216672A AU2009216672A1 AU 2009216672 A1 AU2009216672 A1 AU 2009216672A1 AU 2009216672 A AU2009216672 A AU 2009216672A AU 2009216672 A AU2009216672 A AU 2009216672A AU 2009216672 A1 AU2009216672 A1 AU 2009216672A1
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- Prior art keywords
- copper
- complex
- tumor
- sarcolysine
- cells
- Prior art date
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- 229960002514 melphalan hydrochloride Drugs 0.000 description 1
- 230000028161 membrane depolarization Effects 0.000 description 1
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- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
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- 238000013421 nuclear magnetic resonance imaging Methods 0.000 description 1
- 238000000655 nuclear magnetic resonance spectrum Methods 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 229930191479 oligomycin Natural products 0.000 description 1
- MNULEGDCPYONBU-AWJDAWNUSA-N oligomycin A Polymers O([C@H]1CC[C@H](/C=C/C=C/C[C@@H](C)[C@H](O)[C@@](C)(O)C(=O)[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)/C=C/C(=O)O[C@@H]([C@@H]2C)[C@@H]1C)CC)[C@@]12CC[C@H](C)[C@H](C[C@@H](C)O)O1 MNULEGDCPYONBU-AWJDAWNUSA-N 0.000 description 1
- 238000011275 oncology therapy Methods 0.000 description 1
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- 229940124531 pharmaceutical excipient Drugs 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 238000000053 physical method Methods 0.000 description 1
- 150000003057 platinum Chemical class 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
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- 238000011127 radiochemotherapy Methods 0.000 description 1
- 230000004223 radioprotective effect Effects 0.000 description 1
- 230000000637 radiosensitizating effect Effects 0.000 description 1
- 230000026267 regulation of growth Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000000246 remedial effect Effects 0.000 description 1
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- 239000008159 sesame oil Substances 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
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- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/005—Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08151840A EP2130832A1 (de) | 2008-02-22 | 2008-02-22 | Kupfer-Organokomplexe, deren Verwendung als Antitumormittel und zum Schutz gesunden Gewebes vor ionisierender Strahlung |
| EP08151840.9 | 2008-02-22 | ||
| PCT/EP2009/052073 WO2009103807A1 (de) | 2008-02-22 | 2009-02-20 | Kupfer-organokomplexe, deren verwendung als antitumormittel und zum schutz gesunden gewebes vor ionisierender strahlung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2009216672A1 true AU2009216672A1 (en) | 2009-08-27 |
Family
ID=39719180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2009216672A Abandoned AU2009216672A1 (en) | 2008-02-22 | 2009-02-20 | Copper organocomplexes, use thereof as antitumor means and for protecting healthy tissue from ionizing radiation |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20110077230A1 (de) |
| EP (2) | EP2130832A1 (de) |
| JP (1) | JP2011512387A (de) |
| CN (1) | CN102007134A (de) |
| AU (1) | AU2009216672A1 (de) |
| BR (1) | BRPI0906011A2 (de) |
| CA (1) | CA2716288A1 (de) |
| RU (1) | RU2010139607A (de) |
| WO (1) | WO2009103807A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104628619A (zh) * | 2015-02-02 | 2015-05-20 | 东力（南通）化工有限公司 | 一种细胞生长抑制剂抗癌药雷阿卡啶及相关衍生物的制备方法 |
| CN113740282A (zh) * | 2021-08-19 | 2021-12-03 | 广东有机宝生物科技股份有限公司 | 一种铜元素含量的测试方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1401425B1 (de) | 2001-07-03 | 2006-08-16 | Valeriy Prof. Dr. Tatarsky | Metallorganisches antitumormittel |
-
2008
- 2008-02-22 EP EP08151840A patent/EP2130832A1/de not_active Ceased
-
2009
- 2009-02-20 US US12/918,131 patent/US20110077230A1/en not_active Abandoned
- 2009-02-20 WO PCT/EP2009/052073 patent/WO2009103807A1/de active Application Filing
- 2009-02-20 CA CA2716288A patent/CA2716288A1/en not_active Abandoned
- 2009-02-20 CN CN2009801139362A patent/CN102007134A/zh active Pending
- 2009-02-20 AU AU2009216672A patent/AU2009216672A1/en not_active Abandoned
- 2009-02-20 RU RU2010139607/04A patent/RU2010139607A/ru not_active Application Discontinuation
- 2009-02-20 EP EP09712104A patent/EP2257558A1/de not_active Withdrawn
- 2009-02-20 BR BRPI0906011-1A patent/BRPI0906011A2/pt not_active IP Right Cessation
- 2009-02-20 JP JP2010547190A patent/JP2011512387A/ja not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2716288A1 (en) | 2009-08-27 |
| EP2257558A1 (de) | 2010-12-08 |
| JP2011512387A (ja) | 2011-04-21 |
| CN102007134A (zh) | 2011-04-06 |
| US20110077230A1 (en) | 2011-03-31 |
| RU2010139607A (ru) | 2012-03-27 |
| WO2009103807A1 (de) | 2009-08-27 |
| EP2130832A1 (de) | 2009-12-09 |
| WO2009103807A8 (de) | 2010-09-16 |
| BRPI0906011A2 (pt) | 2015-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC1 | Assignment before grant (sect. 113) |
Owner name: CHARITE - UNIVERSITATSMEDIZIN BERLIN; IPAL GESELLS Free format text: FORMER APPLICANT(S): CHARITE - UNIVERSITATSMEDIZIN BERLIN; TATARSKIY, VALERIY |
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| MK1 | Application lapsed section 142(2)(a) - no request for examination in relevant period |