AU2008314689A1 - Method for purifying an Fc-containing protein - Google Patents

Method for purifying an Fc-containing protein Download PDF

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Publication number
AU2008314689A1
AU2008314689A1 AU2008314689A AU2008314689A AU2008314689A1 AU 2008314689 A1 AU2008314689 A1 AU 2008314689A1 AU 2008314689 A AU2008314689 A AU 2008314689A AU 2008314689 A AU2008314689 A AU 2008314689A AU 2008314689 A1 AU2008314689 A1 AU 2008314689A1
Authority
AU
Australia
Prior art keywords
protein
resin
containing protein
blue
free
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2008314689A
Other languages
English (en)
Inventor
Alex Eon-Duval
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Serono SA
Original Assignee
Merck Serono SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Serono SA filed Critical Merck Serono SA
Publication of AU2008314689A1 publication Critical patent/AU2008314689A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
AU2008314689A 2007-10-22 2008-10-21 Method for purifying an Fc-containing protein Abandoned AU2008314689A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP07118983.1 2007-10-22
EP07118983 2007-10-22
US722307P 2007-12-11 2007-12-11
US61/007,223 2007-12-11
PCT/EP2008/064210 WO2009053360A1 (en) 2007-10-22 2008-10-21 Method for purifying an fc-containing protein

Publications (1)

Publication Number Publication Date
AU2008314689A1 true AU2008314689A1 (en) 2009-04-30

Family

ID=38961834

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008314689A Abandoned AU2008314689A1 (en) 2007-10-22 2008-10-21 Method for purifying an Fc-containing protein

Country Status (7)

Country Link
US (1) US20100256337A1 (enExample)
EP (1) EP2203465A1 (enExample)
JP (1) JP2011500757A (enExample)
AU (1) AU2008314689A1 (enExample)
CA (1) CA2701221A1 (enExample)
IL (1) IL204949A0 (enExample)
WO (1) WO2009053360A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080219952A1 (en) * 2005-08-26 2008-09-11 Ares Trading S.A. Process For the Preparation of Glycosylated Interferon Beta
CA2702448A1 (en) * 2007-10-22 2009-04-30 Merck Serono S.A. Method for purifying fc-fusion proteins
CA2752393C (en) 2009-03-05 2020-01-14 Biogen Ma Inc. Purification of immunoglobulins
CN104870019A (zh) 2012-11-27 2015-08-26 阿特根公司 用于稳定蛋白质和Fc结构域融合的融合蛋白的组合物
EP2918641A1 (en) * 2014-03-13 2015-09-16 Basf Se Method for purification of antibodies, antibody fragments or engineered variants thereof using specific anthraquinone dye-ligand structures
SG11201605954SA (en) * 2014-02-04 2016-08-30 Basf Se Method for purification of antibodies, antibody fragments or engineered variants thereof using specific anthraquinone dye-ligand structures
WO2015189832A1 (en) * 2014-06-13 2015-12-17 Lupin Limited Process for the purification of tnfr:fc fusion protein
US9821059B2 (en) 2014-10-17 2017-11-21 Alteogen Inc. Composition for stabilizing protein and pharmaceutical formulation comprising the same
EP3694870A1 (en) 2017-10-10 2020-08-19 Alpine Immune Sciences, Inc. Ctla-4 variant immunomodulatory proteins and uses thereof
US12202882B2 (en) 2020-05-08 2025-01-21 Alpine Immune Sciences, Inc. APRIL and BAFF inhibitory immunomodulatory proteins and methods of use thereof
CN120904317A (zh) * 2025-09-28 2025-11-07 中国医学科学院输血研究所 一种两步亲和层析法制备犬用免疫球蛋白的方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4966843A (en) * 1982-11-01 1990-10-30 Cetus Corporation Expression of interferon genes in Chinese hamster ovary cells
DE122010000006I2 (de) * 1989-02-21 2012-06-21 Univ Washington Modifizierte formen von fortpflanzungshormonen.
US5338835A (en) * 1989-02-21 1994-08-16 Washington University CTP-extended form of FSH
GEP20002142B (en) 1991-01-18 2000-06-25 Amgen Inc Method for Treatment and Prevention of TNF Mediated Diseases
US5508261A (en) * 1991-06-18 1996-04-16 University Of Medicine & Dentistry Of New Jersey Analogs of glycoprotein hormones having altered receptor binding specificity and activity and methods for preparing and using same
SE9201073D0 (sv) * 1992-04-03 1992-04-03 Kabi Pharmacia Ab Protein formulation
US6162905A (en) * 1996-11-07 2000-12-19 Ibsa Institut Biochimique S.A. FSH and LH separation and purification process
US5883073A (en) * 1997-04-03 1999-03-16 Washington University Single-chain double-alpha peptide
US5990288A (en) * 1997-10-21 1999-11-23 Vitro Diagnostics, Inc. Method for purifying FSH
US7431921B2 (en) * 1999-08-27 2008-10-07 Maxygen Aps Interferon beta-like molecules
HRP20020651B1 (en) * 2000-02-22 2011-01-31 Laboratoires Serono Sa Purified lh
US6926898B2 (en) * 2000-04-12 2005-08-09 Human Genome Sciences, Inc. Albumin fusion proteins
US20030017550A1 (en) * 2001-01-22 2003-01-23 Pang Danny Zhong Der DNA sequences encoding fusion proteins comprising IFN-beta and TM-alpha1
US7226903B2 (en) * 2001-10-10 2007-06-05 Neose Technologies, Inc. Interferon beta: remodeling and glycoconjugation of interferon beta
CA2841097A1 (en) * 2001-12-21 2003-07-24 Human Genome Sciences, Inc. Albumin and g-csf fusion proteins
TWI353991B (en) * 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
ATE446314T1 (de) * 2003-12-22 2009-11-15 Ares Trading Sa Methode zur reinigung von fsh
EP1809663B1 (en) * 2004-11-09 2008-09-17 Ares Trading S.A. Method for purifying fsh
US20080219952A1 (en) * 2005-08-26 2008-09-11 Ares Trading S.A. Process For the Preparation of Glycosylated Interferon Beta
JP5199112B2 (ja) * 2005-12-09 2013-05-15 アレス トレーディング ソシエテ アノニム Fsh又はfsh変異体を精製するための方法
ZA200805194B (en) * 2006-01-17 2009-10-28 Serono Lab Novel FSH glycosylation variant D3N
CA2702448A1 (en) * 2007-10-22 2009-04-30 Merck Serono S.A. Method for purifying fc-fusion proteins

Also Published As

Publication number Publication date
WO2009053360A1 (en) 2009-04-30
EP2203465A1 (en) 2010-07-07
JP2011500757A (ja) 2011-01-06
US20100256337A1 (en) 2010-10-07
CA2701221A1 (en) 2009-04-30
IL204949A0 (en) 2010-11-30

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period