AU2008302746B2 - 1-(4-(benzylbenzamid0) -benzyl) azetidine-3-carboxylic acid derivatives and related compounds as SlP receptor modulators for the treatment of immune disorders - Google Patents

1-(4-(benzylbenzamid0) -benzyl) azetidine-3-carboxylic acid derivatives and related compounds as SlP receptor modulators for the treatment of immune disorders Download PDF

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Publication number
AU2008302746B2
AU2008302746B2 AU2008302746A AU2008302746A AU2008302746B2 AU 2008302746 B2 AU2008302746 B2 AU 2008302746B2 AU 2008302746 A AU2008302746 A AU 2008302746A AU 2008302746 A AU2008302746 A AU 2008302746A AU 2008302746 B2 AU2008302746 B2 AU 2008302746B2
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alk
haloalk
compounds
halogen
hydrogen
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AU2008302746A1 (en
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Roland Burli
Victor Cee
Brian Lanman
Susana C. Neira
Xiang Yu
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Amgen Inc
Epix Pharmaceuticals Inc
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Amgen Inc
Epix Pharmaceuticals Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings

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  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
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  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2008302746A 2007-09-20 2008-09-19 1-(4-(benzylbenzamid0) -benzyl) azetidine-3-carboxylic acid derivatives and related compounds as SlP receptor modulators for the treatment of immune disorders Ceased AU2008302746B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99481207P 2007-09-20 2007-09-20
US60/994,812 2007-09-20
PCT/US2008/010887 WO2009038759A2 (en) 2007-09-20 2008-09-19 1-(4-(benzylbenzamid0) -benzyl) azetidine-3-carboxylic acid derivatives and related compounds as slp receptor modulators for the treatment of immune disorders

Publications (2)

Publication Number Publication Date
AU2008302746A1 AU2008302746A1 (en) 2009-03-26
AU2008302746B2 true AU2008302746B2 (en) 2014-07-03

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AU2008302746A Ceased AU2008302746B2 (en) 2007-09-20 2008-09-19 1-(4-(benzylbenzamid0) -benzyl) azetidine-3-carboxylic acid derivatives and related compounds as SlP receptor modulators for the treatment of immune disorders

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US (2) US8080542B2 (OSRAM)
EP (1) EP2188252B1 (OSRAM)
JP (1) JP2010540438A (OSRAM)
AT (1) ATE505454T1 (OSRAM)
AU (1) AU2008302746B2 (OSRAM)
CA (1) CA2699417A1 (OSRAM)
DE (1) DE602008006209D1 (OSRAM)
ES (1) ES2360929T3 (OSRAM)
MX (1) MX2010002885A (OSRAM)
WO (1) WO2009038759A2 (OSRAM)

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MD3790877T2 (ro) 2018-05-11 2023-08-31 Incyte Corp Derivați de tetrahidro-imidazo[4,5-c]piridină în calitate de imunomodulatori PD-L1
JP7665593B2 (ja) 2019-08-09 2025-04-21 インサイト・コーポレイション Ｐｄ－１／ｐｄ－ｌ１阻害剤の塩
AR120109A1 (es) 2019-09-30 2022-02-02 Incyte Corp Compuestos de pirido[3,2-d]pirimidina como inmunomoduladores
PE20230407A1 (es) 2019-11-11 2023-03-07 Incyte Corp Sales y formas cristalinas de un inhibidor de pd-1/pd-l1
TW202233616A (zh) 2020-11-06 2022-09-01 美商英塞特公司 用於製備ｐｄ－１／ｐｄ－ｌ１抑制劑以及其鹽及結晶形式之方法
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EP2188252B1 (en) 2011-04-13
ES2360929T3 (es) 2011-06-10
AU2008302746A1 (en) 2009-03-26
DE602008006209D1 (de) 2011-05-26
US20090082331A1 (en) 2009-03-26
JP2010540438A (ja) 2010-12-24
ATE505454T1 (de) 2011-04-15
CA2699417A1 (en) 2009-03-26
US20120088749A1 (en) 2012-04-12
WO2009038759A3 (en) 2009-07-23
MX2010002885A (es) 2010-04-01

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