AU2008266885A1 - Treatment of diseases and disorders using self-renewing colony forming cells cultured and expanded in vitro - Google Patents

Treatment of diseases and disorders using self-renewing colony forming cells cultured and expanded in vitro Download PDF

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Publication number
AU2008266885A1
AU2008266885A1 AU2008266885A AU2008266885A AU2008266885A1 AU 2008266885 A1 AU2008266885 A1 AU 2008266885A1 AU 2008266885 A AU2008266885 A AU 2008266885A AU 2008266885 A AU2008266885 A AU 2008266885A AU 2008266885 A1 AU2008266885 A1 AU 2008266885A1
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Australia
Prior art keywords
cells
tissue
bone marrow
disease
damage
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Abandoned
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AU2008266885A
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English (en)
Inventor
Richard S. Gore
Baron Heimbach
Gene Kopen
Vanessa Ragaglia
Joseph Wagner
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Garnet BioTherapeutics Inc
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Garnet BioTherapeutics Inc
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Publication date
Application filed by Garnet BioTherapeutics Inc filed Critical Garnet BioTherapeutics Inc
Publication of AU2008266885A1 publication Critical patent/AU2008266885A1/en
Priority to AU2013202319A priority Critical patent/AU2013202319A1/en
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0669Bone marrow stromal cells; Whole bone marrow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1722Plasma globulins, lactoglobulins
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
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    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
AU2008266885A 2007-06-15 2008-06-16 Treatment of diseases and disorders using self-renewing colony forming cells cultured and expanded in vitro Abandoned AU2008266885A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2013202319A AU2013202319A1 (en) 2007-06-15 2013-04-03 Treatment of diseases and disorders using self-renewing colony forming cells cultured and expanded in vitro

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US92915207P 2007-06-15 2007-06-15
US92915107P 2007-06-15 2007-06-15
US60/929,151 2007-06-15
US60/929,152 2007-06-15
US95520407P 2007-08-10 2007-08-10
US60/955,204 2007-08-10
US99609307P 2007-11-01 2007-11-01
US60/996,093 2007-11-01
PCT/US2008/007488 WO2008156728A1 (en) 2007-06-15 2008-06-16 Treatment of diseases and disorders using self-renewing colony forming cells cultured and expanded in vitro

Related Child Applications (1)

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AU2013202319A Division AU2013202319A1 (en) 2007-06-15 2013-04-03 Treatment of diseases and disorders using self-renewing colony forming cells cultured and expanded in vitro

Publications (1)

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AU2008266885A1 true AU2008266885A1 (en) 2008-12-24

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AU2008266885A Abandoned AU2008266885A1 (en) 2007-06-15 2008-06-16 Treatment of diseases and disorders using self-renewing colony forming cells cultured and expanded in vitro

Country Status (14)

Country Link
US (5) US8354370B2 (enExample)
EP (1) EP2171043B1 (enExample)
JP (1) JP2010529987A (enExample)
KR (1) KR20100035648A (enExample)
CN (1) CN101835891A (enExample)
AP (1) AP2010005103A0 (enExample)
AU (1) AU2008266885A1 (enExample)
CA (1) CA2690143A1 (enExample)
CO (1) CO6251330A2 (enExample)
EA (1) EA201070022A1 (enExample)
IL (1) IL202445A0 (enExample)
MX (1) MX2009013672A (enExample)
NZ (1) NZ582616A (enExample)
WO (1) WO2008156728A1 (enExample)

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US11253629B2 (en) 2016-04-22 2022-02-22 Vivex Biologics Group, Inc. Bone gel sheet composition and method of manufacture
US11253630B2 (en) 2016-04-22 2022-02-22 Vivex Biologics Group, Inc. Malleable demineralized bone composition and method of manufacture
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US20210088505A1 (en) * 2017-04-07 2021-03-25 La Jolla Institute For Allergy And Immunology Unipotent Neutrophil Progenitor Cells, Methods of Preparation, and Uses Thereof
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CN111394306B (zh) * 2020-04-15 2023-08-01 深圳市旷逸生物科技有限公司 一种提高脐带间充质干细胞的体外扩增速率的培养方法
CN114591910B (zh) * 2022-03-28 2023-11-21 重庆市铂而斐细胞生物技术有限公司 一种利用低氧三维环境培养的间充质干细胞富集脐血造血干细胞的方法

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US8354370B2 (en) 2013-01-15
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US20090053183A1 (en) 2009-02-26
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