AU2008263897A1 - [1,10]-phenanthroline derivatives for the treatment of neurodegenerative or haematological diseases - Google Patents

[1,10]-phenanthroline derivatives for the treatment of neurodegenerative or haematological diseases Download PDF

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Publication number
AU2008263897A1
AU2008263897A1 AU2008263897A AU2008263897A AU2008263897A1 AU 2008263897 A1 AU2008263897 A1 AU 2008263897A1 AU 2008263897 A AU2008263897 A AU 2008263897A AU 2008263897 A AU2008263897 A AU 2008263897A AU 2008263897 A1 AU2008263897 A1 AU 2008263897A1
Authority
AU
Australia
Prior art keywords
phenanthroline
compound
carbaldehyde
alkyl
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2008263897A
Other languages
English (en)
Inventor
Mercedes Alonso Cascon
Ana Castro Morera
Esther Garcia Palomero
Ana Martinez Gil
Miguel Medina Padilla
Laura Rubio Arrieta
Jorge Sanchez-Quesada
Paola Usan Egea
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Noscira SA
Original Assignee
Noscira SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Noscira SA filed Critical Noscira SA
Publication of AU2008263897A1 publication Critical patent/AU2008263897A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2008263897A 2007-06-11 2008-06-11 [1,10]-phenanthroline derivatives for the treatment of neurodegenerative or haematological diseases Abandoned AU2008263897A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07380167.2 2007-06-11
EP07380167A EP2002863A1 (en) 2007-06-11 2007-06-11 [1,10]-phenanthroline derivatives for the treatment of neurodegenerative or haematological diseases
PCT/EP2008/057319 WO2008152068A2 (en) 2007-06-11 2008-06-11 [1,10]-phenanthroline derivatives for the treatment of neurodegenerative or haematological diseases

Publications (1)

Publication Number Publication Date
AU2008263897A1 true AU2008263897A1 (en) 2008-12-18

Family

ID=38596362

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008263897A Abandoned AU2008263897A1 (en) 2007-06-11 2008-06-11 [1,10]-phenanthroline derivatives for the treatment of neurodegenerative or haematological diseases

Country Status (13)

Country Link
US (2) US8592446B2 (cg-RX-API-DMAC7.html)
EP (2) EP2002863A1 (cg-RX-API-DMAC7.html)
JP (1) JP2010529167A (cg-RX-API-DMAC7.html)
CN (1) CN101801461A (cg-RX-API-DMAC7.html)
AR (1) AR066956A1 (cg-RX-API-DMAC7.html)
AU (1) AU2008263897A1 (cg-RX-API-DMAC7.html)
CA (1) CA2690455A1 (cg-RX-API-DMAC7.html)
CL (1) CL2008001719A1 (cg-RX-API-DMAC7.html)
MX (1) MX2009013482A (cg-RX-API-DMAC7.html)
RU (1) RU2009148821A (cg-RX-API-DMAC7.html)
TW (1) TW200914016A (cg-RX-API-DMAC7.html)
UY (1) UY31143A1 (cg-RX-API-DMAC7.html)
WO (1) WO2008152068A2 (cg-RX-API-DMAC7.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6000272B2 (ja) 2010-12-01 2016-09-28 中国石油化工股▲ふん▼有限公司 窒素のオルソ位にアシル基が置換した窒素含有複素環式化合物およびそのアミナール鉄（ｉｉ）錯体の製造方法
CN102532201B (zh) * 2010-12-01 2014-11-05 中国石油化工股份有限公司 甲酰基取代的1,10-菲咯啉配合物的制备及由此制备的配合物作为催化剂的应用
CN102558241B (zh) * 2010-12-01 2014-11-26 中国石油化工股份有限公司 丙酰基取代的1,10-菲咯啉配合物的制备及由此制备的配合物作为催化剂的应用
CN106083713B (zh) * 2016-07-15 2019-07-26 浙江工业大学 一种喹(喔)啉-2-甲醛类化合物的化学合成方法
WO2021176428A1 (en) * 2020-03-06 2021-09-10 Jawaharlal Nehru Centre For Advanced Scientific Research Phenanthroline, carbazole and flavylium based cyanines and compositions and methods of making and using the same
CA3232921A1 (en) * 2021-09-28 2023-04-06 Zevra Denmark A/S Oximes and their use in treatment of gba-related diseases
CN117983303B (zh) * 2022-11-01 2026-04-07 万华化学集团股份有限公司 一种金属配合物及其配体，催化剂组合物及香茅醇的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL76345B1 (cg-RX-API-DMAC7.html) * 1971-02-13 1975-06-30

Also Published As

Publication number Publication date
CN101801461A (zh) 2010-08-11
JP2010529167A (ja) 2010-08-26
WO2008152068A2 (en) 2008-12-18
CL2008001719A1 (es) 2009-01-02
MX2009013482A (es) 2010-01-27
US20140011835A1 (en) 2014-01-09
UY31143A1 (es) 2009-01-30
US20100240692A1 (en) 2010-09-23
CA2690455A1 (en) 2008-12-18
AR066956A1 (es) 2009-09-23
WO2008152068A3 (en) 2009-05-07
RU2009148821A (ru) 2011-07-20
EP2170464A2 (en) 2010-04-07
EP2002863A1 (en) 2008-12-17
TW200914016A (en) 2009-04-01
US8592446B2 (en) 2013-11-26

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Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application