AU2008244648A1 - Blocking the migration or metastasis of cancer cells by affecting adhesion proteins and the uses of new compounds thereof - Google Patents

Blocking the migration or metastasis of cancer cells by affecting adhesion proteins and the uses of new compounds thereof Download PDF

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Publication number
AU2008244648A1
AU2008244648A1 AU2008244648A AU2008244648A AU2008244648A1 AU 2008244648 A1 AU2008244648 A1 AU 2008244648A1 AU 2008244648 A AU2008244648 A AU 2008244648A AU 2008244648 A AU2008244648 A AU 2008244648A AU 2008244648 A1 AU2008244648 A1 AU 2008244648A1
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Prior art keywords
angiopoietin
cancer
benzoyl
compound
angeloyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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AU2008244648A
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English (en)
Inventor
Pui-Kwong Chan
May Sung Mak
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Pacific Arrow Ltd
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Pacific Arrow Ltd
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Filing date
Publication date
Priority claimed from US11/683,198 external-priority patent/US8614197B2/en
Priority claimed from PCT/US2007/077273 external-priority patent/WO2008028060A2/fr
Application filed by Pacific Arrow Ltd filed Critical Pacific Arrow Ltd
Publication of AU2008244648A1 publication Critical patent/AU2008244648A1/en
Abandoned legal-status Critical Current

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    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Pregnancy & Childbirth (AREA)
AU2008244648A 2007-02-16 2008-02-15 Blocking the migration or metastasis of cancer cells by affecting adhesion proteins and the uses of new compounds thereof Abandoned AU2008244648A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US89038007P 2007-02-16 2007-02-16
US60/890,380 2007-02-16
US11/683,198 2007-03-07
US11/683,198 US8614197B2 (en) 2003-10-09 2007-03-07 Anti-tumor compounds with angeloyl groups
US94770507P 2007-07-03 2007-07-03
US60/947,705 2007-07-03
PCT/US2007/077273 WO2008028060A2 (fr) 2006-09-01 2007-08-30 Composés antitumoraux servant à inhiber le développement du cancer
AUPCT/US2007/077273 2007-08-30
PCT/US2008/002086 WO2008133766A1 (fr) 2007-02-16 2008-02-15 Blocage de la migration ou de la metastase des cellules cancereuses par la modification de proteines d'adhesion et utilisations de nouveaux composes associes

Publications (1)

Publication Number Publication Date
AU2008244648A1 true AU2008244648A1 (en) 2008-11-06

Family

ID=39925959

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008244648A Abandoned AU2008244648A1 (en) 2007-02-16 2008-02-15 Blocking the migration or metastasis of cancer cells by affecting adhesion proteins and the uses of new compounds thereof

Country Status (7)

Country Link
EP (1) EP2121715A4 (fr)
JP (1) JP2010519219A (fr)
CN (1) CN101772511A (fr)
AU (1) AU2008244648A1 (fr)
CA (1) CA2676791A1 (fr)
SG (1) SG178795A1 (fr)
WO (1) WO2008133766A1 (fr)

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US7727561B2 (en) 2001-08-31 2010-06-01 Pacific Arrow Limited Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
US7524824B2 (en) 2003-09-04 2009-04-28 Pacific Arrow Limited Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
US8614197B2 (en) 2003-10-09 2013-12-24 Pacific Arrow Limited Anti-tumor compounds with angeloyl groups
US7514412B2 (en) 2003-10-09 2009-04-07 Pacific Arrow Limited Anticancer biangeloyl saponins
US7488753B2 (en) 2003-10-09 2009-02-10 Pacific Arrow Limited Composition comprising triterpene saponins and compounds with angeloyl functional group, methods for preparing same and uses thereof
US8586719B2 (en) 2005-04-27 2013-11-19 Pacific Arrow Limited Triterpenes for modulating gene expression and cell membrane, and as antiprotozoal agents
US20120277308A1 (en) 2010-07-16 2012-11-01 Pacific Arrow Limited compounds for treating cancer and other diseases
CN115197293A (zh) * 2010-07-16 2022-10-18 太平洋艾瑞有限公司 可治疗癌症和其它疾病的新化合物
KR101398079B1 (ko) 2011-10-10 2014-05-27 재단법인 의약바이오컨버젼스연구단 글리실-티알엔에이 합성효소 및 캐드헤린을 이용한 암 예방 또는 치료제의 스크리닝 방법
KR101403019B1 (ko) 2013-02-25 2014-06-03 서울대학교산학협력단 폐암 진단용 마커
EP3272880B1 (fr) 2013-03-15 2020-11-25 Fundació Institut de Recerca Biomèdica (IRB Barcelona) Procédé pour le diagnostic, le pronostic et le traitement de cancer métastatique
CN103235141A (zh) * 2013-04-27 2013-08-07 上海交通大学医学院附属新华医院 Atf3用于预测膀胱癌转移和判断预后的应用
JP6339814B2 (ja) * 2014-02-05 2018-06-06 株式会社島津製作所 がん転移マーカー及びその分析方法
CN104502603B (zh) * 2014-12-03 2016-04-06 上海交通大学医学院附属上海儿童医学中心 Myo1d作为诊断动脉导管闭合或开放的标志物
CA2967224C (fr) 2014-12-11 2023-08-22 Inbiomotion S.L. Elements de liaison pour c-maf humain
CN105061545B (zh) * 2015-08-17 2018-01-30 中国人民解放军第二一〇医院 文冠果中三萜皂苷类化合物及其制备方法和应用
US10167293B2 (en) * 2016-05-26 2019-01-01 Bayer Pharma Aktiengesellschaft [8-(phenylsulfonyl)-3,8-diazabicyclo[3.2.1]oct-3-yl](1H-1,2,3-triazol-4-yl)methanones
CN106947821B (zh) * 2017-04-11 2020-06-30 成都望路医药技术有限公司 用于诊治结肠腺癌的生物标志物
CN108410986B (zh) * 2018-02-26 2021-06-22 中国人民解放军总医院 Cdh6促进骨肉瘤生长和转移
CN110272997B (zh) * 2018-03-14 2023-04-28 华中科技大学同济医学院附属同济医院 一种C/EBPβ基因或者蛋白的用途
KR102128331B1 (ko) * 2018-04-30 2020-06-30 인하대학교 산학협력단 Cdh13 또는 이를 코딩하는 유전자의 발현을 억제하는 제제를 포함하는, 방사선 치료로 인하여 노화된 혈관내피세포로 전이가 발생하는 암 전이 억제용 조성물
CN109970839B (zh) * 2019-04-16 2022-03-01 沈阳药科大学 三萜皂苷类化合物及其制备方法和医药用途
CN110672848A (zh) * 2019-10-25 2020-01-10 四川大学华西医院 Apeh自身抗体检测试剂在制备肺癌筛查试剂盒中的用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6616943B2 (en) * 2001-08-31 2003-09-09 Fountain Silver Limited Composition comprising Wenguanguo extracts and methods for preparing same
CN101242850B (zh) * 2003-10-09 2013-03-20 太平洋艾瑞有限公司 文冠果的提取物和从提取物分离出的化合物的组成，功能和应用，以及它们的制备方法
US7488753B2 (en) * 2003-10-09 2009-02-10 Pacific Arrow Limited Composition comprising triterpene saponins and compounds with angeloyl functional group, methods for preparing same and uses thereof
TWI454269B (zh) * 2003-12-23 2014-10-01 Pacific Arrow Ltd 由文冠果（ｘａｎｔｈｏｃｅｒａｓ ｓｏｒｂｉｆｏｌｉａ）單離之化合物、其製備方法以及其用途
JP5087400B2 (ja) * 2004-09-07 2012-12-05 パシフィック アロー リミテッド アンゲロイル基を有する抗腫瘍化合物
CN101553497B (zh) * 2006-09-01 2013-03-27 太平洋艾瑞有限公司 能抑止癌细胞生长的抗肿瘤化合物

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