AU2008230724A1 - Modulation of tumor microenvironment - Google Patents

Modulation of tumor microenvironment Download PDF

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Publication number
AU2008230724A1
AU2008230724A1 AU2008230724A AU2008230724A AU2008230724A1 AU 2008230724 A1 AU2008230724 A1 AU 2008230724A1 AU 2008230724 A AU2008230724 A AU 2008230724A AU 2008230724 A AU2008230724 A AU 2008230724A AU 2008230724 A1 AU2008230724 A1 AU 2008230724A1
Authority
AU
Australia
Prior art keywords
cells
antibody
interleukin
atcc deposit
malignant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2008230724A
Other languages
English (en)
Other versions
AU2008230724A8 (en
Inventor
Kandasamy Hariharan
Steffan Ho
Shabnam Tangri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogen Inc
Original Assignee
Biogen Idec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Idec Inc filed Critical Biogen Idec Inc
Publication of AU2008230724A1 publication Critical patent/AU2008230724A1/en
Publication of AU2008230724A8 publication Critical patent/AU2008230724A8/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507Comprising a combination of two or more separate antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2008230724A 2007-03-28 2008-03-28 Modulation of tumor microenvironment Abandoned AU2008230724A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90864507P 2007-03-28 2007-03-28
US60/908,645 2007-03-28
PCT/US2008/058744 WO2008119071A1 (en) 2007-03-28 2008-03-28 Modulation of tumor microenvironment

Publications (2)

Publication Number Publication Date
AU2008230724A1 true AU2008230724A1 (en) 2008-10-02
AU2008230724A8 AU2008230724A8 (en) 2009-11-26

Family

ID=39485176

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008230724A Abandoned AU2008230724A1 (en) 2007-03-28 2008-03-28 Modulation of tumor microenvironment

Country Status (8)

Country Link
US (1) US20100203010A1 (enExample)
EP (1) EP2139923A1 (enExample)
JP (1) JP2010522772A (enExample)
CN (1) CN101679522A (enExample)
AU (1) AU2008230724A1 (enExample)
BR (1) BRPI0809386A2 (enExample)
CA (1) CA2682027A1 (enExample)
WO (1) WO2008119071A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6014799B2 (ja) * 2010-07-20 2016-10-26 Linfops有限会社 解析によるミクロな腫瘍免疫挙動の顕微鏡的把握方法
CN106749662B (zh) * 2011-03-31 2021-06-18 国家医疗保健研究所 抗icos的抗体及其用途
WO2013116686A1 (en) 2012-02-02 2013-08-08 Massachusetts Institute Of Technology Methods and products related to targeted cancer therapy
SG11201510552WA (en) 2012-06-27 2016-01-28 Hasumi Internat Res Foundation Therapy and method for intratumorally introducing cytotoxic t lymphocyte and/or nkt cell with anti-tnf and/or anti-il-10
US9907819B2 (en) 2012-06-27 2018-03-06 Kenichiro Hasumi Therapy and methods of introducing immature dendritic cells and/or cytotoxic T lymphocyte and anti-TNF antibody for treatment of tumors
US9945870B2 (en) 2013-05-17 2018-04-17 The Board Of Trustees Of The Leland Stanford Junior University Methods for determining responsiveness to an anti-CD47 agent
WO2015077532A1 (en) * 2013-11-21 2015-05-28 Hasumi International Research Foundation Therapy and methods of introducing immature dendritic cells and/or cytotoxic t lymphocyte and anti-tnf antibody for treatment of tumors
US10519237B2 (en) 2014-03-12 2019-12-31 Yeda Research And Development Co. Ltd Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
US10618963B2 (en) 2014-03-12 2020-04-14 Yeda Research And Development Co. Ltd Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
ES3040431T3 (en) 2014-03-12 2025-10-31 Yeda Res & Dev Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns
EP4046656A1 (en) * 2014-11-06 2022-08-24 HiberCell, Inc. Beta-glucan methods and compositions that affect the tumor microenvironment
US20160206717A1 (en) * 2015-01-16 2016-07-21 Batu Biologics, Inc. Stimulation of immunity to endothelial cells, endothelial-like cells, and intratumor vascular channels derived from tumor tissue
JP2016155776A (ja) * 2015-02-24 2016-09-01 学校法人兵庫医科大学 抗腫瘍効果増強剤および抗腫瘍剤
MA43163A (fr) 2015-11-02 2018-09-12 Five Prime Therapeutics Inc Polypeptides à domaine extracellulaire cd80 et leur utilisation dans le traitement du cancer
JP2020517913A (ja) 2017-04-28 2020-06-18 ファイブ プライム セラピューティクス, インコーポレイテッド Cd80細胞外ドメインポリペプチドによる治療方法
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7175847B1 (en) * 1995-06-07 2007-02-13 Biogen Idec Inc. Treating intestinal inflammation with anti-CD80 antibodies that do not inhibit CD80 binding to CTLA-4
WO1996040260A2 (en) * 1995-06-07 1996-12-19 Innogenetics N.V. Immunotoxins specific for cd80 and cd86 expressing cells
AU2001264747A1 (en) * 2000-05-22 2001-12-03 Idec Pharmaceuticals Corporation Identification of unique binding interactions between certain antibodies and thehuman b7.1 and b7.2 co-stimulatory antigens
US20070065436A1 (en) * 2001-01-31 2007-03-22 Biogen Idec Inc. Anti-cd80 antibody having adcc activity for adcc mediated killing of b cell lymphoma cells alone or in combination with other therapies

Also Published As

Publication number Publication date
CN101679522A (zh) 2010-03-24
AU2008230724A8 (en) 2009-11-26
BRPI0809386A2 (pt) 2014-09-09
CA2682027A1 (en) 2008-10-02
US20100203010A1 (en) 2010-08-12
WO2008119071A1 (en) 2008-10-02
JP2010522772A (ja) 2010-07-08
EP2139923A1 (en) 2010-01-06

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Legal Events

Date Code Title Description
TH Corrigenda

Free format text: IN VOL 23, NO 44, PAGE(S) 10930 UNDER THE HEADING PCT APPLICATIONS THAT HAVE ENTERED THE NATIONAL PHASE - NAME INDEX UNDER THE NAME BIOGENT IDEC INC., APPLICATION NO. 2008230724, UNDER INID (71) CORRECT THE APPLICANT TO READ BIOGEN IDEC INC.

MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period