AU2007332855B2 - Monoclonal antibodies against ANGPTL3 - Google Patents
Monoclonal antibodies against ANGPTL3 Download PDFInfo
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- AU2007332855B2 AU2007332855B2 AU2007332855A AU2007332855A AU2007332855B2 AU 2007332855 B2 AU2007332855 B2 AU 2007332855B2 AU 2007332855 A AU2007332855 A AU 2007332855A AU 2007332855 A AU2007332855 A AU 2007332855A AU 2007332855 B2 AU2007332855 B2 AU 2007332855B2
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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| PCT/US2007/025080 WO2008073300A2 (en) | 2006-12-08 | 2007-12-06 | Monoclonal antibodies against angptl3 |
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| US9388413B2 (en) | 2008-10-08 | 2016-07-12 | Trustees Of Dartmouth College | Method for selectively inhibiting ACAT1 in the treatment of neurodegenerative diseases |
| US8802646B2 (en) | 2008-10-08 | 2014-08-12 | Trustees Of Dartmouth College | Method for selectively inhibiting the activity of ACAT1 in the treatment of alzheimer's disease |
| US9149492B2 (en) | 2008-10-08 | 2015-10-06 | Trustees Of Dartmouth College | Method for selectively inhibiting ACAT1 in the treatment of alzheimer's disease |
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| AU2007332855A1 (en) | 2008-06-19 |
| PT2121751T (pt) | 2017-04-18 |
| PL2121751T3 (pl) | 2017-07-31 |
| DK2121751T3 (en) | 2017-04-24 |
| CN101855241B (zh) | 2013-11-06 |
| US20080177045A1 (en) | 2008-07-24 |
| JP2010512320A (ja) | 2010-04-22 |
| BRPI0720218A2 (pt) | 2013-12-24 |
| WO2008073300A2 (en) | 2008-06-19 |
| KR101503937B1 (ko) | 2015-03-18 |
| EP2121751B1 (en) | 2017-01-25 |
| WO2008073300A3 (en) | 2009-12-23 |
| ES2618830T3 (es) | 2017-06-22 |
| US7935796B2 (en) | 2011-05-03 |
| EA019661B1 (ru) | 2014-05-30 |
| NO20092215L (no) | 2009-08-19 |
| KR20090088925A (ko) | 2009-08-20 |
| IL199216A (en) | 2016-02-29 |
| ZA200904022B (en) | 2010-08-25 |
| CA2672049C (en) | 2016-05-10 |
| EP2121751A2 (en) | 2009-11-25 |
| JP5484063B2 (ja) | 2014-05-07 |
| US8742075B2 (en) | 2014-06-03 |
| US20110243948A1 (en) | 2011-10-06 |
| EA200970556A1 (ru) | 2010-04-30 |
| AR064205A1 (es) | 2009-03-18 |
| TW200846364A (en) | 2008-12-01 |
| CN101855241A (zh) | 2010-10-06 |
| CA2672049A1 (en) | 2008-06-19 |
| EP2121751A4 (en) | 2012-01-11 |
| MX2009006082A (es) | 2009-08-18 |
| HUE033960T2 (en) | 2018-01-29 |
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