AU2007250210B2 - 4,5-diphenyl-pyrimidinyl-oxy or -mercapto substituted carboxylic acids, method for the production and use thereof as medicaments - Google Patents

Info

Publication number

AU2007250210B2

AU2007250210B2 AU2007250210A AU2007250210A AU2007250210B2 AU 2007250210 B2 AU2007250210 B2 AU 2007250210B2 AU 2007250210 A AU2007250210 A AU 2007250210A AU 2007250210 A AU2007250210 A AU 2007250210A AU 2007250210 B2 AU2007250210 B2 AU 2007250210B2

Authority

AU

Australia

Prior art keywords

alkyl

inhibitors

agonists

compound

formula

Prior art date

2006-05-11

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Ceased

Links

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• -1 4,5-diphenyl-pyrimidinyl-oxy Chemical group 0.000 title claims abstract description 31
• 238000000034 method Methods 0.000 title claims description 20
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• 238000004519 manufacturing process Methods 0.000 title claims description 6
• 150000001735 carboxylic acids Chemical class 0.000 title abstract description 4
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• 150000003839 salts Chemical class 0.000 claims abstract description 21
• 238000011282 treatment Methods 0.000 claims abstract description 13
• 206010012601 diabetes mellitus Diseases 0.000 claims abstract description 8
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• 239000000556 agonist Substances 0.000 claims description 32
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• 229910052731 fluorine Inorganic materials 0.000 claims description 30
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• HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 claims description 4
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