AU2006299184B8 - Novel nitrocatechol derivatives having selectin ligand activity - Google Patents
Novel nitrocatechol derivatives having selectin ligand activity Download PDFInfo
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- AU2006299184B8 AU2006299184B8 AU2006299184A AU2006299184A AU2006299184B8 AU 2006299184 B8 AU2006299184 B8 AU 2006299184B8 AU 2006299184 A AU2006299184 A AU 2006299184A AU 2006299184 A AU2006299184 A AU 2006299184A AU 2006299184 B8 AU2006299184 B8 AU 2006299184B8
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- selectin
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
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- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A61K31/19—Carboxylic acids, e.g. valproic acid
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- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
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- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/38—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05020508A EP1764095A1 (en) | 2005-09-20 | 2005-09-20 | Novel nitrocatechol derivatives having selectin ligand activity |
| EP05020508.7 | 2005-09-20 | ||
| PCT/EP2006/009155 WO2007039114A1 (en) | 2005-09-20 | 2006-09-20 | Novel nitrocatechol derivatives having selectin ligand activity |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| AU2006299184A1 AU2006299184A1 (en) | 2007-04-12 |
| AU2006299184B2 AU2006299184B2 (en) | 2012-08-09 |
| AU2006299184B8 true AU2006299184B8 (en) | 2012-12-06 |
| AU2006299184A8 AU2006299184A8 (en) | 2012-12-06 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2006299184A Ceased AU2006299184B8 (en) | 2005-09-20 | 2006-09-20 | Novel nitrocatechol derivatives having selectin ligand activity |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7851501B2 (https=) |
| EP (2) | EP1764095A1 (https=) |
| JP (1) | JP2009508902A (https=) |
| CN (2) | CN103230389A (https=) |
| AU (1) | AU2006299184B8 (https=) |
| BR (1) | BRPI0616391A2 (https=) |
| CA (1) | CA2622935A1 (https=) |
| IL (1) | IL190157A0 (https=) |
| RU (1) | RU2428979C2 (https=) |
| WO (1) | WO2007039114A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6838452B2 (en) * | 2000-11-24 | 2005-01-04 | Vascular Biogenics Ltd. | Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis |
| EP1577289A1 (en) * | 2004-03-18 | 2005-09-21 | Revotar Biopharmaceuticals AG | Non-glycosylated/-glycosidic/-peptidic small molecule selectin inhibitors for the treament of inflammatory disorders |
| EP1764096A1 (en) | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Novel phloroglucinol derivatives having selectin ligand activity |
| EP1764094A1 (en) * | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Novel multi-cyclic compounds and their use |
| EP1764093A1 (en) * | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Novel aromatic compounds and their use in medical applications |
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2006
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- 2006-09-20 WO PCT/EP2006/009155 patent/WO2007039114A1/en not_active Ceased
- 2006-09-20 CN CN2006800387821A patent/CN101374508B/zh not_active Expired - Fee Related
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| US20090105280A1 (en) | 2009-04-23 |
| US20110053939A1 (en) | 2011-03-03 |
| AU2006299184A1 (en) | 2007-04-12 |
| US7851501B2 (en) | 2010-12-14 |
| AU2006299184B2 (en) | 2012-08-09 |
| RU2008115464A (ru) | 2009-10-27 |
| BRPI0616391A2 (pt) | 2011-06-21 |
| RU2428979C2 (ru) | 2011-09-20 |
| CN103230389A (zh) | 2013-08-07 |
| JP2009508902A (ja) | 2009-03-05 |
| IL190157A0 (en) | 2008-08-07 |
| EP1764095A1 (en) | 2007-03-21 |
| EP1937238A1 (en) | 2008-07-02 |
| CN101374508A (zh) | 2009-02-25 |
| CA2622935A1 (en) | 2007-04-12 |
| CN101374508B (zh) | 2013-04-24 |
| AU2006299184A8 (en) | 2012-12-06 |
| WO2007039114A1 (en) | 2007-04-12 |
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