AU2006271383A1 - Use of thiazole derivatives and analogues in disorders caused by free fatty acids - Google Patents

Info

Publication number

AU2006271383A1

AU2006271383A1 AU2006271383A AU2006271383A AU2006271383A1 AU 2006271383 A1 AU2006271383 A1 AU 2006271383A1 AU 2006271383 A AU2006271383 A AU 2006271383A AU 2006271383 A AU2006271383 A AU 2006271383A AU 2006271383 A1 AU2006271383 A1 AU 2006271383A1

Authority

AU

Australia

Prior art keywords

compound

formula

benzyl

title compound

thiazolidin

Prior art date

2005-07-21

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Abandoned

Links

• Espacenet
• Global Dossier
• Discuss

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• 150000007979 thiazole derivatives Chemical class 0.000 title description 2
• 150000001875 compounds Chemical class 0.000 claims description 420
• 238000000034 method Methods 0.000 claims description 113
• 125000003118 aryl group Chemical group 0.000 claims description 66
• 125000000217 alkyl group Chemical group 0.000 claims description 57
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• 238000006243 chemical reaction Methods 0.000 claims description 42
• 125000001072 heteroaryl group Chemical group 0.000 claims description 42
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 39
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• 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims description 19
• 125000000753 cycloalkyl group Chemical group 0.000 claims description 19
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• MGJFLAHLODASKL-UHFFFAOYSA-N 2-(4-chloroanilino)-5-[[3-(trifluoromethyl)phenyl]methyl]-1,3-thiazol-4-one Chemical compound FC(F)(F)C1=CC=CC(CC2C(N=C(NC=3C=CC(Cl)=CC=3)S2)=O)=C1 MGJFLAHLODASKL-UHFFFAOYSA-N 0.000 claims description 5
• LKJFEVJLZCHMNR-UHFFFAOYSA-N 2-(4-methylanilino)-5-[[3-(trifluoromethyl)phenyl]methyl]-1,3-thiazol-4-one Chemical compound C1=CC(C)=CC=C1NC(S1)=NC(=O)C1CC1=CC=CC(C(F)(F)F)=C1 LKJFEVJLZCHMNR-UHFFFAOYSA-N 0.000 claims description 5
• OJOXIPILLXOGHW-UHFFFAOYSA-N 5-[(4-fluorophenyl)methyl]-2-(pyridin-2-ylamino)-1,3-thiazol-4-one Chemical compound C1=CC(F)=CC=C1CC1C(=O)N=C(NC=2N=CC=CC=2)S1 OJOXIPILLXOGHW-UHFFFAOYSA-N 0.000 claims description 5
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• 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 claims description 3
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