AU2006270110A1 - Identification of a novel bitter taste receptor T2R76 that specifically responds to brucine and prop bitter ligands - Google Patents

Identification of a novel bitter taste receptor T2R76 that specifically responds to brucine and prop bitter ligands Download PDF

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Publication number
AU2006270110A1
AU2006270110A1 AU2006270110A AU2006270110A AU2006270110A1 AU 2006270110 A1 AU2006270110 A1 AU 2006270110A1 AU 2006270110 A AU2006270110 A AU 2006270110A AU 2006270110 A AU2006270110 A AU 2006270110A AU 2006270110 A1 AU2006270110 A1 AU 2006270110A1
Authority
AU
Australia
Prior art keywords
polypeptide
nucleic acid
seq
acid molecule
assay
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2006270110A
Other languages
English (en)
Inventor
Xiaodong Li
Hong Xu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Firmenich Inc
Original Assignee
Senomyx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senomyx Inc filed Critical Senomyx Inc
Publication of AU2006270110A1 publication Critical patent/AU2006270110A1/en
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
AU2006270110A 2005-07-18 2006-07-17 Identification of a novel bitter taste receptor T2R76 that specifically responds to brucine and prop bitter ligands Abandoned AU2006270110A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/182,942 2005-07-18
US11/182,942 US20060019346A1 (en) 2002-07-29 2005-07-18 Identification of a novel bitter taste receptor T2R76 that specifically responds to brucine and prop bitter ligands
PCT/US2006/027656 WO2007011859A2 (en) 2005-07-18 2006-07-17 Identification of a novel bitter taste receptor t2r76 that specifically responds to brucine and prop bitter ligands

Publications (1)

Publication Number Publication Date
AU2006270110A1 true AU2006270110A1 (en) 2007-01-25

Family

ID=37669462

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006270110A Abandoned AU2006270110A1 (en) 2005-07-18 2006-07-17 Identification of a novel bitter taste receptor T2R76 that specifically responds to brucine and prop bitter ligands

Country Status (10)

Country Link
US (1) US20060019346A1 (https=)
EP (1) EP1904527A4 (https=)
JP (1) JP2009514507A (https=)
CN (1) CN101595118A (https=)
AU (1) AU2006270110A1 (https=)
CA (1) CA2610237A1 (https=)
IL (1) IL187827A0 (https=)
MX (1) MX2007015930A (https=)
NO (1) NO20076201L (https=)
WO (1) WO2007011859A2 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004011617A2 (en) * 2002-07-29 2004-02-05 Senomyx, Inc. Identification of a novel bitter taste receptor, t2r76
WO2006068745A1 (en) 2004-12-22 2006-06-29 Cargill, Incorporated Methods for determining cellular response to stimuli
WO2008008224A2 (en) 2006-07-10 2008-01-17 Duke University Sour taste receptor compositions and methods
EP2245171A2 (en) * 2008-02-01 2010-11-03 Chromocell Corporation Cell lines and methods for making and using them
US8557530B2 (en) 2008-08-29 2013-10-15 Givaudan Sa Use of a TAS2R7 nucleic acid sequence to identify modulators
CN103068380A (zh) * 2010-06-17 2013-04-24 加州理工学院 用于调节激素的方法和系统以及相关的方法、剂和组合物
HUE051738T2 (hu) 2011-01-07 2021-03-29 Anji Pharma Us Llc Kemoszenzoros receptorligandum-alapú terápiák
US9795792B2 (en) 2011-02-25 2017-10-24 Medtronic, Inc. Emergency mode switching for non-pacing modes
KR20200137035A (ko) 2012-01-06 2020-12-08 앤지 파마 유에스 엘엘씨 바이구아나이드 조성물 및 대사 장애를 치료하는 방법
EA033067B1 (ru) 2012-01-06 2019-08-30 Элселикс Терапьютикс, Инк. Способ лечения метаболических расстройств у пациента, имеющего противопоказание к назначению бигуанидного соединения
CA2878625A1 (en) 2012-07-11 2014-01-16 Elcelyx Therapeutics, Inc. Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk
CN105101956B (zh) 2013-01-05 2018-12-07 埃尔舍利克斯治疗公司 包含双胍的延迟释放组合物
EP4566459A3 (en) * 2018-08-10 2025-08-20 Firmenich Incorporated Antagonists of t2r54 and compositions and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6004808A (en) * 1996-06-21 1999-12-21 Aurora Biosciences Corporation Promiscuous G-protein compositions and their use
JP2003057981A (ja) * 2001-08-17 2003-02-28 Nitto Kogyo Co Ltd 定着装置
WO2004011617A2 (en) * 2002-07-29 2004-02-05 Senomyx, Inc. Identification of a novel bitter taste receptor, t2r76

Also Published As

Publication number Publication date
WO2007011859A2 (en) 2007-01-25
EP1904527A2 (en) 2008-04-02
CA2610237A1 (en) 2007-01-25
MX2007015930A (es) 2008-03-06
EP1904527A4 (en) 2010-05-05
JP2009514507A (ja) 2009-04-09
NO20076201L (no) 2008-04-17
WO2007011859A3 (en) 2009-08-27
IL187827A0 (en) 2008-03-20
US20060019346A1 (en) 2006-01-26
CN101595118A (zh) 2009-12-02

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period