NO20076201L - Identifikasjon av en ny bitter smak reseptor T2R76 som spesifikt responderer til brucin og PROP bitter ligander - Google Patents
Identifikasjon av en ny bitter smak reseptor T2R76 som spesifikt responderer til brucin og PROP bitter liganderInfo
- Publication number
- NO20076201L NO20076201L NO20076201A NO20076201A NO20076201L NO 20076201 L NO20076201 L NO 20076201L NO 20076201 A NO20076201 A NO 20076201A NO 20076201 A NO20076201 A NO 20076201A NO 20076201 L NO20076201 L NO 20076201L
- Authority
- NO
- Norway
- Prior art keywords
- bitter
- brucine
- prop
- identification
- polypeptides
- Prior art date
Links
- 235000019658 bitter taste Nutrition 0.000 title abstract 2
- RRKTZKIUPZVBMF-IBTVXLQLSA-N brucine Chemical compound O([C@@H]1[C@H]([C@H]2C3)[C@@H]4N(C(C1)=O)C=1C=C(C(=CC=11)OC)OC)CC=C2CN2[C@@H]3[C@]41CC2 RRKTZKIUPZVBMF-IBTVXLQLSA-N 0.000 title 1
- RRKTZKIUPZVBMF-UHFFFAOYSA-N brucine Natural products C1=2C=C(OC)C(OC)=CC=2N(C(C2)=O)C3C(C4C5)C2OCC=C4CN2C5C31CC2 RRKTZKIUPZVBMF-UHFFFAOYSA-N 0.000 title 1
- 108091005708 gustatory receptors Proteins 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 6
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 6
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 6
- 238000002474 experimental method Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 238000003259 recombinant expression Methods 0.000 abstract 1
- 230000014860 sensory perception of taste Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/182,942 US20060019346A1 (en) | 2002-07-29 | 2005-07-18 | Identification of a novel bitter taste receptor T2R76 that specifically responds to brucine and prop bitter ligands |
| PCT/US2006/027656 WO2007011859A2 (en) | 2005-07-18 | 2006-07-17 | Identification of a novel bitter taste receptor t2r76 that specifically responds to brucine and prop bitter ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20076201L true NO20076201L (no) | 2008-04-17 |
Family
ID=37669462
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20076201A NO20076201L (no) | 2005-07-18 | 2007-12-03 | Identifikasjon av en ny bitter smak reseptor T2R76 som spesifikt responderer til brucin og PROP bitter ligander |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20060019346A1 (https=) |
| EP (1) | EP1904527A4 (https=) |
| JP (1) | JP2009514507A (https=) |
| CN (1) | CN101595118A (https=) |
| AU (1) | AU2006270110A1 (https=) |
| CA (1) | CA2610237A1 (https=) |
| IL (1) | IL187827A0 (https=) |
| MX (1) | MX2007015930A (https=) |
| NO (1) | NO20076201L (https=) |
| WO (1) | WO2007011859A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004011617A2 (en) * | 2002-07-29 | 2004-02-05 | Senomyx, Inc. | Identification of a novel bitter taste receptor, t2r76 |
| WO2006068745A1 (en) | 2004-12-22 | 2006-06-29 | Cargill, Incorporated | Methods for determining cellular response to stimuli |
| WO2008008224A2 (en) | 2006-07-10 | 2008-01-17 | Duke University | Sour taste receptor compositions and methods |
| EP2245171A2 (en) * | 2008-02-01 | 2010-11-03 | Chromocell Corporation | Cell lines and methods for making and using them |
| US8557530B2 (en) | 2008-08-29 | 2013-10-15 | Givaudan Sa | Use of a TAS2R7 nucleic acid sequence to identify modulators |
| CN103068380A (zh) * | 2010-06-17 | 2013-04-24 | 加州理工学院 | 用于调节激素的方法和系统以及相关的方法、剂和组合物 |
| HUE051738T2 (hu) | 2011-01-07 | 2021-03-29 | Anji Pharma Us Llc | Kemoszenzoros receptorligandum-alapú terápiák |
| US9795792B2 (en) | 2011-02-25 | 2017-10-24 | Medtronic, Inc. | Emergency mode switching for non-pacing modes |
| KR20200137035A (ko) | 2012-01-06 | 2020-12-08 | 앤지 파마 유에스 엘엘씨 | 바이구아나이드 조성물 및 대사 장애를 치료하는 방법 |
| EA033067B1 (ru) | 2012-01-06 | 2019-08-30 | Элселикс Терапьютикс, Инк. | Способ лечения метаболических расстройств у пациента, имеющего противопоказание к назначению бигуанидного соединения |
| CA2878625A1 (en) | 2012-07-11 | 2014-01-16 | Elcelyx Therapeutics, Inc. | Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk |
| CN105101956B (zh) | 2013-01-05 | 2018-12-07 | 埃尔舍利克斯治疗公司 | 包含双胍的延迟释放组合物 |
| EP4566459A3 (en) * | 2018-08-10 | 2025-08-20 | Firmenich Incorporated | Antagonists of t2r54 and compositions and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6004808A (en) * | 1996-06-21 | 1999-12-21 | Aurora Biosciences Corporation | Promiscuous G-protein compositions and their use |
| JP2003057981A (ja) * | 2001-08-17 | 2003-02-28 | Nitto Kogyo Co Ltd | 定着装置 |
| WO2004011617A2 (en) * | 2002-07-29 | 2004-02-05 | Senomyx, Inc. | Identification of a novel bitter taste receptor, t2r76 |
-
2005
- 2005-07-18 US US11/182,942 patent/US20060019346A1/en not_active Abandoned
-
2006
- 2006-07-17 CN CNA2006800235890A patent/CN101595118A/zh active Pending
- 2006-07-17 MX MX2007015930A patent/MX2007015930A/es not_active Application Discontinuation
- 2006-07-17 AU AU2006270110A patent/AU2006270110A1/en not_active Abandoned
- 2006-07-17 CA CA002610237A patent/CA2610237A1/en not_active Abandoned
- 2006-07-17 EP EP06800086A patent/EP1904527A4/en not_active Withdrawn
- 2006-07-17 WO PCT/US2006/027656 patent/WO2007011859A2/en not_active Ceased
- 2006-07-17 JP JP2008522858A patent/JP2009514507A/ja not_active Withdrawn
-
2007
- 2007-12-03 IL IL187827A patent/IL187827A0/en unknown
- 2007-12-03 NO NO20076201A patent/NO20076201L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007011859A2 (en) | 2007-01-25 |
| EP1904527A2 (en) | 2008-04-02 |
| CA2610237A1 (en) | 2007-01-25 |
| MX2007015930A (es) | 2008-03-06 |
| EP1904527A4 (en) | 2010-05-05 |
| AU2006270110A1 (en) | 2007-01-25 |
| JP2009514507A (ja) | 2009-04-09 |
| WO2007011859A3 (en) | 2009-08-27 |
| IL187827A0 (en) | 2008-03-20 |
| US20060019346A1 (en) | 2006-01-26 |
| CN101595118A (zh) | 2009-12-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20076201L (no) | Identifikasjon av en ny bitter smak reseptor T2R76 som spesifikt responderer til brucin og PROP bitter ligander | |
| MX2021000047A (es) | Proteina de fusion variante pd1-4-1bbl y procedimientos de uso de la misma. | |
| WO2007064917A3 (en) | Methods of preparation of recombinant forms of human beta-amyloid protein and uses of these proteins | |
| WO2019191633A3 (en) | Lysin-antimicrobial peptide (amp) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof | |
| NO20045650L (no) | Identifisering av en ny bitter smaksreseptor , T2R76 | |
| WO2013040093A3 (en) | Glucagon-like peptide-2 compositions and methods of making and using same | |
| AU2017263237A1 (en) | GDF15 fusion proteins and uses thereof | |
| MX2011008094A (es) | Polipeptidos recombinantes extendidos y composiciones que comprenden los mismos. | |
| BRPI0512286A (pt) | proteìnas quiméricas inibidoras da angiogênese e o uso | |
| WO2004053059A3 (en) | Mitoneet polypeptide from mitochondrial membranes, modulators thereof, and methods of using the same | |
| WO2009081368A3 (en) | Cosmetic use desmoglein i-type proteins | |
| HK1220466A1 (zh) | 爱帕琳融合蛋白和其用途 | |
| MX2021000263A (es) | Proteina de fusion variante sirpalfa-4-1bbl y procedimientos de uso de la misma. | |
| WO2009081374A3 (en) | Cosmetic use of plakoglobin-type proteins | |
| WO2008040190A8 (fr) | Petits peptides pour anti-angiogenèse et utilisation de ceux-ci | |
| WO2002070549A3 (en) | Chimeric polypeptides of serum albumin and uses related thereto | |
| WO2003072751A3 (en) | Expression system for human brain-specific voltage-gated sodium channel, type 1 | |
| WO2005021029A3 (en) | Preventive cancer vaccine based on brother of regulator of imprinted sites molecule (boris) | |
| WO2005116660A3 (en) | Methods for making and using mass tag standards for quantitative proteomics | |
| WO2005017188A3 (en) | Fusion proteins with a membrane translocating sequence and methods of using same to inhibit an immune response | |
| WO2005049806A3 (en) | Novel nucleic acids and polypeptides | |
| DE60235985D1 (de) | Ntb-a, ein oberflächenmolekül impliziert in der aktivität natürlicher killerzellen (nk) | |
| WO2006096816A3 (en) | Human leptin-derived polypeptides and uses thereof | |
| WO2002077241A3 (en) | Isolated human metalloprotease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof | |
| WO2004053092A3 (en) | Human pellino polypeptides |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |