NO20045650L - Identifisering av en ny bitter smaksreseptor , T2R76 - Google Patents

Identifisering av en ny bitter smaksreseptor , T2R76

Info

Publication number
NO20045650L
NO20045650L NO20045650A NO20045650A NO20045650L NO 20045650 L NO20045650 L NO 20045650L NO 20045650 A NO20045650 A NO 20045650A NO 20045650 A NO20045650 A NO 20045650A NO 20045650 L NO20045650 L NO 20045650L
Authority
NO
Norway
Prior art keywords
polypeptides
identification
bitter taste
taste receptor
expressed
Prior art date
Application number
NO20045650A
Other languages
English (en)
Inventor
Jon Elliot Adler
Mark Zoller
Huixian Tang
Alexey Pronin
Original Assignee
Senomyx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senomyx Inc filed Critical Senomyx Inc
Publication of NO20045650L publication Critical patent/NO20045650L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

S a m m e n d r a g Det beskrives isolerte nukleinsyrer som koder for T2R76-polypeptider, rekombinant uttrykte T2R76-polypeptider, heterologe ekspresjonssystemer for rekombinant ekspresjon av T2R76-polypeptider, testmetoder som anvender disse, og fremgangsmåter for å endre smaks-persepsjon ved å administrere en T2R76modulator. Disse T2R76-polypeptidene kan uttrykkes alene eller uttrykkes sammen med et annet T2R-polypeptid, fortrinnsvis et forskjellig humant T2R-polypeptid.
NO20045650A 2002-07-29 2004-12-27 Identifisering av en ny bitter smaksreseptor , T2R76 NO20045650L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39872702P 2002-07-29 2002-07-29
PCT/US2003/023604 WO2004011617A2 (en) 2002-07-29 2003-07-29 Identification of a novel bitter taste receptor, t2r76

Publications (1)

Publication Number Publication Date
NO20045650L true NO20045650L (no) 2005-02-23

Family

ID=31188466

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20045650A NO20045650L (no) 2002-07-29 2004-12-27 Identifisering av en ny bitter smaksreseptor , T2R76

Country Status (10)

Country Link
US (2) US7517972B2 (no)
EP (1) EP1572960A4 (no)
JP (2) JP2006515157A (no)
CN (1) CN1984919A (no)
AU (1) AU2003261280B2 (no)
CA (1) CA2488863A1 (no)
IL (1) IL165669A0 (no)
MX (1) MXPA04012334A (no)
NO (1) NO20045650L (no)
WO (1) WO2004011617A2 (no)

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* Cited by examiner, † Cited by third party
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TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
US7803982B2 (en) 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods
US20060019346A1 (en) * 2002-07-29 2006-01-26 Senomyx, Inc. Identification of a novel bitter taste receptor T2R76 that specifically responds to brucine and prop bitter ligands
US7517972B2 (en) * 2002-07-29 2009-04-14 Senomyx, Inc. Nucleic acid sequences encoding a bitter taste receptor, T2R76
BRPI0413324A (pt) * 2003-08-06 2006-10-10 Senomyx Inc receptores de paladar hetero-oligoméricos t1r, linhas de células que expressam os ditos receptores, e compostos de paladar
US20060045953A1 (en) * 2004-08-06 2006-03-02 Catherine Tachdjian Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
WO2006068745A1 (en) 2004-12-22 2006-06-29 Cargill, Incorporated Methods for determining cellular response to stimuli
ZA200707482B (en) 2005-02-04 2008-12-31 Senomyx Inc Compounds comprising linked heteroaryl moieties and their use as novel umami flavour modifiers, tastants and taste enhancers for comestible compositions
TW200638882A (en) * 2005-02-04 2006-11-16 Senomyx Inc Molecules comprising linked organic moieties as flavor modifiers for comestible compositions
AR055329A1 (es) 2005-06-15 2007-08-15 Senomyx Inc Amidas bis-aromaticas y sus usos como modificadores de sabor dulce, saborizantes, y realzadores de sabor
AU2006262399A1 (en) * 2005-06-22 2007-01-04 Senomyx, Inc. Identification of human T2R recepors that are activated by bitter molecules in coffee (chlorogenic lactones) and related assays for identifying human bitter taste modulators
WO2007124152A2 (en) 2006-04-21 2007-11-01 Senomyx, Inc. Comestible compositions comprising high potency savory flavorants, and processes for producing them
WO2008008224A2 (en) * 2006-07-10 2008-01-17 Duke University Sour taste receptor compositions and methods
CN101960014B (zh) * 2008-02-01 2013-10-16 克罗莫塞尔公司 细胞系以及制备和使用其的方法
JP5906013B2 (ja) * 2010-12-10 2016-04-20 花王株式会社 苦味抑制剤の評価・選択方法
US9128079B2 (en) 2011-08-08 2015-09-08 The Coca-Cola Company Methods of using lung or bronchial epithelial cells to identify bitter taste modulators
CA2911189A1 (en) 2013-05-10 2014-11-13 Pepsico, Inc. Taste receptor internalization assay
AU2014262543B2 (en) 2013-05-10 2017-07-20 Pepsico, Inc. Cells as a model to identify potential taste modulators
CN106170488B (zh) 2014-02-12 2020-09-18 弗门尼舍公司 用于取代的1-苄基-3-(1-(异噁唑-4-基甲基)-1h-吡唑-4-基)咪唑烷-2,4-二酮的合成的改进方法
EP3793427A1 (en) 2018-05-17 2021-03-24 The Procter & Gamble Company Systems and methods for hair coverage analysis
US11172873B2 (en) 2018-05-17 2021-11-16 The Procter & Gamble Company Systems and methods for hair analysis
US11384357B2 (en) 2018-06-29 2022-07-12 The Procter And Gamble Company Aptamers for personal care applications
EP3956451A1 (en) 2019-04-16 2022-02-23 The Procter & Gamble Company Aptamers for odor control applications
US12039732B2 (en) 2021-04-14 2024-07-16 The Procter & Gamble Company Digital imaging and learning systems and methods for analyzing pixel data of a scalp region of a users scalp to generate one or more user-specific scalp classifications

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US7517972B2 (en) * 2002-07-29 2009-04-14 Senomyx, Inc. Nucleic acid sequences encoding a bitter taste receptor, T2R76

Also Published As

Publication number Publication date
WO2004011617A2 (en) 2004-02-05
US8338115B2 (en) 2012-12-25
AU2003261280B2 (en) 2009-02-05
IL165669A0 (en) 2006-01-15
JP2006515157A (ja) 2006-05-25
EP1572960A4 (en) 2009-03-18
US7517972B2 (en) 2009-04-14
EP1572960A2 (en) 2005-09-14
WO2004011617A3 (en) 2007-03-01
CA2488863A1 (en) 2004-02-05
AU2003261280A1 (en) 2004-02-16
US20040132134A1 (en) 2004-07-08
WO2004011617A8 (en) 2009-04-09
MXPA04012334A (es) 2005-07-25
CN1984919A (zh) 2007-06-20
US20090203027A1 (en) 2009-08-13
JP2009145349A (ja) 2009-07-02

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