AU2006214655A1 - Polymer particle delivery compositions and methods of use - Google Patents
Polymer particle delivery compositions and methods of use Download PDFInfo
- Publication number
- AU2006214655A1 AU2006214655A1 AU2006214655A AU2006214655A AU2006214655A1 AU 2006214655 A1 AU2006214655 A1 AU 2006214655A1 AU 2006214655 A AU2006214655 A AU 2006214655A AU 2006214655 A AU2006214655 A AU 2006214655A AU 2006214655 A1 AU2006214655 A1 AU 2006214655A1
- Authority
- AU
- Australia
- Prior art keywords
- polymer
- composition
- alkyl
- particles
- bioactive agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/595—Polyamides, e.g. nylon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
- A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L77/00—Compositions of polyamides obtained by reactions forming a carboxylic amide link in the main chain; Compositions of derivatives of such polymers
- C08L77/12—Polyester-amides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
Applications Claiming Priority (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65471505P | 2005-02-17 | 2005-02-17 | |
US60/654,715 | 2005-02-17 | ||
US68467005P | 2005-05-25 | 2005-05-25 | |
US60/684,670 | 2005-05-25 | ||
US68757005P | 2005-06-03 | 2005-06-03 | |
US60/687,570 | 2005-06-03 | ||
US71995005P | 2005-09-22 | 2005-09-22 | |
US60/719,950 | 2005-09-22 | ||
US73740105P | 2005-11-14 | 2005-11-14 | |
US60/737,401 | 2005-11-14 | ||
US75917906P | 2006-01-13 | 2006-01-13 | |
US60/759,179 | 2006-01-13 | ||
PCT/US2006/003575 WO2006088647A1 (en) | 2005-02-17 | 2006-01-31 | Polymer particle delivery compositions and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2006214655A1 true AU2006214655A1 (en) | 2006-08-24 |
Family
ID=36916776
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2006214655A Abandoned AU2006214655A1 (en) | 2005-02-17 | 2006-01-31 | Polymer particle delivery compositions and methods of use |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1848410A4 (de) |
JP (1) | JP2008530206A (de) |
CN (1) | CN101115471B (de) |
AU (1) | AU2006214655A1 (de) |
CA (1) | CA2596011C (de) |
WO (1) | WO2006088647A1 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060177416A1 (en) | 2003-10-14 | 2006-08-10 | Medivas, Llc | Polymer particle delivery compositions and methods of use |
CA2623198C (en) | 2005-09-22 | 2014-08-05 | Medivas, Llc | Bis-(a-amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use |
EP1933881B1 (de) | 2005-09-22 | 2019-03-13 | Medivas, LLC | Feste polymer-abgabezusammensetzungen und anwendungsverfahren dafür |
JP2009530484A (ja) * | 2006-03-24 | 2009-08-27 | メディバス エルエルシー | アルキレン−ジカルボキシラート含有の生分解性ポリ(エステル−アミド)および使用法 |
US8658210B2 (en) | 2006-04-17 | 2014-02-25 | Advanced Cardiovascular Systems, Inc. | Polyesteramide platform for site specific drug delivery |
WO2007133616A2 (en) * | 2006-05-09 | 2007-11-22 | Medivas, Llc | Biodegradable water soluble polymers |
WO2008082721A2 (en) * | 2006-09-05 | 2008-07-10 | Medivas, Llc | Polymer-stabilized liposomal compositions and methods of use |
WO2009026543A2 (en) * | 2007-08-23 | 2009-02-26 | Medivas, Llc | Cationic alpha-amino acid-containing biodegradable polymer gene transfer compositions |
US9732142B2 (en) | 2008-05-15 | 2017-08-15 | Biocompatibles Uk Limited | Intracellular antibody delivery |
JP2012505957A (ja) * | 2008-10-15 | 2012-03-08 | メディバス エルエルシー | プロリンベースの生分解性ポリマー |
US9873765B2 (en) | 2011-06-23 | 2018-01-23 | Dsm Ip Assets, B.V. | Biodegradable polyesteramide copolymers for drug delivery |
EP2723800B1 (de) | 2011-06-23 | 2015-10-07 | DSM IP Assets B.V. | Mikro- oder nanopartikel mit einem biologisch abbaubaren polyesteramid-copolymer zur verwendung bei der verabreichung von bioaktiven substanzen |
US10434071B2 (en) | 2014-12-18 | 2019-10-08 | Dsm Ip Assets, B.V. | Drug delivery system for delivery of acid sensitivity drugs |
CA2988679A1 (en) * | 2015-06-23 | 2016-12-29 | Phagelux (Canada), Inc. | Composition comprising amino acid polymers and a bioactive agent and method of preparing thereof |
US11090273B2 (en) * | 2016-09-20 | 2021-08-17 | Cornell University | Tagged poly(ester amide urethane)s, nanoparticles formed from same, and uses thereof |
CN112321822B (zh) * | 2020-12-02 | 2021-12-10 | 中山大学 | 一种具有ros响应性的蛋氨酸-聚酯酰胺高分子聚合物及其应用 |
CN114920869B (zh) * | 2022-05-24 | 2023-07-14 | 太原工业学院 | 两亲性精氨酸嵌段环丙沙星共聚物、纳米颗粒及其制备方法和应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU222501B1 (hu) * | 1991-06-28 | 2003-07-28 | Endorecherche Inc. | MPA-t vagy MGA-t tartalmazó nyújtott hatóanyag-felszabadulású gyógyászati készítmény és eljárás előállítására |
KR940003548U (ko) * | 1992-08-14 | 1994-02-21 | 김형술 | 세탁물 건조기 |
US5874064A (en) * | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
US20020164374A1 (en) * | 1997-10-29 | 2002-11-07 | John Jackson | Polymeric systems for drug delivery and uses thereof |
JP4570776B2 (ja) * | 1997-12-12 | 2010-10-27 | サミアン・コーポレーション | 遺伝子輸送のための生物分解性の混合重合体ミセル |
CN1339964A (zh) * | 1999-02-19 | 2002-03-13 | 生化研究股份公司 | 用以生产微胶囊的生物可降解复合材料 |
WO2001051027A2 (en) * | 2000-01-11 | 2001-07-19 | Intralytix, Inc. | Polymer blends as biodegradable matrices for preparing biocomposites |
US6703040B2 (en) * | 2000-01-11 | 2004-03-09 | Intralytix, Inc. | Polymer blends as biodegradable matrices for preparing biocomposites |
DE60141680D1 (de) * | 2000-01-14 | 2010-05-12 | Univ Brown Res Found | Verfahren zur herstellung von mikronisierte gefriergetrocknete partikeln |
FR2811227A1 (fr) * | 2000-07-07 | 2002-01-11 | Philippe Maincent | Vecteurs particulaires destines a ameliorer l'absorption orale de principes actifs |
US6503538B1 (en) * | 2000-08-30 | 2003-01-07 | Cornell Research Foundation, Inc. | Elastomeric functional biodegradable copolyester amides and copolyester urethanes |
CN1119172C (zh) * | 2000-12-12 | 2003-08-27 | 天津大学 | 脂肪族聚酯表面的壳聚糖/明胶网络修饰方法 |
WO2003062298A1 (en) * | 2002-01-17 | 2003-07-31 | Polyrava Llc | Co-poly(ester amide) and co-poly(ester urethane) compositions which exhibit biodegradability, methods for making same and uses for same |
WO2003075892A1 (en) * | 2002-03-13 | 2003-09-18 | Novartis Ag | Pharmaceutical microparticles |
DE60311801T2 (de) * | 2002-05-02 | 2007-11-08 | PR Pharmaceuticals, Inc., Fort Collins | Zusammensetzungen aus östradiol-metaboliten mit kontrollierter freisetzung |
CA2486104C (en) * | 2002-05-15 | 2014-07-29 | Rutgers, The State University | Tri-block polymers for nanosphere-based drug or gene delivery |
US20090007952A1 (en) * | 2004-10-18 | 2009-01-08 | Yoshiomi Kondoh | Structure of Peltier Element or Seebeck Element and Its Manufacturing Method |
US8765164B2 (en) * | 2005-10-21 | 2014-07-01 | Kenneth W. Carpenter | Poly(ester urea) polymers and methods of use |
-
2006
- 2006-01-31 EP EP06734169A patent/EP1848410A4/de not_active Withdrawn
- 2006-01-31 AU AU2006214655A patent/AU2006214655A1/en not_active Abandoned
- 2006-01-31 JP JP2007556163A patent/JP2008530206A/ja active Pending
- 2006-01-31 CA CA2596011A patent/CA2596011C/en active Active
- 2006-01-31 CN CN200680004221XA patent/CN101115471B/zh active Active
- 2006-01-31 WO PCT/US2006/003575 patent/WO2006088647A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
CN101115471A (zh) | 2008-01-30 |
WO2006088647A1 (en) | 2006-08-24 |
CA2596011A1 (en) | 2006-08-24 |
EP1848410A1 (de) | 2007-10-31 |
EP1848410A4 (de) | 2011-11-09 |
JP2008530206A (ja) | 2008-08-07 |
CN101115471B (zh) | 2011-02-09 |
CA2596011C (en) | 2013-05-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK3 | Application lapsed section 142(2)(c) - examination deferred under section 46 no request for examination |