AU2006206525A1 - Macrocyclic analogs for the treatment of immunoregulatory disorders and respiratory diseases - Google Patents
Macrocyclic analogs for the treatment of immunoregulatory disorders and respiratory diseases Download PDFInfo
- Publication number
- AU2006206525A1 AU2006206525A1 AU2006206525A AU2006206525A AU2006206525A1 AU 2006206525 A1 AU2006206525 A1 AU 2006206525A1 AU 2006206525 A AU2006206525 A AU 2006206525A AU 2006206525 A AU2006206525 A AU 2006206525A AU 2006206525 A1 AU2006206525 A1 AU 2006206525A1
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- Prior art keywords
- compound
- pct
- optionally substituted
- mmol
- alkyl
- Prior art date
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Classifications
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- C07—ORGANIC CHEMISTRY
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- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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Landscapes
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- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Transplantation (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64555205P | 2005-01-20 | 2005-01-20 | |
| US60/645,552 | 2005-01-20 | ||
| PCT/US2006/001747 WO2006078724A2 (en) | 2005-01-20 | 2006-01-19 | Macrocyclic analogs for the treatment of immunoregulatory disorders and respiratory diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2006206525A1 true AU2006206525A1 (en) | 2006-07-27 |
| AU2006206525A2 AU2006206525A2 (en) | 2006-07-27 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2006206525A Abandoned AU2006206525A1 (en) | 2005-01-20 | 2006-01-19 | Macrocyclic analogs for the treatment of immunoregulatory disorders and respiratory diseases |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7553842B2 (enExample) |
| EP (1) | EP1838316A4 (enExample) |
| JP (1) | JP2008528491A (enExample) |
| AU (1) | AU2006206525A1 (enExample) |
| CA (1) | CA2601380A1 (enExample) |
| MX (1) | MX2007008662A (enExample) |
| TW (1) | TW200637552A (enExample) |
| WO (1) | WO2006078724A2 (enExample) |
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| GB0904540D0 (en) * | 2009-03-17 | 2009-04-29 | Biotica Tech Ltd | Novel compounds and methods for their production |
| GB0917817D0 (en) * | 2009-10-12 | 2009-11-25 | Biotica Tech Ltd | Novel compounds and methods for their production |
| GB0917816D0 (en) * | 2009-10-12 | 2009-11-25 | Biotica Tech Ltd | Novel compounds and methods for their production |
| IT1401451B1 (it) * | 2010-06-10 | 2013-07-26 | Chemi Spa | Nuovo processo di preparazione di 2-idrossi-4-fenil-3,4-diidro-2h-cromen-6-il-metanolo e (r)-2-[3-(diisopropilammino)-1-fenilpropil]-4-(idrossimetil)fenolo. |
| WO2015073691A1 (en) | 2013-11-14 | 2015-05-21 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for treating cancer by activation of bmp signaling |
| AU2017238246B2 (en) * | 2016-03-24 | 2021-04-01 | The Administrators Of The Tulane Educational Fund | Conjugates of tacrolimus, their compositions, and their uses |
| RU2019117548A (ru) * | 2016-11-10 | 2020-12-10 | Новартис Аг | Усилители вмр |
| CN108148032B (zh) * | 2018-03-01 | 2019-12-13 | 北京海步医药科技股份有限公司 | 一种3,4-二氢-2h-1-苯并吡喃-2-羧酸类化合物的制备方法及其应用 |
| KR20210129058A (ko) * | 2019-01-23 | 2021-10-27 | 더 존스 홉킨스 유니버시티 | 비-면역억제성 fk506 유사체 및 이의 용도 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2245891A (en) | 1990-07-09 | 1992-01-15 | Fujisawa Pharmaceutical Co | Tricyclo compounds |
| US5565560A (en) | 1991-05-13 | 1996-10-15 | Merck & Co., Inc. | O-Aryl,O-alkyl,O-alkenyl and O-alkynylmacrolides having immunosuppressive activity |
| US5563172A (en) * | 1991-09-05 | 1996-10-08 | Abbott Laboratories | Macrocyclic amide and urea immunomodulators |
| US5457111A (en) * | 1991-09-05 | 1995-10-10 | Abbott Laboratories | Macrocyclic immunomodulators |
| US5252732A (en) * | 1991-09-09 | 1993-10-12 | Merck & Co., Inc. | D-heteroaryl, O-alkylheteroaryl, O-alkenylheteroaryl and O-alkynylheteroarylmacrolides having immunosuppressive activity |
| US5284877A (en) * | 1992-06-12 | 1994-02-08 | Merck & Co., Inc. | Alkyl and alkenyl macrolides having immunosuppressive activity |
| US5457194A (en) * | 1993-03-17 | 1995-10-10 | Abbott Laboratories | Substituted aliphatic amine-containing macrocyclic immunomodulators |
| JPH08507788A (ja) * | 1993-03-17 | 1996-08-20 | アボツト・ラボラトリーズ | 置換脂環式アミン含有大環状免疫調節剤 |
| EP0689545A4 (en) * | 1993-03-17 | 1996-04-24 | Abbott Lab | IMMUNOREGULATORS WITH MACROCYCLIC AMIDE AND UREA |
| WO1994021634A1 (en) * | 1993-03-17 | 1994-09-29 | Abbott Laboratories | Substituted alicyclic-aliphatic amine-containing macrocyclic immunomodulators |
| US6093615A (en) * | 1994-08-15 | 2000-07-25 | Micron Technology, Inc. | Method of fabricating a contact structure having a composite barrier layer between a platinum layer and a polysilicon plug |
| DE19859467C2 (de) * | 1998-12-22 | 2002-11-28 | Steag Micro Tech Gmbh | Substrathalter |
| US6569867B2 (en) | 1999-10-01 | 2003-05-27 | Kosan Biosciences, Inc. | Polyketide derivatives |
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2006
- 2006-01-19 WO PCT/US2006/001747 patent/WO2006078724A2/en not_active Ceased
- 2006-01-19 JP JP2007552233A patent/JP2008528491A/ja not_active Withdrawn
- 2006-01-19 CA CA002601380A patent/CA2601380A1/en not_active Abandoned
- 2006-01-19 MX MX2007008662A patent/MX2007008662A/es not_active Application Discontinuation
- 2006-01-19 EP EP06718768A patent/EP1838316A4/en not_active Withdrawn
- 2006-01-19 TW TW095102047A patent/TW200637552A/zh unknown
- 2006-01-19 US US11/334,858 patent/US7553842B2/en not_active Expired - Fee Related
- 2006-01-19 AU AU2006206525A patent/AU2006206525A1/en not_active Abandoned
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|---|---|
| MX2007008662A (es) | 2007-09-06 |
| TW200637552A (en) | 2006-11-01 |
| JP2008528491A (ja) | 2008-07-31 |
| WO2006078724A3 (en) | 2008-01-24 |
| US20060160838A1 (en) | 2006-07-20 |
| CA2601380A1 (en) | 2006-07-27 |
| AU2006206525A2 (en) | 2006-07-27 |
| WO2006078724A2 (en) | 2006-07-27 |
| EP1838316A4 (en) | 2012-01-25 |
| US7553842B2 (en) | 2009-06-30 |
| EP1838316A2 (en) | 2007-10-03 |
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