AU2005300241A1 - Methods for preparing indazole compounds - Google Patents

Methods for preparing indazole compounds Download PDF

Info

Publication number
AU2005300241A1
AU2005300241A1 AU2005300241A AU2005300241A AU2005300241A1 AU 2005300241 A1 AU2005300241 A1 AU 2005300241A1 AU 2005300241 A AU2005300241 A AU 2005300241A AU 2005300241 A AU2005300241 A AU 2005300241A AU 2005300241 A1 AU2005300241 A1 AU 2005300241A1
Authority
AU
Australia
Prior art keywords
formula
compound
alkyl
aryl
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2005300241A
Other languages
English (en)
Other versions
AU2005300241A2 (en
Inventor
Srinivasan Babu
Raymond Dagnino Jr.
Aubrey Haddach
Mark Bryan Mitchell
Michael Allen Ouellette
James Edward Saenz
Jayaram Katsuri Srirangam
Shu Yu
Scott Edward Zook
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of AU2005300241A1 publication Critical patent/AU2005300241A1/en
Publication of AU2005300241A2 publication Critical patent/AU2005300241A2/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AU2005300241A 2004-11-02 2005-10-21 Methods for preparing indazole compounds Abandoned AU2005300241A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US62471904P 2004-11-02 2004-11-02
US60/624,719 2004-11-02
US62480104P 2004-12-14 2004-12-14
US60/624,801 2004-12-14
PCT/IB2005/003348 WO2006048761A2 (fr) 2004-11-02 2005-10-21 Procedes de preparation de composes indazole

Publications (2)

Publication Number Publication Date
AU2005300241A1 true AU2005300241A1 (en) 2006-05-11
AU2005300241A2 AU2005300241A2 (en) 2006-05-11

Family

ID=35456957

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005300241A Abandoned AU2005300241A1 (en) 2004-11-02 2005-10-21 Methods for preparing indazole compounds

Country Status (9)

Country Link
EP (1) EP1814859A2 (fr)
KR (1) KR20070085727A (fr)
AU (1) AU2005300241A1 (fr)
CA (1) CA2591313A1 (fr)
IL (1) IL183605A0 (fr)
MX (1) MX2007006554A (fr)
RU (1) RU2007120635A (fr)
TW (1) TW200630345A (fr)
WO (1) WO2006048761A2 (fr)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2136284A1 (en) * 1971-02-08 1972-08-31 Diamond Shamrock Corp., Cleveland, Ohio (V.StA.) Herbicidal pyrrolidinyl-carboxanilides - from arylisocyanates and pyrrolidines in organic solvents
PE20010306A1 (es) * 1999-07-02 2001-03-29 Agouron Pharma Compuestos de indazol y composiciones farmaceuticas que los contienen utiles para la inhibicion de proteina kinasa

Also Published As

Publication number Publication date
IL183605A0 (en) 2007-09-20
EP1814859A2 (fr) 2007-08-08
KR20070085727A (ko) 2007-08-27
AU2005300241A2 (en) 2006-05-11
TW200630345A (en) 2006-09-01
RU2007120635A (ru) 2008-12-10
MX2007006554A (es) 2007-06-19
WO2006048761A3 (fr) 2006-06-22
CA2591313A1 (fr) 2006-05-11
WO2006048761A2 (fr) 2006-05-11

Similar Documents

Publication Publication Date Title
CA2586176A1 (fr) Methodes de preparation de composes d'indazole
CN101094836A (zh) 制备吲唑化合物的方法
JP5701824B2 (ja) 置換２−（２，６−ジオキソピペリジン−３−イル）−１−オキソイソインドリン類の調製方法
JP7398436B2 (ja) メチル６－（２，４－ジクロロフェニル）－５－［４－［（３ｓ）－１－（３－フルオロプロピル）ピロリジン－３－イル］オキシフェニル］－８，９－ジヒドロ－７ｈ－ベンゾ［７］アンヌレン－２－カルボキシレートの塩およびその製造方法
KR850000873B1 (ko) 삼-치환 이미다졸 유도체의 제조방법
IL197527A (en) History - 4-Oxoquoquinoline and Process and Intermediate Compounds for Preparation of Integration Inhibitors
JP2023162264A (ja) 細胞毒性ベンゾジアゼピン誘導体の調製方法
EP3376870B1 (fr) Procédé de préparation d'inhibiteurs de kinase et de leurs intermédiaires
JP6873053B2 (ja) タンパク質脱アセチル化阻害剤の製造方法
CA3158165A1 (fr) Procede de preparation de (2-cyanoethyl (4s)-4-(4-cyano-2-methoxy-phenyl)-5-hydroxy-2,8-dimethyl-1,4-dihydro-1,6-naphtyridin-3-carboxylate par separation racemique au moyen d'esters d'acide tartrique diastereoisomeres
JPH0479349B2 (fr)
CA2647457C (fr) Procede de reduction par un hydrure servant a preparer des intermediaires de quinolones
CA3053869A1 (fr) Protodecarboxylation a catalyse par metal de transition de derives d'acide .alpha.-halo-acrylique
CA3044654A1 (fr) Procede de production d'un compose triazolopyridine
JP5017101B2 (ja) 不斉四置換炭素原子含有化合物の製法
KR20210127961A (ko) 방법 및 화합물
CA2975072A1 (fr) Procede de production d'un compose pyrazine carboxamide, et intermediaire de synthese de ce dernier
AU2005300241A1 (en) Methods for preparing indazole compounds
WO2010098496A1 (fr) Procédé de production d'un dérivé de tétrahydrotriazolopyridine
JP5073497B2 (ja) テトラ置換−５−アザスピロ［２．４］へプタン誘導体の製法およびその光学活性中間体
CZ614690A3 (en) 3-methoxy-4-£1-methyl-5-(2-methyl-4,4,4-trifluorobutylcarbamoyl) indol-3-ylmethyl|-n-(2-methylphenylsulfonyl)benzamide, pharmaceutically acceptable salt thereof, process of their preparation and pharmaceutical compositions containing thereof
WO2009154940A1 (fr) Processus de préparation de composés inhibiteurs de rho-kinase
WO2002070477A1 (fr) Acide 2-methylindole-4-acetique, son procede de production et procede pour produire un produit intermediaire de celui-ci
CA3214107A1 (fr) Nouveau procede de synthese de derives de 5-{5-chloro-2-[(3s)-3-[(morpholin-4-yl)methyl]-3,4-dihydroisoquinoleine-2(1h)-carbonyl]phenyl}-1,2-dimethyl-1h-pyrrole-3-acide carboxylique et son application pour la production de composes pharmaceutiques
JP2022025121A (ja) プロリンアミド化合物の製造方法

Legal Events

Date Code Title Description
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 24 AUG 2007

MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period