TW200630345A - Methods for preparing indazole compounds - Google Patents
Methods for preparing indazole compoundsInfo
- Publication number
- TW200630345A TW200630345A TW094138277A TW94138277A TW200630345A TW 200630345 A TW200630345 A TW 200630345A TW 094138277 A TW094138277 A TW 094138277A TW 94138277 A TW94138277 A TW 94138277A TW 200630345 A TW200630345 A TW 200630345A
- Authority
- TW
- Taiwan
- Prior art keywords
- methods
- indazole compounds
- compounds
- formula
- protein kinases
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
The invention relates to methods for preparing compounds of formula I: or pharmaceutically acceptable salts or solvates thereof. Compounds of the formula I are useful as anti-angiogenesis agents and as agents for modulating and/or inhibiting the activity of protein kinases, thus providing treatments for cancer or other diseases associated with cellular proliferation mediated by protein kinases.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62471904P | 2004-11-02 | 2004-11-02 | |
US62480104P | 2004-12-14 | 2004-12-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200630345A true TW200630345A (en) | 2006-09-01 |
Family
ID=35456957
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW094138277A TW200630345A (en) | 2004-11-02 | 2005-11-01 | Methods for preparing indazole compounds |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1814859A2 (en) |
KR (1) | KR20070085727A (en) |
AU (1) | AU2005300241A1 (en) |
CA (1) | CA2591313A1 (en) |
IL (1) | IL183605A0 (en) |
MX (1) | MX2007006554A (en) |
RU (1) | RU2007120635A (en) |
TW (1) | TW200630345A (en) |
WO (1) | WO2006048761A2 (en) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2136284A1 (en) * | 1971-02-08 | 1972-08-31 | Diamond Shamrock Corp., Cleveland, Ohio (V.StA.) | Herbicidal pyrrolidinyl-carboxanilides - from arylisocyanates and pyrrolidines in organic solvents |
PE20010306A1 (en) * | 1999-07-02 | 2001-03-29 | Agouron Pharma | INDAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM USEFUL FOR THE INHIBITION OF PROTEIN KINASE |
-
2005
- 2005-10-21 AU AU2005300241A patent/AU2005300241A1/en not_active Abandoned
- 2005-10-21 EP EP05797459A patent/EP1814859A2/en not_active Withdrawn
- 2005-10-21 CA CA002591313A patent/CA2591313A1/en not_active Abandoned
- 2005-10-21 MX MX2007006554A patent/MX2007006554A/en unknown
- 2005-10-21 KR KR1020077012588A patent/KR20070085727A/en not_active Application Discontinuation
- 2005-10-21 WO PCT/IB2005/003348 patent/WO2006048761A2/en active Application Filing
- 2005-10-21 RU RU2007120635/04A patent/RU2007120635A/en not_active Application Discontinuation
- 2005-11-01 TW TW094138277A patent/TW200630345A/en unknown
-
2007
- 2007-05-31 IL IL183605A patent/IL183605A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2005300241A2 (en) | 2006-05-11 |
MX2007006554A (en) | 2007-06-19 |
WO2006048761A2 (en) | 2006-05-11 |
EP1814859A2 (en) | 2007-08-08 |
AU2005300241A1 (en) | 2006-05-11 |
KR20070085727A (en) | 2007-08-27 |
CA2591313A1 (en) | 2006-05-11 |
RU2007120635A (en) | 2008-12-10 |
IL183605A0 (en) | 2007-09-20 |
WO2006048761A3 (en) | 2006-06-22 |
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