AU2005278896B2 - Improvements relating to meningococcal outer membrane vesicles - Google Patents

Improvements relating to meningococcal outer membrane vesicles Download PDF

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Publication number
AU2005278896B2
AU2005278896B2 AU2005278896A AU2005278896A AU2005278896B2 AU 2005278896 B2 AU2005278896 B2 AU 2005278896B2 AU 2005278896 A AU2005278896 A AU 2005278896A AU 2005278896 A AU2005278896 A AU 2005278896A AU 2005278896 B2 AU2005278896 B2 AU 2005278896B2
Authority
AU
Australia
Prior art keywords
serosubtype
meningococcus
meningococcal
omvs
outer membrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005278896A
Other languages
English (en)
Other versions
AU2005278896A1 (en
Inventor
Philipp Oster
Mariagrazia Pizza
Rino Rappuoli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GSK Vaccines SRL
Original Assignee
Novartis Vaccines and Diagnostics SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines and Diagnostics SRL filed Critical Novartis Vaccines and Diagnostics SRL
Publication of AU2005278896A1 publication Critical patent/AU2005278896A1/en
Application granted granted Critical
Publication of AU2005278896B2 publication Critical patent/AU2005278896B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
AU2005278896A 2004-09-03 2005-09-05 Improvements relating to meningococcal outer membrane vesicles Ceased AU2005278896B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0419627.5A GB0419627D0 (en) 2004-09-03 2004-09-03 Immunogenic bacterial vesicles with outer membrane proteins
GB0419627.5 2004-09-03
PCT/IB2005/002801 WO2006024946A2 (en) 2004-09-03 2005-09-05 Improvements relating to meningococcal outer membrane vesicles

Publications (2)

Publication Number Publication Date
AU2005278896A1 AU2005278896A1 (en) 2006-03-09
AU2005278896B2 true AU2005278896B2 (en) 2011-12-22

Family

ID=33156002

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005278896A Ceased AU2005278896B2 (en) 2004-09-03 2005-09-05 Improvements relating to meningococcal outer membrane vesicles

Country Status (13)

Country Link
US (1) US8808711B2 (enExample)
EP (1) EP1784213B1 (enExample)
JP (2) JP2008511608A (enExample)
CN (2) CN101115501A (enExample)
AU (1) AU2005278896B2 (enExample)
BR (1) BRPI0514883A (enExample)
CA (1) CA2578588A1 (enExample)
ES (1) ES2527859T3 (enExample)
GB (1) GB0419627D0 (enExample)
MX (1) MX2007002633A (enExample)
NZ (1) NZ553521A (enExample)
RU (1) RU2420312C2 (enExample)
WO (1) WO2006024946A2 (enExample)

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US10828361B2 (en) * 2006-03-22 2020-11-10 Glaxosmithkline Biologicals Sa Regimens for immunisation with meningococcal conjugates
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PL2268618T3 (pl) 2008-03-03 2015-11-30 Novartis Ag Związki i kompozycje jako modulatory aktywności receptorów TLR
US9387239B2 (en) * 2008-05-30 2016-07-12 U.S. Army Medical Research And Materiel Command Meningococcal multivalent native outer membrane vesicle vaccine, methods of making and use thereof
GB0822634D0 (en) * 2008-12-11 2009-01-21 Novartis Ag Meningitis vaccines
BRPI0923006A2 (pt) 2008-12-17 2016-03-08 Novartis Ag vacinas meningococicas incluindo receptor de hemoglobina
CN102762226A (zh) 2009-06-10 2012-10-31 诺华有限公司 含苯并萘啶的疫苗
CN102740882A (zh) 2009-08-27 2012-10-17 诺华有限公司 含有铝、寡核苷酸和聚阳离子的佐剂
JO3257B1 (ar) 2009-09-02 2018-09-16 Novartis Ag مركبات وتركيبات كمعدلات لفاعلية tlr
ES2443952T3 (es) 2009-09-02 2014-02-21 Novartis Ag Composiciones inmunógenas que incluyen moduladores de la actividad de TLR
WO2011057148A1 (en) 2009-11-05 2011-05-12 Irm Llc Compounds and compositions as tlr-7 activity modulators
US9408907B2 (en) 2009-12-15 2016-08-09 Glaxosmithkline Biologicals Sa Homogenous suspension of immunopotentiating compounds and uses thereof
WO2012020326A1 (en) 2010-03-18 2012-02-16 Novartis Ag Adjuvanted vaccines for serogroup b meningococcus
JP5848748B2 (ja) 2010-03-23 2016-01-27 アイアールエム・リミテッド・ライアビリティ・カンパニーＩｒｍ，Ｌｌｃ 感染症、炎症、呼吸器疾患などの処置に使用するｔｌｒ２アゴニストとしての化合物（システインベースのリポペプチド）および組成物
AU2011300418B2 (en) 2010-09-10 2016-05-12 Glaxosmithkline Biologicals Sa Meningococcus overexpressing NadA and/or NHBA and outer membrane vesicles derived therefrom
WO2012153302A1 (en) 2011-05-12 2012-11-15 Novartis Ag Antipyretics to enhance tolerability of vesicle-based vaccines
MX2014008988A (es) 2012-02-02 2014-08-27 Novartis Ag Promotores para aumento de expresion de proteinas en meningococo.
US10598666B2 (en) 2012-03-08 2020-03-24 Glaxosmithkline Biologicals Sa In vitro potency assay for protein-based meningococcal vaccines
EP2833911A4 (en) 2012-04-06 2016-07-13 Univ Cornell SUB-VACCINE VACCINATING PLATFORM FOR ROBUST HUMORAL AND CELLULAR IMMUNE RESPONSES
US10376573B2 (en) 2012-06-14 2019-08-13 Glaxosmithkline Biologicals Sa Vaccines for serogroup X meningococcus
RU2015106930A (ru) 2012-09-06 2016-10-20 Новартис Аг Комбинированные вакцины с менингококком серогруппы в и к/д/с
RU2662970C2 (ru) 2012-09-18 2018-07-31 Новартис Аг Везикулы наружной мембраны
US20160120818A1 (en) 2013-02-07 2016-05-05 Glaxosmithline Biological Sa Pharmaceutical compositions comprising vesicles
CA2940447C (en) 2014-02-28 2023-07-11 Glaxosmithkline Biologicals Sa Modified meningococcal fhbp polypeptides
EA201692552A1 (ru) 2014-07-17 2017-06-30 Глаксосмитклайн Байолоджикалс С.А. МОДИФИЦИРОВАННЫЕ МЕНИНГОКОККОВЫЕ ПОЛИПЕПТИДЫ fHbp
AR101225A1 (es) 2014-07-17 2016-11-30 Glaxosmithkline Biologicals Sa Vacunas de meningococos
KR101742236B1 (ko) * 2014-10-29 2017-05-31 인하대학교 산학협력단 쯔쯔가무시병에 대한 면역 조성물 및 이의 제조방법
CN105669964B (zh) * 2016-03-04 2017-11-21 博瑞生物医药（苏州）股份有限公司 卵巢癌特异靶向的生物可降解双亲性聚合物、由其制备的聚合物囊泡及应用
JP7104027B2 (ja) 2016-09-02 2022-07-20 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 淋菌に対するワクチン
AR113011A1 (es) 2017-09-08 2020-01-15 Evelo Biosciences Inc Vesículas extracelulares bacterianas
GB202115077D0 (en) 2021-10-21 2021-12-08 Glaxosmithkline Biologicals Sa Assay

Citations (4)

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WO2002009643A2 (en) * 2000-07-27 2002-02-07 Children's Hospital & Research Center At Oakland Vaccines for broad spectrum protection against diseases caused by neisseria meningitidis
WO2003105890A2 (en) * 2002-06-13 2003-12-24 Glaxosmithkline Biologicals S.A. Vaccine composition
WO2004019977A2 (en) * 2002-08-30 2004-03-11 Chiron Srl Improved bacterial outer membrane vesicles
WO2004054611A1 (en) * 2002-12-16 2004-07-01 Nasjonalt Folkehelseinstitutt Meningococcal vaccine based on outer membrane proteins porb2 and pora

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WO2003105890A2 (en) * 2002-06-13 2003-12-24 Glaxosmithkline Biologicals S.A. Vaccine composition
WO2004019977A2 (en) * 2002-08-30 2004-03-11 Chiron Srl Improved bacterial outer membrane vesicles
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Also Published As

Publication number Publication date
NZ553521A (en) 2010-01-29
EP1784213A2 (en) 2007-05-16
US8808711B2 (en) 2014-08-19
CN101115501A (zh) 2008-01-30
WO2006024946A3 (en) 2006-11-30
GB0419627D0 (en) 2004-10-06
RU2420312C2 (ru) 2011-06-10
ES2527859T3 (es) 2015-01-30
US20080063665A1 (en) 2008-03-13
CA2578588A1 (en) 2006-03-09
MX2007002633A (es) 2007-05-15
JP2008511608A (ja) 2008-04-17
AU2005278896A1 (en) 2006-03-09
CN101862451A (zh) 2010-10-20
EP1784213B1 (en) 2014-10-29
BRPI0514883A (pt) 2008-06-24
WO2006024946A2 (en) 2006-03-09
RU2007111838A (ru) 2008-10-10
JP2011236254A (ja) 2011-11-24

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired