AU2005262701B2 - Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia - Google Patents

Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia Download PDF

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Publication number
AU2005262701B2
AU2005262701B2 AU2005262701A AU2005262701A AU2005262701B2 AU 2005262701 B2 AU2005262701 B2 AU 2005262701B2 AU 2005262701 A AU2005262701 A AU 2005262701A AU 2005262701 A AU2005262701 A AU 2005262701A AU 2005262701 B2 AU2005262701 B2 AU 2005262701B2
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AU
Australia
Prior art keywords
reaction chamber
gram negative
breath condensate
exhaled breath
lipopolysaccharide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005262701A
Other languages
English (en)
Other versions
AU2005262701A1 (en
Inventor
Jackeline Hernandez
Jeffrey A. Kline
John Albert Watts Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Charlotte Mecklenburg Hospital
Original Assignee
Charlotte Mecklenburg Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Charlotte Mecklenburg Hospital filed Critical Charlotte Mecklenburg Hospital
Publication of AU2005262701A1 publication Critical patent/AU2005262701A1/en
Application granted granted Critical
Publication of AU2005262701B2 publication Critical patent/AU2005262701B2/en
Priority to AU2012201119A priority Critical patent/AU2012201119A1/en
Priority to AU2012201117A priority patent/AU2012201117A1/en
Priority to AU2012201120A priority patent/AU2012201120A1/en
Priority to AU2012201118A priority patent/AU2012201118A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • A61B5/0813Measurement of pulmonary parameters by tracers, e.g. radioactive tracers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • A61B5/083Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • A61B5/097Devices for facilitating collection of breath or for directing breath into or through measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/41Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/412Detecting or monitoring sepsis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/579Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/50Lipopolysaccharides; LPS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Surgery (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Physiology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
AU2005262701A 2004-06-07 2005-05-24 Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia Ceased AU2005262701B2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2012201119A AU2012201119A1 (en) 2004-06-07 2012-02-27 Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia
AU2012201117A AU2012201117A1 (en) 2004-06-07 2012-02-27 Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia
AU2012201120A AU2012201120A1 (en) 2004-06-07 2012-02-27 Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia
AU2012201118A AU2012201118A1 (en) 2004-06-07 2012-02-27 Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57764104P 2004-06-07 2004-06-07
US60/577,641 2004-06-07
PCT/US2005/018232 WO2006007180A2 (en) 2004-06-07 2005-05-24 Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia

Related Child Applications (4)

Application Number Title Priority Date Filing Date
AU2012201119A Division AU2012201119A1 (en) 2004-06-07 2012-02-27 Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia
AU2012201118A Division AU2012201118A1 (en) 2004-06-07 2012-02-27 Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia
AU2012201117A Division AU2012201117A1 (en) 2004-06-07 2012-02-27 Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia
AU2012201120A Division AU2012201120A1 (en) 2004-06-07 2012-02-27 Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia

Publications (2)

Publication Number Publication Date
AU2005262701A1 AU2005262701A1 (en) 2006-01-19
AU2005262701B2 true AU2005262701B2 (en) 2011-12-01

Family

ID=35784291

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005262701A Ceased AU2005262701B2 (en) 2004-06-07 2005-05-24 Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia

Country Status (8)

Country Link
EP (1) EP1761166A4 (enExample)
JP (2) JP4804464B2 (enExample)
AU (1) AU2005262701B2 (enExample)
BR (1) BRPI0511846A (enExample)
CA (1) CA2566804A1 (enExample)
IL (5) IL179137A (enExample)
MX (1) MXPA06014248A (enExample)
WO (1) WO2006007180A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7547285B2 (en) 2003-02-14 2009-06-16 The Charlotte-Mecklenburg Hospital Authority Device and method for collection of exhaled alveolar breath condensate
US7828741B2 (en) 2002-12-20 2010-11-09 The Charlotte-Mecklenburg Hospital Authority Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia
EP1571985B1 (en) 2002-12-20 2009-04-01 The Charlotte-Mecklenburg Hospital Authority Disposable hand-held device for collection of exhaled breath condensate
KR20100084528A (ko) * 2007-10-02 2010-07-26 안나-카린 올린 호기 입자의 수집 및 측정
RU2010146772A (ru) * 2008-06-04 2012-07-20 КейСиАй Лайсензинг, Инк. (US) Обнаружение инфекции при терапии ран пониженным давлением
GB201312635D0 (en) * 2013-07-15 2013-08-28 Univ Plymouth Water testing
US10413216B2 (en) * 2016-02-03 2019-09-17 Quintron Instrument Company, Inc. Breath testing apparatus
CN106018362B (zh) * 2016-05-16 2018-06-08 江苏国恒检测有限公司 一种检测苦味酸的测定器
CN108871908B9 (zh) * 2018-09-06 2024-07-26 杭州优思达生物技术股份有限公司 生物样本处理装置
EP4013302A1 (en) * 2019-08-13 2022-06-22 Respiration Scan Ltd System and method for determining onset and disease progression
CN114449957B (zh) * 2019-08-26 2023-11-24 泽特奥科技公司 利用呼出气诊断结核病和其他疾病
WO2023038582A2 (en) * 2021-09-10 2023-03-16 National University Of Singapore Exhaled breath condensate collection kit
EP4404848A1 (en) * 2021-09-20 2024-07-31 Vosbio, Inc. Devices, methods and kits for biological sample capture and processing
AU2024283662A1 (en) * 2023-06-05 2025-12-04 Charles River Laboratories, Inc. Recombinant amebocyte clotting factors and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4349626A (en) * 1980-10-28 1982-09-14 The Monell Chemical Senses Center Method of detecting Pseudomonas aeruginosa infections utilizing selected ketone and/or sulfur metabolites
US5541057A (en) * 1989-09-18 1996-07-30 Biostar, Inc. Methods for detection of an analyte
US20040234971A1 (en) * 2001-02-01 2004-11-25 Joany Jackman Diagnosis of pathogen infections using mass spectral analysis of immune system modulators in post-exposure biological samples

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59383A (en) * 1980-02-14 1983-03-31 Technion Res & Dev Foundation Micromethod for the determination of endotoxins with limulus amebocyte lysate
SE9704329D0 (sv) * 1997-11-25 1997-11-25 Siemens Elema Ab Gasmätare
EP1139870A4 (en) * 1998-12-18 2004-07-28 Univ Virginia DEVICE AND METHOD FOR MONITORING ASTHMA
EP1169640B1 (en) * 1999-03-09 2005-06-15 Osmetech PLC Method for detecting conditions by analysis of aqueous condensate from respiratory gases
AU2001261091A1 (en) * 2000-05-01 2001-11-12 Respiratory Research, Inc. Method and device for collecting and analyzing exhaled breath

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4349626A (en) * 1980-10-28 1982-09-14 The Monell Chemical Senses Center Method of detecting Pseudomonas aeruginosa infections utilizing selected ketone and/or sulfur metabolites
US5541057A (en) * 1989-09-18 1996-07-30 Biostar, Inc. Methods for detection of an analyte
US20040234971A1 (en) * 2001-02-01 2004-11-25 Joany Jackman Diagnosis of pathogen infections using mass spectral analysis of immune system modulators in post-exposure biological samples

Also Published As

Publication number Publication date
IL179137A (en) 2012-07-31
BRPI0511846A (pt) 2008-01-15
WO2006007180A3 (en) 2006-11-30
IL218188A0 (en) 2012-04-30
MXPA06014248A (es) 2007-06-25
IL218191A0 (en) 2012-04-30
WO2006007180A2 (en) 2006-01-19
EP1761166A2 (en) 2007-03-14
IL179137A0 (en) 2007-03-08
CA2566804A1 (en) 2006-01-19
JP2009186487A (ja) 2009-08-20
AU2005262701A1 (en) 2006-01-19
JP4852121B2 (ja) 2012-01-11
IL218190A0 (en) 2012-04-30
IL218189A0 (en) 2012-04-30
EP1761166A4 (en) 2009-11-11
JP4804464B2 (ja) 2011-11-02
JP2008501976A (ja) 2008-01-24

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired