EP1761166A4 - USE OF LIPOPOLYSACCHARIDE IN EXTRACTED BREATHING CONDENSATE FOR THE DIAGNOSIS OF GRAMNEGATIVE PNEUMONIA - Google Patents

USE OF LIPOPOLYSACCHARIDE IN EXTRACTED BREATHING CONDENSATE FOR THE DIAGNOSIS OF GRAMNEGATIVE PNEUMONIA

Info

Publication number
EP1761166A4
EP1761166A4 EP05753778A EP05753778A EP1761166A4 EP 1761166 A4 EP1761166 A4 EP 1761166A4 EP 05753778 A EP05753778 A EP 05753778A EP 05753778 A EP05753778 A EP 05753778A EP 1761166 A4 EP1761166 A4 EP 1761166A4
Authority
EP
European Patent Office
Prior art keywords
lipopolysaccharide
diagnosis
condensation
gram negative
negative pneumonia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05753778A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1761166A2 (en
Inventor
Jeffrey A Kline
Jackeline Hernandez
John Albert Watts Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Charlotte Mecklenburg Hospital
Original Assignee
Charlotte Mecklenburg Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Charlotte Mecklenburg Hospital filed Critical Charlotte Mecklenburg Hospital
Publication of EP1761166A2 publication Critical patent/EP1761166A2/en
Publication of EP1761166A4 publication Critical patent/EP1761166A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/0813—Measurement of pulmonary parameters by tracers, e.g. radioactive tracers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/412—Detecting or monitoring sepsis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/50—Lipopolysaccharides; LPS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Surgery (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Physiology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
EP05753778A 2004-06-07 2005-05-24 USE OF LIPOPOLYSACCHARIDE IN EXTRACTED BREATHING CONDENSATE FOR THE DIAGNOSIS OF GRAMNEGATIVE PNEUMONIA Withdrawn EP1761166A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57764104P 2004-06-07 2004-06-07
PCT/US2005/018232 WO2006007180A2 (en) 2004-06-07 2005-05-24 Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia

Publications (2)

Publication Number Publication Date
EP1761166A2 EP1761166A2 (en) 2007-03-14
EP1761166A4 true EP1761166A4 (en) 2009-11-11

Family

ID=35784291

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05753778A Withdrawn EP1761166A4 (en) 2004-06-07 2005-05-24 USE OF LIPOPOLYSACCHARIDE IN EXTRACTED BREATHING CONDENSATE FOR THE DIAGNOSIS OF GRAMNEGATIVE PNEUMONIA

Country Status (8)

Country Link
EP (1) EP1761166A4 (enExample)
JP (2) JP4804464B2 (enExample)
AU (1) AU2005262701B2 (enExample)
BR (1) BRPI0511846A (enExample)
CA (1) CA2566804A1 (enExample)
IL (5) IL179137A (enExample)
MX (1) MXPA06014248A (enExample)
WO (1) WO2006007180A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7547285B2 (en) 2003-02-14 2009-06-16 The Charlotte-Mecklenburg Hospital Authority Device and method for collection of exhaled alveolar breath condensate
US7828741B2 (en) 2002-12-20 2010-11-09 The Charlotte-Mecklenburg Hospital Authority Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia
EP1571985B1 (en) 2002-12-20 2009-04-01 The Charlotte-Mecklenburg Hospital Authority Disposable hand-held device for collection of exhaled breath condensate
KR20100084528A (ko) * 2007-10-02 2010-07-26 안나-카린 올린 호기 입자의 수집 및 측정
RU2010146772A (ru) * 2008-06-04 2012-07-20 КейСиАй Лайсензинг, Инк. (US) Обнаружение инфекции при терапии ран пониженным давлением
GB201312635D0 (en) * 2013-07-15 2013-08-28 Univ Plymouth Water testing
US10413216B2 (en) * 2016-02-03 2019-09-17 Quintron Instrument Company, Inc. Breath testing apparatus
CN106018362B (zh) * 2016-05-16 2018-06-08 江苏国恒检测有限公司 一种检测苦味酸的测定器
CN108871908B9 (zh) * 2018-09-06 2024-07-26 杭州优思达生物技术股份有限公司 生物样本处理装置
EP4013302A1 (en) * 2019-08-13 2022-06-22 Respiration Scan Ltd System and method for determining onset and disease progression
CN114449957B (zh) * 2019-08-26 2023-11-24 泽特奥科技公司 利用呼出气诊断结核病和其他疾病
WO2023038582A2 (en) * 2021-09-10 2023-03-16 National University Of Singapore Exhaled breath condensate collection kit
EP4404848A1 (en) * 2021-09-20 2024-07-31 Vosbio, Inc. Devices, methods and kits for biological sample capture and processing
AU2024283662A1 (en) * 2023-06-05 2025-12-04 Charles River Laboratories, Inc. Recombinant amebocyte clotting factors and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001084112A1 (en) * 2000-05-01 2001-11-08 Respiratory Research, Inc. Method and device for collecting and analyzing exhaled breath

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59383A (en) * 1980-02-14 1983-03-31 Technion Res & Dev Foundation Micromethod for the determination of endotoxins with limulus amebocyte lysate
US4349626A (en) * 1980-10-28 1982-09-14 The Monell Chemical Senses Center Method of detecting Pseudomonas aeruginosa infections utilizing selected ketone and/or sulfur metabolites
US5541057A (en) * 1989-09-18 1996-07-30 Biostar, Inc. Methods for detection of an analyte
SE9704329D0 (sv) * 1997-11-25 1997-11-25 Siemens Elema Ab Gasmätare
EP1139870A4 (en) * 1998-12-18 2004-07-28 Univ Virginia DEVICE AND METHOD FOR MONITORING ASTHMA
EP1169640B1 (en) * 1999-03-09 2005-06-15 Osmetech PLC Method for detecting conditions by analysis of aqueous condensate from respiratory gases
US20040234971A1 (en) * 2001-02-01 2004-11-25 Joany Jackman Diagnosis of pathogen infections using mass spectral analysis of immune system modulators in post-exposure biological samples

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001084112A1 (en) * 2000-05-01 2001-11-08 Respiratory Research, Inc. Method and device for collecting and analyzing exhaled breath

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FLANAGAN P G ET AL: "Diagnosis of Gram negative, ventilator associated pneumonia by assaying endotoxin in bronchial lavage fluid", JOURNAL OF CLINICAL PATHOLOGY, BMJ PUBLISHING GROUP, vol. 54, 1 January 2001 (2001-01-01), pages 107 - 110, XP009122143, ISSN: 0021-9746 *
NAYERI F ET AL: "Exhaled breath condensate and serum levels of hepatocyte growth factor in pneumonia", RESPIRATORY MEDICINE, BAILLIERE TINDALL, LONDON, GB, vol. 96, 10 December 2002 (2002-12-10), pages 115 - 119, XP007909654, ISSN: 0954-6111 *

Also Published As

Publication number Publication date
IL179137A (en) 2012-07-31
BRPI0511846A (pt) 2008-01-15
WO2006007180A3 (en) 2006-11-30
IL218188A0 (en) 2012-04-30
MXPA06014248A (es) 2007-06-25
AU2005262701B2 (en) 2011-12-01
IL218191A0 (en) 2012-04-30
WO2006007180A2 (en) 2006-01-19
EP1761166A2 (en) 2007-03-14
IL179137A0 (en) 2007-03-08
CA2566804A1 (en) 2006-01-19
JP2009186487A (ja) 2009-08-20
AU2005262701A1 (en) 2006-01-19
JP4852121B2 (ja) 2012-01-11
IL218190A0 (en) 2012-04-30
IL218189A0 (en) 2012-04-30
JP4804464B2 (ja) 2011-11-02
JP2008501976A (ja) 2008-01-24

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