AU2005254998B2 - Soluble ZcytoR14, anti-ZcytoR14 antibodies and binding partners and methods of using in inflammation - Google Patents
Soluble ZcytoR14, anti-ZcytoR14 antibodies and binding partners and methods of using in inflammation Download PDFInfo
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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| PCT/US2005/020521 WO2005123778A2 (en) | 2004-06-10 | 2005-06-10 | Soluble zcytor14, anti-zcytor14 antibodies and binding partners and methods of using in inflammation |
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| AU2005254998A1 AU2005254998A1 (en) | 2005-12-29 |
| AU2005254998B2 true AU2005254998B2 (en) | 2011-10-27 |
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| US20070160576A1 (en) * | 2001-06-05 | 2007-07-12 | Genentech, Inc. | IL-17A/F heterologous polypeptides and therapeutic uses thereof |
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| BRPI0511952A (pt) * | 2004-06-10 | 2008-01-29 | Zymogenetics Inc | receptor solúvel isolado, anticorpo ou fragmento de anticorpo, e, métodos de reduzir inflamação induzida por il-17a ou induzida por il-17f, de tratar um mamìfero afetado com uma doença inflamatória, e uma condição patológica em um indivìduo associada com atividade de zcytor14 |
| CA2596986A1 (en) * | 2005-02-14 | 2006-08-24 | Wyeth | Use of il-17f in diagnosis and therapy of airway inflammation |
| KR20070107703A (ko) * | 2005-02-14 | 2007-11-07 | 와이어쓰 | 인터루킨-１７ｆ 항체 및 기타 ｉｌ-１７ｆ 신호전달안타고니스트 및 그의 용도 |
| DK1931697T3 (da) | 2005-09-28 | 2010-11-08 | Zymogenetics Inc | IL-17A og IL-17F-antagonister og fremgangsmåder til anvendelse af disse |
| WO2007117762A1 (en) * | 2006-02-10 | 2007-10-18 | Zymogenetics, Inc. | Truncated il-17ra soluble receptor and methods of using in inflammation |
| ATE467640T1 (de) * | 2006-02-10 | 2010-05-15 | Zymogenetics Inc | Lösliches il-17rcx4 und verfahren zu dessen anwendung bei entzündungen |
| US7790163B2 (en) * | 2006-03-10 | 2010-09-07 | Zymogenetics, Inc. | Antibodies that bind both IL-17A and IL-17F and methods of using the same |
| CA2646478A1 (en) | 2006-03-10 | 2007-09-20 | Zymogenetics, Inc. | Antibodies that bind both il-17a and il-17f and methods of using the same |
| WO2007117685A2 (en) | 2006-04-07 | 2007-10-18 | Nektar Therapeutics Al, Corporation | Conjugates of an anti-tnf-alpha antibody |
| GB0620729D0 (en) * | 2006-10-18 | 2006-11-29 | Ucb Sa | Biological products |
| FR2908999B1 (fr) * | 2006-11-29 | 2012-04-27 | Biomerieux Sa | Nouveau medicament destine a l'inhibition, la prevention ou le traitement de la polyarthrite rhumatoide. |
| JP2010522564A (ja) | 2007-03-26 | 2010-07-08 | ザイモジェネティクス， インコーポレイテッド | 可溶性ｉｌ−１７ｒａ／ｒｃ融合タンパク質および関連する方法 |
| TW200902064A (en) * | 2007-03-28 | 2009-01-16 | Wyeth Corp | Methods and compositions for modulating IL-17F/IL-17A biological activity |
| US8460647B2 (en) * | 2007-04-20 | 2013-06-11 | Amgen Inc. | Pre-ligand assembly domain of the IL-17 receptor |
| WO2008133684A1 (en) * | 2007-04-27 | 2008-11-06 | Zymogenetics, Inc. | Antibodies that bind both il-17a and il-17f and methods of using the same |
| AU2008266948B2 (en) * | 2007-06-13 | 2012-08-23 | Kirin-Amgen, Inc. | IL-17 heteromeric receptor complex |
| WO2008156865A2 (en) * | 2007-06-20 | 2008-12-24 | Schering Corporation | Joint destruction biomarkers for anti-il-17a therapy of inflammatory joint disease |
| JP2010534664A (ja) * | 2007-07-23 | 2010-11-11 | セントコア・オーソ・バイオテツク・インコーポレーテツド | Ｉｌ−１７拮抗薬を用いた線維症関連疾患治療の方法及び組成物 |
| US20110300154A1 (en) * | 2007-08-21 | 2011-12-08 | Children's Medical Center Corporation | Treatment of airway hyperreactivity |
| WO2009042162A2 (en) * | 2007-09-25 | 2009-04-02 | Genzyme Corporation | Compositions and methods for inhibiting interleukin pathways |
| JP5886523B2 (ja) * | 2008-01-09 | 2016-03-16 | ザ スキーペンズ アイ リサーチ インスティチュート インコーポレイテッド | 眼の炎症性障害を処置するための治療組成物 |
| NZ588674A (en) | 2008-05-05 | 2013-02-22 | Novimmune Sa | Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof |
| WO2011096438A1 (ja) * | 2010-02-03 | 2011-08-11 | 国立大学法人 東京大学 | 腸疾患の治療方法及び治療用医薬組成物 |
| CN102188707B (zh) * | 2011-02-25 | 2015-08-05 | 中国医学科学院基础医学研究所 | Il-17抑制剂在制备治疗流感的药物中的用途 |
| US9284283B2 (en) | 2012-02-02 | 2016-03-15 | Ensemble Therapeutics Corporation | Macrocyclic compounds for modulating IL-17 |
| EP3456741B1 (en) | 2012-05-22 | 2020-12-16 | Bristol-Myers Squibb Company | Il-17a/f il-23 bispecific antibodies and their uses |
| SG11202111175YA (en) * | 2019-04-26 | 2021-11-29 | Prolynx Llc | Slow-release cytokine conjugates |
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| HUE045709T2 (hu) | 2003-07-08 | 2020-01-28 | Genentech Inc | Antagonista antitestek IL-17A/F heterológ polipeptidekhez |
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| KR20070107703A (ko) | 2005-02-14 | 2007-11-07 | 와이어쓰 | 인터루킨-１７ｆ 항체 및 기타 ｉｌ-１７ｆ 신호전달안타고니스트 및 그의 용도 |
| DK1931697T3 (da) | 2005-09-28 | 2010-11-08 | Zymogenetics Inc | IL-17A og IL-17F-antagonister og fremgangsmåder til anvendelse af disse |
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| JP2010522564A (ja) * | 2007-03-26 | 2010-07-08 | ザイモジェネティクス， インコーポレイテッド | 可溶性ｉｌ−１７ｒａ／ｒｃ融合タンパク質および関連する方法 |
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2005
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2006
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2011
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5684032A (en) * | 1994-12-13 | 1997-11-04 | Smithkline Beecham Corporation | Compounds |
| US20020177188A1 (en) * | 1998-05-15 | 2002-11-28 | Genentech, Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
| WO2001004304A1 (en) * | 1999-07-07 | 2001-01-18 | Zymogenetics, Inc. | Human cytokine receptor |
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| US7910540B2 (en) | 2011-03-22 |
| IL208859A0 (en) | 2011-01-31 |
| CN101001871A (zh) | 2007-07-18 |
| JP4903703B2 (ja) | 2012-03-28 |
| CA2569867A1 (en) | 2005-12-29 |
| IL208859A (en) | 2013-01-31 |
| US20070048826A1 (en) | 2007-03-01 |
| WO2005123778A2 (en) | 2005-12-29 |
| AU2005254998A1 (en) | 2005-12-29 |
| NO20070153L (no) | 2007-03-09 |
| IL179356A (en) | 2011-07-31 |
| BRPI0511952A (pt) | 2008-01-29 |
| IL179356A0 (en) | 2007-03-08 |
| US8268773B2 (en) | 2012-09-18 |
| US20110177083A1 (en) | 2011-07-21 |
| US20070048257A1 (en) | 2007-03-01 |
| EP1765865A2 (en) | 2007-03-28 |
| US20060002925A1 (en) | 2006-01-05 |
| WO2005123778A3 (en) | 2006-02-09 |
| MXPA06014465A (es) | 2007-05-16 |
| JP2008509227A (ja) | 2008-03-27 |
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