NO20070153L - Loselig zcytorl4, anti-zcytorl4-antistoffer og bindingspartnere og fremgangsmater for anvendelse ved inflammasjon - Google Patents
Loselig zcytorl4, anti-zcytorl4-antistoffer og bindingspartnere og fremgangsmater for anvendelse ved inflammasjonInfo
- Publication number
- NO20070153L NO20070153L NO20070153A NO20070153A NO20070153L NO 20070153 L NO20070153 L NO 20070153L NO 20070153 A NO20070153 A NO 20070153A NO 20070153 A NO20070153 A NO 20070153A NO 20070153 L NO20070153 L NO 20070153L
- Authority
- NO
- Norway
- Prior art keywords
- zcytorl4
- binding partners
- soluble
- antibodies
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Neurology (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychiatry (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Foreliggende oppfinnelse vedrører blokkering, inhibering, redusering, antagonisering eller nøytralisering av aktiviteten til IL-17F, IL-17A eller både IL-17A og IL-17F polypeptidmolekyler. IL-17A og IL-17F er cytokiner som er involvert i inflammatoriske prosesser og human sykdom. ZcytoRI4 er en felles reseptor for IL-17A og IL-17F. Foreliggende oppfinnelse inkluderer løselig ZcytoRl4, anti-ZcytoR14-antistoff for bindingspartnere, i tillegg til fremgangsmåter for å antagonisere IL-17F, IL-17A eller både IL-17A og IL- 7F ved å benytte slike løselige reseptorer, antistoffer og bindingspartnere.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57880504P | 2004-06-10 | 2004-06-10 | |
PCT/US2005/020521 WO2005123778A2 (en) | 2004-06-10 | 2005-06-10 | Soluble zcytor14, anti-zcytor14 antibodies and binding partners and methods of using in inflammation |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20070153L true NO20070153L (no) | 2007-03-09 |
Family
ID=35407029
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20070153A NO20070153L (no) | 2004-06-10 | 2007-01-09 | Loselig zcytorl4, anti-zcytorl4-antistoffer og bindingspartnere og fremgangsmater for anvendelse ved inflammasjon |
Country Status (11)
Country | Link |
---|---|
US (4) | US7910540B2 (no) |
EP (1) | EP1765865A2 (no) |
JP (1) | JP4903703B2 (no) |
CN (1) | CN101001871A (no) |
AU (1) | AU2005254998B2 (no) |
BR (1) | BRPI0511952A (no) |
CA (1) | CA2569867A1 (no) |
IL (2) | IL179356A (no) |
MX (1) | MXPA06014465A (no) |
NO (1) | NO20070153L (no) |
WO (1) | WO2005123778A2 (no) |
Families Citing this family (29)
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US20070160576A1 (en) * | 2001-06-05 | 2007-07-12 | Genentech, Inc. | IL-17A/F heterologous polypeptides and therapeutic uses thereof |
US7324615B2 (en) * | 2003-12-15 | 2008-01-29 | Microchip Technology Incorporated | Time signal receiver and decoder |
MXPA06014465A (es) * | 2004-06-10 | 2007-05-16 | Zymogenetics Inc | Zcytor14 soluble, anticuerpos anti-zcytor14 y moleculas de union y metodos de uso en inflamacion. |
PE20061391A1 (es) * | 2005-02-14 | 2007-01-09 | Wyeth Corp | Anticuerpos para interleucina-17f y otros antagonistas de la senalizacion de il-17f |
BRPI0608210A2 (pt) | 2005-02-14 | 2010-11-09 | Wyeth Corp | métodos de diagnóstico de um distúrbio relacionado com il-17f em um indivìduo e de seleção de compostos capazes de inibirem a ligação de il-17f em il-17r, uso de um antagonista de il-17f, composição farmacêutica, e, adjuvante de vacina |
ATE481424T1 (de) | 2005-09-28 | 2010-10-15 | Zymogenetics Inc | Il-17a- und il-17f-antagonisten und verwendungsverfahren |
WO2007117762A1 (en) * | 2006-02-10 | 2007-10-18 | Zymogenetics, Inc. | Truncated il-17ra soluble receptor and methods of using in inflammation |
JP2009526084A (ja) * | 2006-02-10 | 2009-07-16 | ザイモジェネティクス, インコーポレイテッド | 可溶性IL−17RCx4および炎症における使用法 |
EP1996622A2 (en) | 2006-03-10 | 2008-12-03 | Zymogenetics, Inc. | Antibodies that bind both il-17a and il-17f and methods of using the same |
US7790163B2 (en) * | 2006-03-10 | 2010-09-07 | Zymogenetics, Inc. | Antibodies that bind both IL-17A and IL-17F and methods of using the same |
WO2007117685A2 (en) | 2006-04-07 | 2007-10-18 | Nektar Therapeutics Al, Corporation | Conjugates of an anti-tnf-alpha antibody |
GB0620729D0 (en) * | 2006-10-18 | 2006-11-29 | Ucb Sa | Biological products |
FR2908999B1 (fr) * | 2006-11-29 | 2012-04-27 | Biomerieux Sa | Nouveau medicament destine a l'inhibition, la prevention ou le traitement de la polyarthrite rhumatoide. |
MX2009010273A (es) | 2007-03-26 | 2009-10-12 | Zymogenetics Inc | Proteinas de fusion il-17ra/rc solubles y metodos relacionados. |
TW200902064A (en) * | 2007-03-28 | 2009-01-16 | Wyeth Corp | Methods and compositions for modulating IL-17F/IL-17A biological activity |
CA2684329A1 (en) * | 2007-04-20 | 2008-10-30 | Amgen Inc. | Identification and method for using the pre-ligand assembly domain of the il-17 receptor |
WO2008133684A1 (en) * | 2007-04-27 | 2008-11-06 | Zymogenetics, Inc. | Antibodies that bind both il-17a and il-17f and methods of using the same |
CA2687720A1 (en) * | 2007-06-13 | 2008-12-24 | Amgen Inc. | Il-17 heteromeric receptor complex |
EP2171449A2 (en) * | 2007-06-20 | 2010-04-07 | Schering Corporation | Joint destruction biomarkers for anti-il-17a therapy of inflammatory joint disease |
WO2009015063A2 (en) * | 2007-07-23 | 2009-01-29 | Centocor | Methods and compositions for treating fibrosis related disorders using il-17 antagonists |
US20110300154A1 (en) * | 2007-08-21 | 2011-12-08 | Children's Medical Center Corporation | Treatment of airway hyperreactivity |
EP2203476B1 (en) | 2007-09-25 | 2016-10-26 | Genzyme Corporation | Compositions and methods for inhibiting interleukin pathways |
CA2711696C (en) | 2008-01-09 | 2021-10-26 | Reza Dana | Therapeutic compositions for treatment of ocular inflammatory disorders |
CA2721713C (en) | 2008-05-05 | 2019-07-09 | Novimmune Sa | Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof |
JPWO2011096438A1 (ja) * | 2010-02-03 | 2013-06-10 | 国立大学法人 東京大学 | 腸疾患の治療方法及び治療用医薬組成物 |
CN102188707B (zh) * | 2011-02-25 | 2015-08-05 | 中国医学科学院基础医学研究所 | Il-17抑制剂在制备治疗流感的药物中的用途 |
WO2013116682A1 (en) | 2012-02-02 | 2013-08-08 | Ensemble Therapeutics Corporation | Macrocyclic compounds for modulating il-17 |
US8945553B2 (en) | 2012-05-22 | 2015-02-03 | Bristol-Myers Squibb Company | Bispecific antibodies to IL-23 and IL-17A/F |
US20220193253A1 (en) * | 2019-04-26 | 2022-06-23 | Prolynx Llc | Slow-release cytokine conjugates |
Family Cites Families (40)
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US5684032A (en) * | 1994-12-13 | 1997-11-04 | Smithkline Beecham Corporation | Compounds |
EP0817847B2 (en) | 1995-03-23 | 2009-09-09 | Immunex Corporation | Il-17 receptor |
US5945511A (en) | 1997-02-20 | 1999-08-31 | Zymogenetics, Inc. | Class II cytokine receptor |
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US20030100051A1 (en) * | 1998-05-12 | 2003-05-29 | Ruben Steven M. | 97 human secreted proteins |
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US6569645B2 (en) * | 1999-05-14 | 2003-05-27 | Genentech, Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
US6579520B2 (en) * | 1998-05-15 | 2003-06-17 | Genentech, Inc. | IL-17 related mammalian cytokine polypeptides (IL-17E) |
AU7276098A (en) | 1997-05-01 | 1998-11-24 | Zymogenetics Inc. | Mammalian cytokine-like receptor |
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US20020182673A1 (en) * | 1998-05-15 | 2002-12-05 | Genentech, Inc. | IL-17 homologous polypedies and therapeutic uses thereof |
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US7339033B2 (en) * | 1998-06-26 | 2008-03-04 | Genentech, Inc. | Pro1481 |
US7465785B2 (en) * | 1999-03-08 | 2008-12-16 | Genentech, Inc. | Polypeptide encoded by a nucleic acid over-expressed in melanoma |
US7507404B2 (en) * | 1999-03-08 | 2009-03-24 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
WO2001004304A1 (en) * | 1999-07-07 | 2001-01-18 | Zymogenetics, Inc. | Human cytokine receptor |
US20030199041A1 (en) * | 1999-07-07 | 2003-10-23 | Presnell Scott R. | Interleukin-17 receptor homologue |
ES2388748T3 (es) | 1999-12-23 | 2012-10-18 | Genentech, Inc. | Polipéptidos homólogos a IL-17 y usos terapéuticos de los mismos |
US20040048249A1 (en) * | 2000-01-21 | 2004-03-11 | Tang Y. Tom | Novel nucleic acids and secreted polypeptides |
WO2001066722A1 (en) | 2000-03-08 | 2001-09-13 | Human Genome Sciences, Inc. | Immune system-related polynucleotides, polypeptides, and antibodies |
MXPA02011617A (es) | 2000-05-24 | 2003-03-10 | Schering Corp | Proteinas de mamiferos receptoras, reactivosy metodos relacionados. |
US20040197306A1 (en) | 2000-05-24 | 2004-10-07 | Gorman Daniel M. | Mammalian receptor proteins; related reagents and methods |
AU2001260847A1 (en) | 2000-05-24 | 2001-12-03 | Genesis Research And Development Corporation Limited | Compositions isolated from skin cells and methods for their use |
WO2002004519A2 (en) | 2000-07-06 | 2002-01-17 | Zymogenetics, Inc. | Murine cytokine receptor |
AU2002225714A1 (en) | 2000-11-10 | 2002-05-21 | The Regents Of The University Of California | Il-17 receptor-like protein, uses thereof, and modulation of catabolic activity of il-17 cytokines on bone and cartilage |
US6905827B2 (en) * | 2001-06-08 | 2005-06-14 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases |
US20030073623A1 (en) * | 2001-07-30 | 2003-04-17 | Drmanac Radoje T. | Novel nucleic acid sequences obtained from various cDNA libraries |
US6681210B2 (en) * | 2001-09-04 | 2004-01-20 | Andrew Jeffrey Kelly | Modular service payroll system |
US20040097447A1 (en) * | 2002-11-16 | 2004-05-20 | Isis Pharmaceuticals Inc. | Modulation of interleukin 22 receptor expression |
AU2004259638C1 (en) | 2003-07-08 | 2018-12-20 | Novartis Pharma Ag | IL-17 A/F heterologous polypeptides and therapeutic uses thereof |
MXPA06014465A (es) * | 2004-06-10 | 2007-05-16 | Zymogenetics Inc | Zcytor14 soluble, anticuerpos anti-zcytor14 y moleculas de union y metodos de uso en inflamacion. |
PE20061391A1 (es) | 2005-02-14 | 2007-01-09 | Wyeth Corp | Anticuerpos para interleucina-17f y otros antagonistas de la senalizacion de il-17f |
US20070249533A1 (en) * | 2005-09-28 | 2007-10-25 | Levin Steven D | Il-17a and il-17f antagonists and methods of using the same |
ATE481424T1 (de) | 2005-09-28 | 2010-10-15 | Zymogenetics Inc | Il-17a- und il-17f-antagonisten und verwendungsverfahren |
JP2009526084A (ja) * | 2006-02-10 | 2009-07-16 | ザイモジェネティクス, インコーポレイテッド | 可溶性IL−17RCx4および炎症における使用法 |
MX2009010273A (es) * | 2007-03-26 | 2009-10-12 | Zymogenetics Inc | Proteinas de fusion il-17ra/rc solubles y metodos relacionados. |
-
2005
- 2005-06-10 MX MXPA06014465A patent/MXPA06014465A/es active IP Right Grant
- 2005-06-10 EP EP05785507A patent/EP1765865A2/en not_active Withdrawn
- 2005-06-10 US US11/150,533 patent/US7910540B2/en active Active
- 2005-06-10 WO PCT/US2005/020521 patent/WO2005123778A2/en active Application Filing
- 2005-06-10 AU AU2005254998A patent/AU2005254998B2/en not_active Ceased
- 2005-06-10 CN CNA2005800271040A patent/CN101001871A/zh active Pending
- 2005-06-10 BR BRPI0511952-9A patent/BRPI0511952A/pt not_active IP Right Cessation
- 2005-06-10 JP JP2007527770A patent/JP4903703B2/ja not_active Expired - Fee Related
- 2005-06-10 CA CA002569867A patent/CA2569867A1/en not_active Abandoned
-
2006
- 2006-10-04 US US11/538,579 patent/US20070048257A1/en not_active Abandoned
- 2006-10-04 US US11/538,574 patent/US20070048826A1/en not_active Abandoned
- 2006-11-16 IL IL179356A patent/IL179356A/en not_active IP Right Cessation
-
2007
- 2007-01-09 NO NO20070153A patent/NO20070153L/no not_active Application Discontinuation
-
2010
- 2010-10-21 IL IL208859A patent/IL208859A/en not_active IP Right Cessation
-
2011
- 2011-01-27 US US13/015,304 patent/US8268773B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US8268773B2 (en) | 2012-09-18 |
EP1765865A2 (en) | 2007-03-28 |
WO2005123778A3 (en) | 2006-02-09 |
BRPI0511952A (pt) | 2008-01-29 |
CA2569867A1 (en) | 2005-12-29 |
IL179356A0 (en) | 2007-03-08 |
IL179356A (en) | 2011-07-31 |
JP2008509227A (ja) | 2008-03-27 |
MXPA06014465A (es) | 2007-05-16 |
IL208859A (en) | 2013-01-31 |
US20060002925A1 (en) | 2006-01-05 |
US20110177083A1 (en) | 2011-07-21 |
US20070048826A1 (en) | 2007-03-01 |
JP4903703B2 (ja) | 2012-03-28 |
CN101001871A (zh) | 2007-07-18 |
US20070048257A1 (en) | 2007-03-01 |
WO2005123778A2 (en) | 2005-12-29 |
AU2005254998A1 (en) | 2005-12-29 |
AU2005254998B2 (en) | 2011-10-27 |
IL208859A0 (en) | 2011-01-31 |
US7910540B2 (en) | 2011-03-22 |
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Legal Events
Date | Code | Title | Description |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |