AU2005247140A1 - Absorbable biocompatible materials - Google Patents
Absorbable biocompatible materials Download PDFInfo
- Publication number
- AU2005247140A1 AU2005247140A1 AU2005247140A AU2005247140A AU2005247140A1 AU 2005247140 A1 AU2005247140 A1 AU 2005247140A1 AU 2005247140 A AU2005247140 A AU 2005247140A AU 2005247140 A AU2005247140 A AU 2005247140A AU 2005247140 A1 AU2005247140 A1 AU 2005247140A1
- Authority
- AU
- Australia
- Prior art keywords
- group
- copolymer
- coating
- hydrophobic
- monomer unit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000000560 biocompatible material Substances 0.000 title description 2
- 239000003814 drug Substances 0.000 claims abstract description 76
- 150000001413 amino acids Chemical class 0.000 claims abstract description 66
- 229940124597 therapeutic agent Drugs 0.000 claims abstract description 62
- 238000000576 coating method Methods 0.000 claims abstract description 61
- 230000002209 hydrophobic effect Effects 0.000 claims abstract description 60
- 229920001577 copolymer Polymers 0.000 claims abstract description 59
- 238000000034 method Methods 0.000 claims abstract description 59
- 239000011248 coating agent Substances 0.000 claims abstract description 46
- 239000002253 acid Substances 0.000 claims abstract description 29
- 238000002513 implantation Methods 0.000 claims abstract description 8
- 125000001183 hydrocarbyl group Chemical group 0.000 claims abstract 13
- 229920000642 polymer Polymers 0.000 claims description 69
- -1 polyethylene Polymers 0.000 claims description 50
- 239000000178 monomer Substances 0.000 claims description 33
- 125000000524 functional group Chemical group 0.000 claims description 27
- 125000003277 amino group Chemical group 0.000 claims description 24
- 125000000217 alkyl group Chemical group 0.000 claims description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 21
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- 229920001308 poly(aminoacid) Polymers 0.000 claims description 20
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 19
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 18
- 229930195733 hydrocarbon Natural products 0.000 claims description 16
- 125000003342 alkenyl group Chemical group 0.000 claims description 15
- 229910052799 carbon Inorganic materials 0.000 claims description 15
- 125000005647 linker group Chemical group 0.000 claims description 15
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- 229910052757 nitrogen Inorganic materials 0.000 claims description 11
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- 229910052736 halogen Inorganic materials 0.000 claims description 9
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- 150000008064 anhydrides Chemical class 0.000 claims description 7
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims description 7
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- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 5
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- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 claims description 4
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- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 claims description 3
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- 239000000047 product Substances 0.000 description 24
- 229920000729 poly(L-lysine) polymer Polymers 0.000 description 22
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- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 description 17
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 16
- 125000001424 substituent group Chemical group 0.000 description 16
- 238000003786 synthesis reaction Methods 0.000 description 16
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- 229940079593 drug Drugs 0.000 description 14
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 12
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- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 12
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 12
- 238000006243 chemical reaction Methods 0.000 description 12
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- NHJVRSWLHSJWIN-UHFFFAOYSA-N 2,4,6-trinitrobenzenesulfonic acid Chemical compound OS(=O)(=O)C1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O NHJVRSWLHSJWIN-UHFFFAOYSA-N 0.000 description 8
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- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 description 6
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
- A61L2300/604—Biodegradation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Prostheses (AREA)
- Coating Of Shaped Articles Made Of Macromolecular Substances (AREA)
- Paints Or Removers (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57425004P | 2004-05-25 | 2004-05-25 | |
| US60/574,250 | 2004-05-25 | ||
| PCT/GB2005/002081 WO2005115492A1 (en) | 2004-05-25 | 2005-05-25 | Absorbable biocompatible materials |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2005247140A1 true AU2005247140A1 (en) | 2005-12-08 |
Family
ID=35056943
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2005247140A Abandoned AU2005247140A1 (en) | 2004-05-25 | 2005-05-25 | Absorbable biocompatible materials |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20060134166A1 (enExample) |
| EP (1) | EP1748805B1 (enExample) |
| JP (1) | JP2008502376A (enExample) |
| CN (1) | CN1956742A (enExample) |
| AT (1) | ATE437664T1 (enExample) |
| AU (1) | AU2005247140A1 (enExample) |
| CA (1) | CA2567194A1 (enExample) |
| DE (1) | DE602005015696D1 (enExample) |
| WO (1) | WO2005115492A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009520040A (ja) | 2005-12-19 | 2009-05-21 | ファーマイン コーポレーション | 治療薬の送達のための疎水性コアの担体組成物、及び同担体組成物の作製法及び使用法 |
| US7858337B2 (en) * | 2007-03-08 | 2010-12-28 | Novartis Ag | Process for the manufacture of a composite material |
| US20090176892A1 (en) * | 2008-01-09 | 2009-07-09 | Pharmain Corporation | Soluble Hydrophobic Core Carrier Compositions for Delivery of Therapeutic Agents, Methods of Making and Using the Same |
| WO2010143646A1 (ja) * | 2009-06-09 | 2010-12-16 | 味の素株式会社 | 繊維構造体 |
| JP5770727B2 (ja) * | 2010-06-16 | 2015-08-26 | テルモ株式会社 | 医療用具の製造方法 |
| JP5910505B2 (ja) * | 2010-12-06 | 2016-04-27 | 味の素株式会社 | 医療用材料及びその製造方法 |
| JP6042876B2 (ja) * | 2012-03-27 | 2016-12-14 | テルモ株式会社 | コーティング組成物および医療機器 |
| WO2013146376A1 (ja) * | 2012-03-27 | 2013-10-03 | テルモ株式会社 | コーティング組成物および医療機器 |
| USRE49528E1 (en) | 2013-04-26 | 2023-05-16 | Biointeractions Ltd. | Bioactive coatings |
| CN105517585B (zh) | 2013-04-26 | 2019-11-22 | 生物相互作用有限公司 | 生物活性涂层 |
| CN105797220B (zh) * | 2014-12-31 | 2020-07-31 | 先健科技(深圳)有限公司 | 可降解铁基合金支架 |
| US10945997B2 (en) * | 2016-01-08 | 2021-03-16 | Nippon Kayaku Kabushiki Kaisha | Polymer derivative of macrolide immunosuppressant |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0179023B1 (fr) * | 1984-10-19 | 1991-01-23 | Battelle Memorial Institute | Polypeptide biodégradable et son utilisation pour le relargage progressif de médicaments |
| JPH01170464A (ja) * | 1987-12-25 | 1989-07-05 | Lion Corp | 生体材料 |
| DE69841937D1 (de) * | 1997-04-21 | 2010-11-25 | California Inst Of Techn | Multifunctionelle polymer-beschichtung |
| GB9811059D0 (en) * | 1998-05-23 | 1998-07-22 | Univ Strathclyde | Polyamino acid vesicles |
| US20030064965A1 (en) * | 2001-10-02 | 2003-04-03 | Jacob Richter | Method of delivering drugs to a tissue using drug-coated medical devices |
| CN1194704C (zh) * | 2001-11-12 | 2005-03-30 | 华东理工大学 | 含有活性药物、主链中具有氨基酸的聚酯及其制备方法 |
| AU2002233097A1 (en) * | 2002-02-28 | 2003-09-09 | Eidgenossische Technische Hochschule Zurich Oberflachentechnik | Biomedical implant surfaces with osteogenic properties |
| US8309112B2 (en) * | 2003-12-24 | 2012-11-13 | Advanced Cardiovascular Systems, Inc. | Coatings for implantable medical devices comprising hydrophilic substances and methods for fabricating the same |
-
2005
- 2005-05-24 US US11/136,340 patent/US20060134166A1/en not_active Abandoned
- 2005-05-25 EP EP05746512A patent/EP1748805B1/en not_active Expired - Lifetime
- 2005-05-25 WO PCT/GB2005/002081 patent/WO2005115492A1/en not_active Ceased
- 2005-05-25 AT AT05746512T patent/ATE437664T1/de not_active IP Right Cessation
- 2005-05-25 AU AU2005247140A patent/AU2005247140A1/en not_active Abandoned
- 2005-05-25 DE DE602005015696T patent/DE602005015696D1/de not_active Expired - Fee Related
- 2005-05-25 CN CNA2005800168088A patent/CN1956742A/zh active Pending
- 2005-05-25 CA CA002567194A patent/CA2567194A1/en not_active Abandoned
- 2005-05-25 JP JP2007514098A patent/JP2008502376A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1748805A1 (en) | 2007-02-07 |
| JP2008502376A (ja) | 2008-01-31 |
| EP1748805B1 (en) | 2009-07-29 |
| ATE437664T1 (de) | 2009-08-15 |
| CN1956742A (zh) | 2007-05-02 |
| CA2567194A1 (en) | 2005-12-08 |
| WO2005115492A1 (en) | 2005-12-08 |
| DE602005015696D1 (de) | 2009-09-10 |
| US20060134166A1 (en) | 2006-06-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1 | Application lapsed section 142(2)(a) - no request for examination in relevant period |