AU2005216192B2 - Topical delivery of a nitric oxide donor to improve body and skin appearance - Google Patents

Topical delivery of a nitric oxide donor to improve body and skin appearance Download PDF

Info

Publication number
AU2005216192B2
AU2005216192B2 AU2005216192A AU2005216192A AU2005216192B2 AU 2005216192 B2 AU2005216192 B2 AU 2005216192B2 AU 2005216192 A AU2005216192 A AU 2005216192A AU 2005216192 A AU2005216192 A AU 2005216192A AU 2005216192 B2 AU2005216192 B2 AU 2005216192B2
Authority
AU
Australia
Prior art keywords
nitric oxide
delivery vehicle
breast
arginine
oxide donor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005216192A
Other languages
English (en)
Other versions
AU2005216192A1 (en
Inventor
Eric Thor Fossel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Strategic Science and Technologies LLC
Original Assignee
Strategic Science and Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Strategic Science and Technologies LLC filed Critical Strategic Science and Technologies LLC
Publication of AU2005216192A1 publication Critical patent/AU2005216192A1/en
Application granted granted Critical
Publication of AU2005216192B2 publication Critical patent/AU2005216192B2/en
Priority to AU2011200202A priority Critical patent/AU2011200202B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2005216192A 2004-02-23 2005-02-23 Topical delivery of a nitric oxide donor to improve body and skin appearance Ceased AU2005216192B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2011200202A AU2011200202B2 (en) 2004-02-23 2011-01-19 Topical delivery of a nitric oxide donor to improve body and skin appearance

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US54621404P 2004-02-23 2004-02-23
US60/546,214 2004-02-23
US56356604P 2004-04-19 2004-04-19
US60/563,566 2004-04-19
PCT/US2005/005726 WO2005081964A2 (en) 2004-02-23 2005-02-23 Topical delivery of a nitric oxide donor to improve body and skin appearance

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2011200202A Division AU2011200202B2 (en) 2004-02-23 2011-01-19 Topical delivery of a nitric oxide donor to improve body and skin appearance

Publications (2)

Publication Number Publication Date
AU2005216192A1 AU2005216192A1 (en) 2005-09-09
AU2005216192B2 true AU2005216192B2 (en) 2010-11-04

Family

ID=34915567

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2005216192A Ceased AU2005216192B2 (en) 2004-02-23 2005-02-23 Topical delivery of a nitric oxide donor to improve body and skin appearance
AU2011200202A Ceased AU2011200202B2 (en) 2004-02-23 2011-01-19 Topical delivery of a nitric oxide donor to improve body and skin appearance

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2011200202A Ceased AU2011200202B2 (en) 2004-02-23 2011-01-19 Topical delivery of a nitric oxide donor to improve body and skin appearance

Country Status (7)

Country Link
US (2) US20080045909A1 (https=)
EP (1) EP1732577B1 (https=)
JP (3) JP5376761B2 (https=)
AU (2) AU2005216192B2 (https=)
CA (1) CA2556967A1 (https=)
ES (1) ES2421142T3 (https=)
WO (1) WO2005081964A2 (https=)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7914814B2 (en) 1997-09-17 2011-03-29 Strategic Science & Technologies, Llc Topical delivery of arginine of cause beneficial effects
US7629384B2 (en) * 1997-09-17 2009-12-08 Strategic Science & Technologies, Llc Topical delivery of L-arginine to cause beneficial effects
EP1732577B1 (en) * 2004-02-23 2013-04-10 Strategic Science & Technologies, LLC Topical delivery of l-arginine to improve body and skin appearance
US9226909B2 (en) 2004-04-19 2016-01-05 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
US20110028548A1 (en) * 2004-04-19 2011-02-03 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
WO2005102307A2 (en) * 2004-04-19 2005-11-03 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
HUP0401422A2 (en) * 2004-07-15 2006-04-28 G Laszlo Meszaros Use of l-arginine as vasoaktive ingredient absorbing through skin for external application
ES2731298T3 (es) 2005-05-27 2019-11-14 Univ North Carolina Chapel Hill Partículas de liberación de óxido nítrico para agentes terapéuticos de óxido nítrico y aplicaciones biomédicas
US20100178319A1 (en) * 2007-03-27 2010-07-15 Lars Lindgren Topical Dermal Delivery Device For Nitric Oxide Delivery
ITBS20070177A1 (it) * 2007-11-15 2009-05-16 Paoli Ambrosi Gianfranco De Composizione per uso topico per ottenere un rapido ed intenso effetto lifting
EP2334279A4 (en) * 2008-10-16 2013-03-20 Novan Inc STAIN OXIDE RELEASING PARTICLES FOR MOUTH CARE APPLICATIONS
KR101643797B1 (ko) 2009-06-24 2016-07-28 스트러티직 사이언스 앤드 테크놀로지스, 엘엘씨 이부프로펜을 함유하는 국소 조성물
WO2010151241A1 (en) 2009-06-24 2010-12-29 Strategic Science & Technologies, Llc Topical composition containing naproxen
US12138268B2 (en) 2009-06-24 2024-11-12 Strategic Science & Technologies, Llc Treatment of erectile dysfunction and other indications
US11684624B2 (en) 2009-06-24 2023-06-27 Strategic Science & Technologies, Llc Treatment of erectile dysfunction and other indications
WO2011022652A1 (en) 2009-08-21 2011-02-24 Novan, Inc. Topical gels
CA2771389C (en) 2009-08-21 2019-04-09 Novan, Inc. Wound dressings, methods of using the same and methods of forming the same
BR112012008508A2 (pt) * 2009-10-13 2017-06-13 Novan Inc revestimento de sol-gel, substrato, método para produzir um revestimento de sol-gel
EP4056193A1 (en) 2010-06-17 2022-09-14 New York University Therapeutic and cosmetic uses and applications of calreticulin
WO2012027827A1 (en) * 2010-08-30 2012-03-08 Oral Delivery Technology Ltd. Nitric oxide amino acid esters for skin rejuvenation
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
JP2014501283A (ja) 2010-12-29 2014-01-20 ストラテジック サイエンス アンド テクノロジーズ, エルエルシー アレルギーおよび他の適応症の処置のためのシステムおよび方法
EP4491225A3 (en) 2010-12-29 2025-03-26 Strategic Science & Technologies, LLC Treatment of erectile dysfunction and other indications
CN103370048B (zh) * 2011-01-05 2016-06-01 花王株式会社 化妆品
WO2012118829A2 (en) 2011-02-28 2012-09-07 Novan, Inc. Tertiary s-nitrosothiol-modified nitricoxide-releasing xerogels and methods of using the same
US10202338B2 (en) 2011-06-21 2019-02-12 Evologie Llc Topical compositions for the treatment of dermatological disorders
WO2013159140A1 (en) * 2012-04-26 2013-10-31 Edser Brenden Eds005 skin cancer cream
EP2968130A1 (en) 2013-03-15 2016-01-20 Strategic Science & Technologies, LLC Transdermal delivery of sildenafil and other phosphodiesterase type 5 inhibitors
JP2016513686A (ja) 2013-03-15 2016-05-16 ストラテジック サイエンス アンド テクノロジーズ, エルエルシー フルチカゾンの経皮製剤
US10517817B2 (en) 2013-05-09 2019-12-31 Syk Technologies, Llc Deep topical systemic nitric oxide therapy apparatus and method
WO2016112201A1 (en) 2015-01-07 2016-07-14 Strategic Science & Technologies, Llc Techniques and systems for transdermal delivery involving treatment of psoriasis, skin cancer, and other indications
US10688069B2 (en) 2016-03-31 2020-06-23 REV Pharmaceuticals LLC Sports health performance composition
US10953096B2 (en) 2017-04-28 2021-03-23 Nitto Denko Corporation Transdermal absorption preparation precursor
CA3083274A1 (en) * 2017-11-27 2019-05-31 Innovus Pharmaceuticals, Inc. Systems and methods for topical creams for warming
WO2019114705A1 (zh) 2017-12-13 2019-06-20 上海小午医药科技有限公司 一种用于预防或治疗与egfr被抑制相关疾病的方法
US11998513B2 (en) 2018-03-01 2024-06-04 The Regents Of The University Of Michigan Two-part nitric oxide generating topical compositions
CN111989095A (zh) 2018-04-16 2020-11-24 上海岸阔医药科技有限公司 预防或治疗肿瘤疗法副作用的方法
CN108619061A (zh) * 2018-07-11 2018-10-09 广东泓睿科技有限公司 一种丰胸乳液及其制备方法
FR3083981B1 (fr) * 2018-07-20 2021-01-15 Semiocare Sas Compositions a usage cosmetique et dermatologique
US20210000910A1 (en) 2019-07-03 2021-01-07 Jysk Skin Solutions Pte Ltd Topical compositions
CA3184420A1 (en) 2020-06-30 2022-01-06 Mark C. Faulkner Compositions and methods for treatment of vaginal infections
WO2022153309A1 (en) * 2021-01-15 2022-07-21 Rich Psc Ltd. Topical composition
CN116685302A (zh) * 2021-01-15 2023-09-01 利勒格有限公司 局部组合物
US12083204B2 (en) 2022-06-02 2024-09-10 L'oreal Topical composition for homeostatic delivery of nitric oxide and uses thereof
CN116496436B (zh) * 2023-04-28 2024-07-05 西安理工大学 多氢键网络基自修复高透明导电弹性体的制备方法及应用
MX2024012712A (es) * 2023-10-24 2025-05-02 Albert Einstein College Medicine Formulaciones de administracion transdermica.

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1553063A (https=) * 1967-11-28 1969-01-10
WO1988006034A1 (en) * 1987-02-13 1988-08-25 Mary Gemma Fiaschetti Dermal cosmetic composition and applications therefor
US5254331A (en) * 1991-09-12 1993-10-19 Chanel, Inc. Skin cream composition
US5538740A (en) * 1991-03-01 1996-07-23 Atherton Investments, Ltd. Therapeutic and cosmetic compositions for treatment of skin
WO1999013717A1 (en) * 1997-09-17 1999-03-25 Strategic Science & Technologies, Inc. A delivery of arginine to cause beneficial effects
WO2000003689A2 (de) * 1998-07-15 2000-01-27 Mandorlo Investment Gmbh Mittel zur pflege und/oder behandlung von haut und gewebe
WO2000040215A1 (fr) * 1998-12-30 2000-07-13 Parfums Christian Dior Composition cosmetique ou dermatologique contenant un actif stimulant la synthese de la proteine hsp 32 dans la peau et methode de traitement cosmetique
FR2810540A1 (fr) * 2000-06-21 2001-12-28 C3D Nouvelles preparations cosmetiques ou hygieniques sous forme de dispersion
EP1210933A1 (en) * 1999-09-07 2002-06-05 Kabushiki Kaisha Soken Skin normalizing agents
DE10128910A1 (de) * 2001-06-15 2002-12-19 Beiersdorf Ag Verwendung von Wirkstoffkombinationen aus Arginin und Ascorbinsäure zur Hautstraffung

Family Cites Families (117)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3960782A (en) * 1974-09-27 1976-06-01 The Procter & Gamble Company Shampoo compositions which impart high luster and manageability to hair
US4185100A (en) * 1976-05-13 1980-01-22 Johnson & Johnson Topical anti-inflammatory drug therapy
FR2557452B1 (fr) * 1983-12-28 1986-08-14 Roussel Uclaf Nouvelles compositions pour les soins de la peau renfermant de l'huile d'onagre et des traits tissulaires de rate
US4681897A (en) * 1984-01-16 1987-07-21 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
US4722837A (en) * 1984-05-29 1988-02-02 Derma-Cure, Inc. Medicated shampoo composition
US4732892A (en) * 1985-07-12 1988-03-22 American Home Products Corporation L-α-amino acids as transdermal penetration enhancers
DE3684564D1 (de) * 1985-11-18 1992-04-30 Beecham Group Plc Veterinaere zusammensetzungen.
GB8606368D0 (en) * 1986-03-14 1986-04-23 Unilever Plc Skin treatment composition
US5925372A (en) * 1987-12-16 1999-07-20 Novartis Corporation Mixed solvent mutually enhanced transdermal therapeutic system
US4871718A (en) * 1987-12-29 1989-10-03 Raymond A. Roncari Composition of matter for increasing intracellular ATP levels and physical performance levels and for increasing the rate of wound repair
DE3827362A1 (de) * 1988-08-12 1990-02-15 Basf Ag Pulvrige, hydrophile theophyllinformulierung und verfahren zur ihrer herstellung
AU4345489A (en) * 1988-09-30 1990-04-18 Duane R. Schultz Anti-inflammatory and analgesic compounds, related compositions and methods for preparation and use thereof
US4945901A (en) * 1989-03-22 1990-08-07 Burcke Jr Harry J Hand therapy apparatus and method therefor
US5158761A (en) * 1989-04-05 1992-10-27 Toko Yakuhin Kogyo Kabushiki Kaisha Spray gel base and spray gel preparation using thereof
US5476852A (en) * 1989-05-03 1995-12-19 Janssen Pharmaceutica N.V. Method of topically treating acne vulgaris, hyperkeratotic dermatoses, and photo-aging of the skin
US5028435A (en) * 1989-05-22 1991-07-02 Advanced Polymer Systems, Inc. System and method for transdermal drug delivery
JP2761939B2 (ja) * 1989-09-04 1998-06-04 株式会社コーセー 水中油型乳化化粧料
US5576351A (en) * 1989-12-29 1996-11-19 Mcgaw, Inc. Use of arginine as an immunostimulator
EP0441119A3 (en) * 1990-01-09 1992-10-14 Richard D. Levere The use of l-arginine in the treatment of hypertension and other vascular disorders
US5332758A (en) * 1990-07-13 1994-07-26 Kanebo, Ltd. Collagen metabolism ameliorant and its use
US5824658A (en) * 1990-09-18 1998-10-20 Hyal Pharmaceutical Corporation Topical composition containing hyaluronic acid and NSAIDS
DE4100975A1 (de) * 1991-01-15 1992-07-16 Weuffen Wolfgang Kosmetische oder pharmazeutische zubereitungen zur verbesserung der haarqualitaet und foerderung des haarwachstums
US5210099A (en) * 1991-02-11 1993-05-11 American Home Products Corporation Analgesic compositions
JPH06509060A (ja) * 1991-03-01 1994-10-13 アーサートン・インベストメンツ・リミテッド 皮膚を処置するための治療用および化粧用組成物
US5498420A (en) * 1991-04-12 1996-03-12 Merz & Co. Gmbh & Co. Stable small particle liposome preparations, their production and use in topical cosmetic, and pharmaceutical compositions
JP2636118B2 (ja) * 1991-09-10 1997-07-30 三省製薬株式会社 育毛剤
US5215759A (en) * 1991-10-01 1993-06-01 Chanel, Inc. Cosmetic composition
US5217652A (en) * 1991-10-04 1993-06-08 The Gillette Company Conditioning shampoo
EP0552879B1 (en) * 1992-01-21 1998-08-19 Macrochem Corporation Improved iontophoretic administration of drugs
US5632981A (en) * 1992-08-24 1997-05-27 The United States Of America As Represented By The Department Of Health And Human Services Biopolymer-bound nitric oxide-releasing compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
US5405919A (en) * 1992-08-24 1995-04-11 The United States Of America As Represented By The Secretary Of Health And Human Services Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions and methods of treating biological disorders
US5691423A (en) * 1992-08-24 1997-11-25 The United States Of America As Represented By The Department Of Health And Human Services Polysaccharide-bound nitric oxide-nucleophile adducts
US5464954A (en) * 1992-08-31 1995-11-07 Idec Izumi Corporation Safety switch assembly
US5439938A (en) * 1993-04-07 1995-08-08 The Johns Hopkins University Treatments for male sexual dysfunction
US5891459A (en) * 1993-06-11 1999-04-06 The Board Of Trustees Of The Leland Stanford Junior University Enhancement of vascular function by modulation of endogenous nitric oxide production or activity
US5428070A (en) * 1993-06-11 1995-06-27 The Board Of Trustees Of The Leland Stanford Junior University Treatment of vascular degenerative diseases by modulation of endogenous nitric oxide production of activity
US5714472A (en) * 1993-12-23 1998-02-03 Nestec Ltd. Enternal formulation designed for optimized nutrient absorption and wound healing
GB9409281D0 (en) * 1994-05-10 1994-06-29 Svedman Paul Transdermal device
US5543430A (en) * 1994-10-05 1996-08-06 Kaesemeyer; W. H. Method and formulation of stimulating nitric oxide synthesis
US5505958A (en) * 1994-10-31 1996-04-09 Algos Pharmaceutical Corporation Transdermal drug delivery device and method for its manufacture
BR9509590A (pt) * 1994-11-04 1997-12-23 Polymun Scient Immunbio Forsch Aplicação de sod em liposomas
US5648101A (en) * 1994-11-14 1997-07-15 Tawashi; Rashad Drug delivery of nitric oxide
US5562917A (en) * 1994-12-23 1996-10-08 Pentech Pharmaceuticals, Inc. Transdermal administration of apomorphine
US5595753A (en) * 1995-04-14 1997-01-21 President And Fellows Of Harvard College Topical formulations and methods for treating hemorrhoidal pain and sphincter and smooth muscle spasm in the gastrointestinal tract
US5643586A (en) * 1995-04-27 1997-07-01 Perricone; Nicholas V. Topical compositions and methods for treatment of skin damage and aging using catecholamines and related compounds
US5762963A (en) * 1995-06-07 1998-06-09 Emory University Method and compositions for controlling oral and pharyngeal pain using capsaicinoids
US5645859A (en) * 1995-10-02 1997-07-08 Isp Investments Inc. Process for producing an alpha or beta-hydroxy acid-vinylpyrrolidone polymer, copolymer or graft polymer complex in the form of free-flowing powders having a high acid loading
US5605685A (en) * 1995-09-13 1997-02-25 Isp Investments Inc. Non-irritating skin and hair rejuvenating compostion having a pH between 1 and 6.5
US6036977A (en) * 1995-09-29 2000-03-14 L.A.M. Pharmaceutical Corp. Drug preparations for treating sexual dysfunction
FR2740339B1 (fr) * 1995-10-26 1997-12-05 Oreal Utilisation d'au moins un inhibiteur de no-synthase dans le traitement des peaux sensibles
US5716436B1 (en) * 1995-11-30 1999-08-24 Eastman Kodak Co Ink jet containing polyester ionomers
US5789442A (en) * 1996-01-18 1998-08-04 Schering Aktiengesellschaft Treatment of urinary incontinence with nitric oxide synthase substrates and/or nitric oxide donors alone or in combination with estrogen or progesterone and/or other agents
GB9608408D0 (en) * 1996-04-23 1996-06-26 Adams Michael A Treatment of erectile dysfunction
US5911980A (en) * 1996-06-27 1999-06-15 Macrochem Corporation Lipophilic and amphiphilic or hydrophilic film-forming polymer compositions, and use thereof in topical agent delivery system and method of delivering agents to the skin
US20020015713A1 (en) * 1996-10-24 2002-02-07 Murdock Robert W. Methods and transdermal compositions for pain relief
US5891472A (en) * 1996-11-19 1999-04-06 Meri Charmyne Russell Treatment of equine laminitis
JPH10167953A (ja) * 1996-12-06 1998-06-23 Daicel Chem Ind Ltd 化粧品組成物
US5807957A (en) * 1996-12-23 1998-09-15 Macrochem Corporation Cationic film-forming polymer compositions, and use thereof in topical agents delivery system and method of delivering agents to the skin
IL120531A (en) * 1997-03-26 2006-12-31 Yissum Res Dev Co Nitric oxide donors and pharmaceutical compositions containing them
FR2762782B1 (fr) * 1997-05-05 1999-06-11 Oreal Composition comprenant un milieu de culture de micro-organisme et utilisation
JP4856295B2 (ja) * 1997-07-03 2012-01-18 アメリカ合衆国政府 新規な一酸化窒素放出アミジン誘導ジアゼニウムジオレート及びその組成物
US5976566A (en) * 1997-08-29 1999-11-02 Macrochem Corporation Non-steroidal antiinflammtory drug formulations for topical application to the skin
US7629384B2 (en) * 1997-09-17 2009-12-08 Strategic Science & Technologies, Llc Topical delivery of L-arginine to cause beneficial effects
US7914814B2 (en) * 1997-09-17 2011-03-29 Strategic Science & Technologies, Llc Topical delivery of arginine of cause beneficial effects
US5895658A (en) * 1997-09-17 1999-04-20 Fossel; Eric T. Topical delivery of L-arginine to cause tissue warming
US6207713B1 (en) * 1997-09-17 2001-03-27 Eric T. Fossel Topical and oral delivery of arginine to cause beneficial effects
US5922332A (en) * 1997-09-17 1999-07-13 Fossel; Eric T. Topical delivery of arginine to overcome pain
US6096759A (en) * 1997-09-19 2000-08-01 Georgetown University Method for treating essential hypertension
US5906822A (en) * 1997-09-25 1999-05-25 Macrochem Corporation Cationic film-forming polymer compositions, and use thereof in topical agents delivery system and method of delivering agents to the skin
EP1021191B1 (de) * 1997-10-08 2002-06-05 Genesiscosmetics Rights & Licenses Company Limited Straffung und/oder verkleinerung von fettzellen-haltigen körperpartien
US6031888A (en) * 1997-11-26 2000-02-29 Picker International, Inc. Fluoro-assist feature for a diagnostic imaging device
GB9801398D0 (en) * 1998-01-22 1998-03-18 Anggard Erik E Chemical compounds
BR9910857A (pt) * 1998-06-01 2001-03-20 Anthony J Verbiscar Tratamentos transdérmicos tópicos.
US6103275A (en) * 1998-06-10 2000-08-15 Nitric Oxide Solutions Systems and methods for topical treatment with nitric oxide
US6117872A (en) * 1998-06-23 2000-09-12 The Board Of Trustees Of The Leland Stanford Junior University Enhancement of exercise performance by augmenting endogenous nitric oxide production or activity
ATE399565T1 (de) * 1998-07-07 2008-07-15 Transdermal Technologies Inc Zusammensetzungen für die schnelle und nicht- irritierende transdermale verabreichung von pharmazeutika and verfahren zur formuliering davon und ihren verabreichung
DE19830649C2 (de) * 1998-07-09 2003-04-10 Lohmann Therapie Syst Lts Topisches Pflaster mit nichtsteroidalen Antirheumatika mit Säuregruppe
AU1231000A (en) * 1998-10-26 2000-05-15 University Of Massachusetts Treatment of skin with adenosine or adenosine analog
US6261594B1 (en) * 1998-11-25 2001-07-17 The University Of Akron Chitosan-based nitric oxide donor compositions
JP2000186028A (ja) * 1998-12-21 2000-07-04 Nobuko Koga 化粧品
AU777395B2 (en) * 1999-03-12 2004-10-14 Mt Industries, Inc. Misting apparatus for application of coating materials to skin surface
US6375672B1 (en) * 1999-03-22 2002-04-23 Board Of Trustees Of Michigan State University Method for controlling the chemical and heat induced responses of collagenous materials
FR2794974B1 (fr) * 1999-06-16 2001-08-17 Exsymol Sa Composition cosmetique pour l'amincissement a base de l-arginine, d'un analogue de l-arginine ou d'un de leurs derives, applicable par voie topique
US6586000B2 (en) * 1999-12-16 2003-07-01 Dermatrends, Inc. Hydroxide-releasing agents as skin permeation enhancers
US6558695B2 (en) * 1999-12-16 2003-05-06 Dermatrends, Inc. Topical and transdermal administration of peptidyl drugs using hydroxide releasing agents as permeation enhancers
US6719997B2 (en) * 2000-06-30 2004-04-13 Dermatrends, Inc. Transdermal administration of pharmacologically active amines using hydroxide-releasing agents as permeation enhancers
US6602912B2 (en) * 2000-06-30 2003-08-05 Dermatrends, Inc. Transdermal administration of phenylpropanolamine
US6582724B2 (en) * 1999-12-16 2003-06-24 Dermatrends, Inc. Dual enhancer composition for topical and transdermal drug delivery
US6565879B1 (en) * 1999-12-16 2003-05-20 Dermatrends, Inc. Topical and transdermal administration of peptidyl drugs with hydroxide-releasing agents as skin permeation enhancers
US6562370B2 (en) * 1999-12-16 2003-05-13 Dermatrends, Inc. Transdermal administration of steroid drugs using hydroxide-releasing agents as permeation enhancers
FR2802414B1 (fr) * 1999-12-20 2003-06-27 G Pharm Lab Composition, notamment cosmetique ou dermatologique, contenant des oligosaccharides, son procede de preparation et un procede de traitement cosmetique
JP2001288068A (ja) * 2000-04-06 2001-10-16 Nof Corp 皮膚化粧料
JP2002003373A (ja) * 2000-06-27 2002-01-09 Shiseido Co Ltd 皮膚外用剤
US6538033B2 (en) * 2000-08-29 2003-03-25 Huntington Medical Research Institutes Nitric oxide donor compounds
US20020168325A1 (en) * 2001-01-25 2002-11-14 Ethan Lerner NOS inhibitors for treatment of wrinkles
WO2002087700A1 (en) * 2001-04-26 2002-11-07 The Procter & Gamble Company Method, kit and device for the treatment of cosmetic skin conditions
US20030157185A1 (en) * 2002-02-08 2003-08-21 Lou Paradise Topical treatment of neuropathy
US20050226821A1 (en) * 2002-02-22 2005-10-13 Jacob Waugh Cosmetic formulations containing l-arginine oligomers
JP2003286129A (ja) * 2002-03-27 2003-10-07 Hakugen:Kk 痩身シート材
US20020168424A1 (en) * 2002-07-31 2002-11-14 Dr. Mohsen Shahinpoor Nitric oxide (NO) donor+cGMP-PDE5 inhibitor as a topical drug for glaucoma
US7241456B2 (en) * 2002-10-25 2007-07-10 Australian Importers Ltd. Formulations for topical delivery of bioactive substances and methods for their use
AU2003903037A0 (en) * 2003-06-17 2003-07-03 Institute Of Nutraceutical Research Connective tissue derived polypeptides
US20070065463A1 (en) * 2003-06-20 2007-03-22 Ronald Aung-Din Topical therapy for the treatment of migranes, muscle sprains, muscle spasms, spasticity and related conditions
US20050069590A1 (en) * 2003-09-30 2005-03-31 Buehler Gail K. Stable suspensions for medicinal dosages
JP2005200370A (ja) * 2004-01-16 2005-07-28 Nikko Chemical Co Ltd 一酸化窒素産生促進剤およびその利用
EP1732577B1 (en) * 2004-02-23 2013-04-10 Strategic Science & Technologies, LLC Topical delivery of l-arginine to improve body and skin appearance
US20110028548A1 (en) * 2004-04-19 2011-02-03 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
US20090105336A1 (en) * 2004-04-19 2009-04-23 Strategic Science & Technologies, Llc Beneficial Effects of Increasing Local Blood Flow
WO2005102307A2 (en) * 2004-04-19 2005-11-03 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
US20070087977A1 (en) * 2004-11-16 2007-04-19 Wendye Robbins Methods and compositions for treating pain
US7442690B2 (en) * 2005-03-14 2008-10-28 P & L Enterprise Llc Topical treatment for psoriasis
EP1770086A1 (de) * 2005-09-29 2007-04-04 Boehringer Ingelheim Pharma GmbH & Co. KG Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
CA2680825C (en) * 2007-03-22 2013-10-29 Cytotech Labs, Llc Topical formulations having enhanced bioavailability
US8686040B2 (en) * 2008-03-31 2014-04-01 Rdd Pharma Ltd. Method for treating anal pruritis and other perianal disorders
US8969081B2 (en) * 2008-12-10 2015-03-03 The Trustees Of Columbia University In The City Of New York Caudal motor neuron derived from embryonic stem cells under conditions essentially free of any retinoid
WO2010151241A1 (en) * 2009-06-24 2010-12-29 Strategic Science & Technologies, Llc Topical composition containing naproxen
KR101643797B1 (ko) * 2009-06-24 2016-07-28 스트러티직 사이언스 앤드 테크놀로지스, 엘엘씨 이부프로펜을 함유하는 국소 조성물

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1553063A (https=) * 1967-11-28 1969-01-10
WO1988006034A1 (en) * 1987-02-13 1988-08-25 Mary Gemma Fiaschetti Dermal cosmetic composition and applications therefor
US5538740A (en) * 1991-03-01 1996-07-23 Atherton Investments, Ltd. Therapeutic and cosmetic compositions for treatment of skin
US5254331A (en) * 1991-09-12 1993-10-19 Chanel, Inc. Skin cream composition
WO1999013717A1 (en) * 1997-09-17 1999-03-25 Strategic Science & Technologies, Inc. A delivery of arginine to cause beneficial effects
WO2000003689A2 (de) * 1998-07-15 2000-01-27 Mandorlo Investment Gmbh Mittel zur pflege und/oder behandlung von haut und gewebe
WO2000040215A1 (fr) * 1998-12-30 2000-07-13 Parfums Christian Dior Composition cosmetique ou dermatologique contenant un actif stimulant la synthese de la proteine hsp 32 dans la peau et methode de traitement cosmetique
EP1210933A1 (en) * 1999-09-07 2002-06-05 Kabushiki Kaisha Soken Skin normalizing agents
FR2810540A1 (fr) * 2000-06-21 2001-12-28 C3D Nouvelles preparations cosmetiques ou hygieniques sous forme de dispersion
DE10128910A1 (de) * 2001-06-15 2002-12-19 Beiersdorf Ag Verwendung von Wirkstoffkombinationen aus Arginin und Ascorbinsäure zur Hautstraffung

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Scholermann A et al. Journal of the European Academy of Dermatology and Venereology, Vol. 11, 1 September 1998, page S270 *

Also Published As

Publication number Publication date
US20080045909A1 (en) 2008-02-21
JP2007523195A (ja) 2007-08-16
AU2011200202A1 (en) 2011-02-10
ES2421142T3 (es) 2013-08-29
WO2005081964A2 (en) 2005-09-09
WO2005081964A3 (en) 2005-12-08
CA2556967A1 (en) 2005-09-09
JP2011116787A (ja) 2011-06-16
JP5376761B2 (ja) 2013-12-25
EP1732577A4 (en) 2009-03-18
EP1732577B1 (en) 2013-04-10
JP2012107071A (ja) 2012-06-07
US20100196517A1 (en) 2010-08-05
EP1732577A2 (en) 2006-12-20
AU2011200202B2 (en) 2013-03-21
AU2005216192A1 (en) 2005-09-09

Similar Documents

Publication Publication Date Title
AU2005216192B2 (en) Topical delivery of a nitric oxide donor to improve body and skin appearance
JP6533840B2 (ja) 勃起不全および他の適応症の処置
EP1737429B1 (en) Transdermal delivery of beneficial substances effected by a high ionic strength environment
US20110028548A1 (en) Beneficial effects of increasing local blood flow
WO2012092525A1 (en) Cox-2 inhibitors and related compounds, and systems and methods for delivery thereof
AU2013203814B2 (en) Transdermal delivery of beneficial substances effected by a hostile biophysical environment transdermal delivery of beneficial substances effected by a hostile biophysical environment
CA2835840C (en) Beneficial effects of increasing local blood flow
CN110302083A (zh) 一种化妆品用防腐剂及其制备方法和应用
AU2015202451A1 (en) Transdermal delivery of beneficial substances effected by a hostile biophysical environment
HK1188943A (en) Transdermal delivery of beneficial substances effected by a hostile biophysical environment

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired